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检索条件:"关键词=apoptosis-related "
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T-2 toxin-induced apoptosis involving Fas,p53,Bcl-xL,Bcl-2,Bax and caspase-3 signaling pathways in human chondrocytes被引量:19
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2008年第6期455-463,共9页Jing-hong CHEN Jun-ling CAO Yong-lie CHU Zhi-lun WANG Zhan-tian YANG Hong-lin WANG 
Project(Nos.3063058 and 30471499)supported by the National Natural Science Foundation of China
Objective:To investigate the effects of T-2 toxin on expressions of Fas,p53,Bcl-xL,Bcl-2,Bax and caspase-3 on human chondrocytes.Methods:Human chondrocytes were treated with T-2 toxin(1~20 ng/ml)for 5 d.Fas,p53 and o...
关键词:APOPTOSIS Apoptosis-related proteins CHONDROCYTE T-2 toxin 
Inhibitory effect of norcantharidin on the growth of human gallbladder carcinoma GBC-SD cells in vitro被引量:25
《Hepatobiliary & Pancreatic Diseases International》2007年第1期72-80,共9页Fan, Yue-Zu Fu, Jin-Ye Zhao, Ze-Ming Chen, Chun-Qiu 
BACKGROUND: Gallbladder carcinoma is a lethal malignant neoplasm with dismal surgical results. Unfortunately, the adjuvant therapies for gallbladder carcinoma such as chemotherapy and radiotherapy are also disappointi...
关键词:NORCANTHARIDIN GALLBLADDER neoplasm GROWTH PROLIFERATION cell cycle APOPTOSIS proliferation- and apoptosis-related genes 
增生性瘢痕成纤维细胞中分泌型凋亡相关蛋白1相互作用蛋白的研究被引量:2
《中华医学美学美容杂志》2014年第5期381-384,共4页王儆 王雪梅 王珍祥 陈亮 李世荣 
国家自然科学基金面上资助项目(81071563,81272102)
目的 寻找与分泌型凋亡相关蛋白1 (secreted apoptosis-related protein1,SARP1)存在相互作用的蛋白质分子,分析其分子机制.方法 成功构建的重组SARP1腺病毒载体Ad-SARP1,转染进入原代培养的增生性瘢痕成纤维细胞(HSFb).免疫共沉淀...
关键词:分泌型凋亡相关蛋白1 增生性瘢痕 成纤维细胞 免疫共沉淀 相互作用蛋白 SECRETED apoptosis-related protein 1 (SARP1) 
Low dose radiation induced adaptive response of apoptosis in mouse spleen cells被引量:1
《The Chinese-German Journal of Clinical Oncology》2010年第4期235-238,共4页Hongsheng Yu Ning Liu Bo Ju 
Objective:The aim of the study was to investigate the adaptive response of low-dose radiation-induced apoptosis in mouse spleen cells and its related proteins control mechanism. Methods: Kunming male mice were randoml...
关键词:low-dose radiation SPLEEN APOPTOSIS apoptosis-related proteins 
Infant guinea pig retina model of glutamate toxicity and intervention of basic fibroblast growth factor
《Neural Regeneration Research》2011年第7期534-541,共8页Yunzhi Shi Lihua Wei Mingshan Song Min Chen Changqing Du Baoliang Sun 
the National Natural Science Foundation of China, No. 81070947;the Scientific Research Funds of Taishan Medical College, No. 200ZR027
Impaired vision with oligemic ophthalmopathy is a result of excitotoxicity caused by excitatory amino acids, resulting in pathological changes, such as loss of retinal neurons and in particular retinal ganglionic cell...
