《Cancer Biology & Medicine》

作品数：900被引量：3600H指数：24
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《Cancer Biology & Medicine》
主办单位：China Anti-Cancer Association;Tianjin Medical University Cancer Institute and Hospital
最新期次：2025年2期更多>>
发文主题：CANCERIMMUNOTHERAPYBREAST_CANCERHEPATOCELLULAR_CARCINOMACHEMOTHERAPY更多>>
发文领域：医药卫生文化科学农业科学自动化与计算机技术更多>>
发文基金：国家自然科学基金国家重点基础研究发展计划天津市自然科学基金中国博士后科学基金更多>>
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A novel BaEVRless-LV packaging system for the production of lentiviral vectors for clinical-grade CAR-NK cell manufacturing
《Cancer Biology & Medicine》2025年第2期137-143,共7页Yinyin Zhang Minghuan Zhang Mengyuan Li Lihong Zong Qian Ye Wen Lei Wenhai Deng Wenbin Qian 
supported by grants from the Noncommunicable Chronic Diseases-National Science and Technology Major Project(Grant No.2023ZD0501300);Science Technology Department of Zhejiang Province(Grant No.2021C03117);National Natural Science Foundation of China(Grant No.82350104 and 82170219);Natural Science Foundation of Zhejiang Province,China(Grant No.LY23H080004 and LY24H080001);Medical Health Science and Technology Project of Zhejiang Provincial Health Commission(Grant No.2021KY199)。
Chimeric antigen receptor natural killer(CAR-NK)cell therapy is an alternative immunotherapy that provides robust tumor-eliminating effects without inducing life-threatening toxicities and graft-versus-host disease.CA...
关键词：LENTIVIRAL packaging VECTORS alternative immunotherapy chimeric antigen receptor natural system cell manufacturing process NOVEL 
Erianin inhibits the proliferation of lung cancer cells by suppressing mTOR activation and disrupting pyrimidine metabolism
《Cancer Biology & Medicine》2025年第2期144-165,共22页Lili Yan Yanfen Liu Yufei Huang Xiaoyu Sun Haiyang Jiang Jie Gu Jing Xia Xueni Sun Xinbing Sui 
supported by the National Natural Science Foundation of China(82104207);Natural Science Foundation of Zhejiang Province(LQ22H280001)。
Objective:Erianin has potential anticancer activities,especially against lung cancer.The specific mechanisms underlying the anticancer effects,including the molecular targets and signaling pathways in lung cancer,rema...
关键词：ERIANIN anti-cancer property lung cancer MTOR pyrimidine metabolism 
Improved treatment of colorectal liver metastases by early response evaluation and regimen adjustment:a prospective study of clinical functional MR-based modeling
《Cancer Biology & Medicine》2025年第2期166-176,共11页Wenhua Li Huan Zhang Zhe Gong Yue Li Zhiyu Chen Xiaodong Zhu Mingzhu Huang Zhe Zhang Chenchen Wang Lixin Qiu Qirong Geng Jinjia Chang Xiaoying Zhao Xuedan Sheng Wen Zhang Tong Tong Weijian Guo 
supported by the National Natural Science Foundation of China(Grant nos.82271946 and 82202101);Innovative Achievement Transformation of Shenkang MedicalEnterprise Integration(Grant no.SHDC2023CRD014)。
Objective:The aim of the study was to evaluate the feasibility of functional MR in predicting the clinical response to chemotherapy in patients with colorectal liver metastases(CLM).Methods:A total of 196 eligible pat...
关键词：Colorectal cancer liver metastases objective response rate MR 
Continuous R-DA-EDOCH alternated with high-dose Ara-C induces deep remission and overcomes high-risk factors in young patients with newly diagnosed mantle cell lymphoma
《Cancer Biology & Medicine》2025年第2期177-189,共13页Yi Wang Yuting Yan Dandan Shan Jiawen Chen Wei Liu Tingyu Wang Gang An WeiweiSui Wenyang Huang Wenjie Xiong Huimin Liu Qi Sun Huijun Wang Zhijian Xiao JianxiangWang Lugui Qiu Dehui Zou Shuhua Yi 
supported by grants from the National Natural Science Foundation of China(Grant Nos.82200215,82170193,and 82370197);the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(Grant No.2022-I2M-1-002)。
Objective:Our previous studies have indicated potentially higher proliferative activity of tumor cells in Chinese patients with mantle-cell lymphoma(MCL)than those in Western.Given the success and tolerability of R-DA...
