MELOXICAM

作品数：24被引量：45H指数：4
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相关领域：医药卫生更多>>
相关作者：贾宝秀李珂曹明亮齐永秀董小锋更多>>
相关机构：泰山医学院山东大学华中科技大学武汉理工大学更多>>
相关期刊：《Genes & Diseases》《Journal of Pharmaceutical and Biopharmaceutical Research》《Neural Regeneration Research》《药物分析杂志》更多>>
相关基金：山东省科技攻关计划国家自然科学基金山东省科技发展计划项目更多>>
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Construction of meloxicam and bupivacaine co-delivery nanosystem based on the pathophysiological environment of surgical injuries for enhanced postoperative analgesia被引量：1
《Nano Research》2023年第12期13301-13308,共8页Mohan Li Yumiao He Zongran Liu Xu Ma Fengrun Sun Lijian Pei Chao Ma Hongju Liu Tianjiao Ji Yuguang Huang 
supported by the National High Level Hospital Clinical Research Funding(Nos.2022-PUMCH-B-006 and 2022-PUMCH-C-067);the National Natural Science Foundation of China(No.32271391);Beijing Natural Science Foundation(No.Z220022).
Besides peripheral nerve injury,the acute inflammation is one of the pathological features of tissues after surgery,which exacerbates the postoperative pain,especially in the first 48 h after the surgery.Multimodal an...
关键词：core–shell nanostructure multimodal analgesia co-delivery system postoperative pain management 
Neuroprotective effects of meloxicam on transient brain ischemia in rats:the two faces of anti-inflammatory treatments被引量：4
《Neural Regeneration Research》2023年第9期1961-1967,共7页Irene Fernández Ugidos Paloma González-Rodríguez María Santos-Galdiano Enrique Font-Belmonte Berta Anuncibay-Soto Diego Pérez-Rodríguez JoséManuel Gonzalo-Orden Arsenio Fernández-López 
supported by MINECO and FEDER funds:ref CPP2021-008855 and RTC-2015-4094-1,Junta de Castilla y León ref.LE025P1 7;Neural Therapies SL;ref.NTDev-01 (all to AFL and JMGO)。
The inflammato ry response plays an important role in neuroprotection and regeneration after ischemic insult.The use of non-ste roidal anti-inflammatory drugs has been a matter of debate as to whether they have benefi...
关键词：ANTI-INFLAMMATORIES ASTROCYTE axonal sprouting cylinder test DOUBLECORTIN focal brain ischemia glial scar inflammation neuroprotection new neuron generation transient stroke 
Integrated in silico formulation design of selfemulsifying drug delivery systems被引量：5
《Acta Pharmaceutica Sinica B》2021年第11期3585-3594,共10页Haoshi Gao Haoyue Jia Jie Dong Xinggang Yang Haifeng Li Defang Ouyang 
financially supported by the Science and Technology Development Fund(FDCT)of Macao(0029/2018/A1,China);the University of Macao Research Grants(MYRG2019-00041-ICMS,China);performed in part at the High-Performance Computing Cluster(HPCC)which is supported by Information and Communication Technology Office(ICTO)of the University of Macao,China。
The drug formulation design of self-emulsifying drug delivery systems(SEDDS)often requires numerous experiments,which are time-and money-consuming.This research aimed to rationally design the SEDDS formulation by the ...
关键词：Self-emulsifying drug delivery system Random forest Central composite design Molecular dynamic simulation MELOXICAM 
Co-nanoencapsulated meloxicam and curcumin improves cognitive impairment induced by amyloid-beta through modulation of cyclooxygenase-2 in mice被引量：1
《Neural Regeneration Research》2021年第4期780-786,共7页Maria Eduarda Ziani Gutierrez Anne Suély Pinto Savall Edina da Luz Abreu Kelly Ayumi Nakama Renata Bem Dos Santos Marina Costa Monteiro Guedes Daiana SilvaÁvila Cristiane Luchese Sandra Elisa Haas Caroline Brandão Quines Simone Pinton 
This study was supported by the Rio Grande do Sul Science Foundation(FAPERGS),grants#16/2551-0000207-0 and 16/0526-5(PRONUPEQ)(to SP);National Counsel of Technological and Scientific Development(CNPq)(Universal grants#423435/2016-7 and 460122/2014-2)and for student scholarships(to CL,SEH and DSÁ).
Alzheimer’s disease is a progressive brain disorder and complex mechanisms are involved in the physiopathology of Alzheimer’s disease.However,there is data suggesting that inflammation plays a role in its developmen...