关键词:SYNAPTOPHYSIN SOMATOSTATIN apoptosis-related genes basic fibroblast growth factor GLUTAMATE RETINA 
Size-dependent toxicity of microplastics induced gut cell apoptosis in brine shrimp Artemia parthenogenetica through p53 signaling pathway
《Journal of Oceanology and Limnology》2025年第2期614-623,共10页Junfang WANG Zhichao YAN Yulong LU Wei XIE Liying SUI 
Supported by the Program of Sustainable Development and Protection of Artemia Resources in Yuncheng Salt Lake of China(No.YHYJ-2023005)。
Microplastics(MPs)are one of the most concerning pollutants that affects the health and growth of aquatic organisms.We characterized the MPs dispersion in the milli-Q water and seawater,and evaluated the effects of MP...
关键词:polystyrene microplastic brine shrimp GUT oxidative stress apoptosis-related gene mitochondrial membrane potential 
Research Progress on Anti-tumor Mechanism of Clearing Heat-Toxin Intervention of Apoptosis-related Proteins
《World Journal of Integrated Traditional and Western Medicine》2023年第3期23-33,共11页楚小鸽 魏嘉茵 周晟宇 罗斌 田建辉 
Research Project of Jing'an District,Shanghai,No.2019QN09;Shanghai Youth Science and Technology Talents Sailing Program,No.20YF1449900;The Third Jing'an District Modern Chinese Medicine Teacher Training Project(ZYSC-2022-8)。
Apoptosis is a spontaneous programmed cell death process,which is closely related to the occurrence and development of tumors.Inducing apoptosis of tumor cells has become an important way of anti-tumor therapy.Studies...
关键词:APOPTOSIS Apoptosis-related proteins Clearing heat-toxin ANTI-TUMOR 
c-Jun N-terminal kinase is required for thermotherapyinduced apoptosis in human gastric cancer cells被引量:1
《World Journal of Gastroenterology》2012年第48期7348-7356,共9页Feng Xiao Bin Liu Qing-Xian Zhu 
Supported by A grant from the National Eleventh Five-Year Technology Support Project of China,No. 2008 BAI68B01
AIM:To investigate the role of c-Jun N-terminal kinase(JNK) in thermotherapy-induced apoptosis in human gastric cancer SGC-7901 cells.METHODS:Human gastric cancer SGC-7901 cells were cultured in vitro.Following thermo...
关键词:Thermotherapy Gastric cancer Apoptosis c-Jun N-terminal kinase Apoptosis-related protein 
Porcine placental peptides improve neuroblast proliferation and differentiation via enhancement of TrkB and BDNF levels in D-glatacose-induced mouse aging model被引量:1
《Journal of Chinese Pharmaceutical Sciences》2019年第10期739-748,共10页Xu Quan Caihong Gu Feng Yan Yaoyao Gao Lin Chen Rong Wei Bingchun Yan Rong Hul 
The University Natural Science Research major Project of Jiangsu Province(Grant No.16KJA310006)
Aging affects the nervous system as well as other organs.In our study,we aimed to study the pharmacological effects and mechanism of porcine placental peptides(PPP)in aging process,and to observe the changes of neurob...
关键词:Porcine placenta peptide ANTI-AGING Neuroblast proliferation and differentiation Apoptosis-related proteins BDNF/TrkB pathway 
Hawthorn Extract Alleviates Atherosclerosis through Regulating Inflammation and Apoptosis Related Factors: An Experimental Study被引量:18
《Chinese Journal of Integrative Medicine》2019年第2期108-115,共8页WANG Song-zi WU Min CHEN Ke-ji LIU Yue SUN Jing SUN Zhuo MA He LIU Long-tao 
Supported by the National Natural Science Foundation of China(No.81573821);General Financial Grant from China Postdoctoral Science Foundation(No.2016M600176);Special Financial Grant from China Postdoctoral Science Foundation(No.2017T100147)
Objective: To determine the effects of hawthorn extract on serum lipid levels, pathological changes in aortic atherosclerosis plaque, inflammatory factors, and apoptosis-related protein and mRNA expression in apolipop...
关键词:HAWTHORN extract ATHEROSCLEROSIS unstable PLAQUE INFLAMMATION factors apoptosis-related protein 
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