关键词：Mantle cell lymphoma IMMUNOCHEMOTHERAPY high-risk factors minimal residual disease adverse events 
Updates to the 2024 CSCO advanced non-small cell lung cancer guidelines
《Cancer Biology & Medicine》2025年第2期77-82,共6页Jiale Wang Tianyu Qiu Shengxiang Ren 
supported by the Shanghai Excellent Academic Leader(Grant No.21XD1423200)。
In the past year,several advancements have been achieved in the treatment of advanced non-small cell lung cancer(NSCLC),particularly in the areas of immunotherapy and targeted therapy.These achievements have provided ...
关键词：csco guidelines targeted therapythese advanced non small cell lung cancer clinical oncologists IMMUNOTHERAPY ACCESSIBILITY economic considerations targeted therapy 
Antibody-drug conjugates in breast cancer:advances and prospects
《Cancer Biology & Medicine》2025年第2期83-92,共10页Zhiqiang Shi Yongjin Lu Qiuchen Zhao Yongsheng Wang Pengfei Qiu 
supported by grants from the National Natural Science Foundation of China(Grant No.81672638)。
The“Global Cancer Statistics Report 2022”estimates that there were approximately 20 million new cancer cases worldwide,including 9.7 million in females,of which 2.31 million were breast cancer cases1.Breast cancer i...
关键词：cancer related deaths breast cancer malignant tumor antibody drug conjugates global cancer statistics report 
Advances in gut microbiota-related treatment strategies for managing colorectal cancer in humans
《Cancer Biology & Medicine》2025年第2期93-112,共20页Bhaskar Roy Kunfeng Cao Chabungbam Orville Singh Xiaodong Fang Huanming Yang Dong Wei 
the Hangzhou Institute of Medicine(HIM)and Chinese Academy of Sciences for supporting work of this article。
Colorectal cancer(CRC)is a major contributor to global cancer-related mortality with increasing incidence rates in both developed and developing regions.Therefore,CRC presents a significant challenge to global health....
关键词：Gut microbiome colorectal cancer microbial biomarkers precision medicine 
Intra-tumoral bacteria in head and neck cancer:holistic integrative insight
《Cancer Biology & Medicine》2025年第2期113-136,共24页Yucheng Meng Jiaru Deng Weiwei Deng Zhijun Sun 
supported by grants from the National Natural Science Foundation of China(Grant nos.82472818 and 82103336);the Fundamental Research Funds for the Central Universities(Grant nos.2042024kf0021 and 2042022dx0003);the Natural Science Foundation of Wuhan(Grant no.2023020201020515)。
Intra-tumoral bacteria are pivotal in the initiation and progression of head and neck squamous cell carcinoma(HNSCC),exerting a significant influence on tumor cell biology,immune responses,and the tumor microenvironme...
关键词：Head and neck squamous cell carcinoma intra-tumoral bacteria tumor progression IMMUNITY therapy 
Elucidating the synergistic roles of CD4^(+)T and dendritic cells in antitumor immunity
《Cancer Biology & Medicine》2025年第1期1-5,共5页Xiubao Ren 
A recent publication by Espinosa-Carrasco et al.1has illuminated the critical roles of intratumoral immune triads-a unique cluster of CD4^(+)T cells,CD8^(+)T cells,and dendritic cells(DCs)-in mediating effective antit...
关键词：IMMUNITY TUMOR 
Integrating artificial intelligence into radiological cancer imaging:from diagnosis and treatment response to prognosis
《Cancer Biology & Medicine》2025年第1期6-13,共8页Sunyi Zheng Xiaonan Cui Zhaoxiang Ye 
funded by grants from the National Natural Science Foundation of China(Grant Nos.82171932 and 82302180);the Ministry of Science and Technology of China(Grant No.2024ZD0520002);the Chinese National Key Research and Development Project(Grant Nos.2021YFC2500402 and 2021YFC2500400);the National Health Commission Capacity Building and Continuing Education Center(Grant No.YXFSC2022JJSJ011);the Tianjin Key Medical Discipline(Specialty)Construction Project(Grant No.TJYXZDXK-010A);the Scientific Developing Foundation of Tianjin Education Commission(Grant No.2024KJ182).
Cancer poses a serious threat to human health worldwide and is a leading cause of death1.The analysis of radiological imaging is crucial in early detection,accurate diagnosis,effective treatment planning,and ongoing m...
关键词：DIAGNOSIS artificial TREATMENT 
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