关键词：Alzheimer’s disease CURCUMIN CYCLOOXYGENASE-2 lipid core nanocapsules MELOXICAM memory rats inflammation 
Postpartum meloxicam administration alters plasma haptoglobin, polyunsaturated fatty acid, and oxylipid concentrations in postpartum ewes
《Journal of Animal Science and Biotechnology》2020年第4期1047-1060,共14页Katie EOlagaray Barry J.Bradford Lorraine M.Sordillo Jeffery C.Gandy Laman K.Mamedova Turner H.Swartz Trey D.Jackson Emma K.Persoon Caitlin S.Shugart Curtis R.Youngs 
funded by a Let’s Grow grant through the American Sheep Industry。
Background: Postpartum inflammation is a natural and necessary response;however, a dysfunctional inflammatory response can be detrimental to animal productivity. The objective of this study was to determine the effect...
关键词：EICOSANOID Inflammation LACTATION Nonsteroidal anti-inflammatory drug Sheep 
The Effect of Delivery Method on the Pharmacokinetic Properties of Meloxicam in Pre-Weaned Dairy Calves with Diarrhea
《Open Journal of Veterinary Medicine》2020年第3期27-38,共12页Daniel Shock Steven Roche Denis Nagel Merle Olson 
The non-steroidal anti-inflammatory drug meloxicam is commonly used as adjunct therapy for neonatal calf diarrhea to control pain and inflammation. The objective of this study was to compare the pharmacokinetics of me...
关键词：MELOXICAM DAIRY CALVES Pharmacokinetics DIARRHEA ANTI-INFLAMMATORY 
Potential role of the compound Eucommia bone tonic granules in patients with osteoarthritis and osteonecrosis: A retrospective study被引量：2
《World Journal of Clinical Cases》2020年第1期46-53,共8页Cheng-Xia Hu Ke-Yao Hu Jian-Feng Wang 
BACKGROUND Osteoarthritis is a major source of pain,disability,and socioeconomic cost worldwide.Osteonecrosis is a disabling disorder that frequently occurs in the younger population aged from 20-50 years.The compound...
关键词：OSTEOARTHRITIS OSTEONECROSIS Eucommia PATIENTS MELOXICAM Drug 
Spectroscopic study on the mechanism of meloxicam and α-amylase
《Journal of Pharmaceutical and Biopharmaceutical Research》2019年第1期28-35,共8页Xu Cheng Baosheng Liu Hongcai Zhang 
In order to explore the mechanism of action of meloxicam and α-amylase. The interaction between the rheumatoid arthritis drug meloxicam and α-amylase was studied by fluorescence spectroscopy, synchronous fluorescenc...
关键词：DRUG protein fluorescence analysis CONFORMATION molecular DOCKING BINDING rate 
Evaluation on monoamine neurotransmitters changes in depression rats given with sertraline, meloxicam or/and caffeic acid被引量：6
《Genes & Diseases》2019年第2期167-175,共9页Dan Huang Lu Zhang Jun-qing Yang Ying Luo Ting Cui Ting-ting Du Xin-hui Jiang 
supported by pharmacy school of Chongqing Medical University.This research work was financially supported by Research Fund of Chongqing Science&Technology Commission(No:cstc2013jcyjA10040);Research Start-up Fund of Pharmacy School of Chongqing Medical University.
Inflammation drives the development of depression and may affect neurotransmitters and thus neurocircuits increase the risk of depression.To investigate the influence of inhibition of inflammatory pathways on the biog...
关键词：AA-COX-2/5-LO inflammatory pathways Bioamine neurotransmitters Caffeic acid Depression rat MELOXICAM SERTRALINE 
Using organotypic hippocampal slice cultures to gain insight into mechanisms responsible for the neuroprotective effects of meloxicam: a role for gamma aminobutyric and endoplasmic reticulum stress
《Neural Regeneration Research》2019年第1期65-66,共2页Elisa Landucci Irene L.Llorente Berta Anuncibay-Soto Domenico E.Pellegrini-Giampietro Arsenio Fernández-López 
supported by the Spanish Ministerio de Economia y Competitividad(MINECO);co-financed with FEDER funds ‘‘una manera de hacer Europa"(reference RTC-2015-4094-1);Junta de Castilla y León(reference LE025P17);Neural Therapies SL(reference NT-Dev01)
This perspective aims to put into context the recent article by Landucci et al.(2018)on mechanisms involved in the neuroprotective effects of meloxicam on an organotypic hippocampal slice cultures(OHSCs)model.In vitro...
关键词：GAMMA 文化 海马 机制 应力 蜂窝 环境学习 胃 
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