MEGAKARYOCYTE

作品数：17被引量：20H指数：2
导出分析报告
相关领域：医药卫生更多>>
相关机构：中国医学科学院血液病医院(血液学研究所)更多>>
相关期刊：《中国生物学文摘》《Chinese Journal of Integrative Medicine》《Oncology and Translational Medicine》《Chinese Medical Journal》更多>>
相关基金：国家自然科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Versatility of megakaryocytes in homeostasis and disease
《Blood Science》2024年第4期22-26,共5页Daosong Wang Jiayi Xie Meng Zhao 
supported in part by the National Key Research and Development Program of China(2022YFA1104100);the National Natural Science Foundation of China(82325002).
Megakaryocytes(MKs)constitute a small portion of bone marrow cells and are primarily responsible for producing platelets,which are essential for hemostasis and wound healing.Recent studies have revealed that MKs and p...
关键词：Aging Hematopoietic stem cell Immune responses MEGAKARYOCYTE NICHE PLATELET 
Immunological face of megakaryocytes
《Frontiers of Medicine》2024年第6期988-1001,共14页Yueying Li Kunying Chen Qian-Fei Wang 
supported by Beijing Natural Science Foundation(No.JQ21024);the National Natural Science Foundation of China(Nos.82350004,82130008 and 82170125);the Youth Innovation Promotion Association,Chinese Academy of Sciences(No.Y2021037);Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences(No.CI2023C027YL).
Megakaryocytes(MKs),which are traditionally known for their role in platelet production,are now emerging as unique immune cells with diverse capabilities.They express immune receptors,participate in pathogen recogniti...
关键词：MEGAKARYOCYTE PLATELET IMMUNE inflammation HETEROGENEITY 
MXRA7 is involved in megakaryocyte differentiation and platelet production
《Blood Science》2023年第3期160-169,共10页Zhenjiang Sun Benfang Wang Ying Shen Kunpeng Ma Ting Wang Yiqiang Wang Dandan Lin 
supported by grants from the National Natural Science Foundation of China(81600076,81271050,82070186);Suzhou Science and Technology Program Project(SKY2022043);the Innovation special project of science and technology of Jiangyin(JY0603A021014210012).
Matrix remodeling is a critical process in hematopoiesis.The biology of MXRA7,as a matrix remodeling associated gene,has still not been reported in hematopoietic process.Public databases showed that MXRA7 expressed in...
关键词：DIFFERENTIATION MEGAKARYOCYTES MXRA7 PLATELET 
Abivertinib inhibits megakaryocyte differentiation and platelet biogenesis
《Frontiers of Medicine》2022年第3期416-428,共13页Jiansong Huang Xin Huang Yang Li Xia Li Jinghan Wang Fenglin Li Xiao Yan Huanping Wang Yungui Wang Xiangjie Lin Jifang Tu Daqiang He Wenle Ye Min Yang Jie Jin 
supported by grants from National Natural Science Foundation of China(Nos.82070118 and 81820108004)and the Zhejiang Provincial Natural Science Foundation of China(Nos.LY 20H080008 and Y 19H080009).
Abivertinib,a third-generation tyrosine kinase inhibitor,is originally designed to target epidermal growth factor receptor(EGFR)-activating mutations.Previous studies have shown that abivertinib has promising antitumo...
关键词：abivertinib Btk inhibitor PLATELET MEGAKARYOCYTE MEGAKARYOPOIESIS thrombopoiesis 
Ultrastructural alterations of megakaryocytes in thrombocytopenia:A review of 43 cases被引量：1
《Blood Science》2021年第4期107-112,共6页Brian Eyden Yong-Xin Ru Shu-Xu Dong Jing Liu Xiao-Fan Liu 
Thrombocytopenia is a frequent occurrence in a variety of hematopoietic diseases;however,the details of the mechanism leading to low platelet count remain elusive.Megakaryocytes are a series of progenitor cells respon...
关键词：Blood disease MEGAKARYOCYTE PLATELET THROMBOCYTOPENIA ULTRASTRUCTURE 
Megakaryocyte aplastic thrombocytopeniaafter CAR T-cell therapy in a patient withmultiple myeloma:A case report被引量：1
《Oncology and Translational Medicine》2021年第1期45-47,共3页Shangqin Liu Chengsi Gui 
Chimeric antigen receptor(CAR)T-cell therapy is an effective new treatment strategy for hematologic malignancies.The success of CAR T-cell therapy in treating leukemia and lymphoma has promoted its development for mul...
关键词：megakaryocyte aplastic thrombocytopenia chimeric antigen receptor(CAR)T cell therapy multiple myeloma case report 
HOXC4 up-regulates NF-κB signaling and promotes the cell proliferation to drive development of human hematopoiesis, especially CD43+ cells被引量：1
《Blood Science》2020年第4期117-128,共12页Jiahui Zeng Wencui Sun Jing Chang Danying Yia Lijiao Zhu Yonggang Zhang Xu Pan Ya Zhou Mowen Lai Guohui Bian Qiongxiu Zhou Jiaxin Liu Bo Chen FengMa 
This work was supported by awards from the CAMS Initiatives for Innovative Medicine(2016-I2M-1-018 to F.Ma and 2017-I2M-3-021 to J.X.Liu);Sichuan Provincial Science and Technology Department Key R&D projects(020YFSY0023 to B.Chen);the Chengdu Science and Technology Project-Technology Innovation R&D(2018-YF05-01341-SN to B.Chen).
The hematopoietic function of HOXC4 has not been extensively investigated.Our research indicated that induction of HOXC4 in co-culture system from D10 significantly promoted productions of most hematopoietic progenito...
关键词：CD43 Erythroid–megakaryocyte common progenitor(EMkP) HEMATOPOIESIS HOXC4 Human embryonic stem cells(hESCs) Inducible expression 
Effects of Panaxadiol Saponins Component as A New Chinese Patent Medicine on Proliferation,Differentiation and Corresponding Gene Expression Profile of Megakaryocytes被引量：11
《Chinese Journal of Integrative Medicine》2016年第1期28-35,共8页温伟为 孙馨 庄海峰 林筱洁 郑智茵 高瑞兰 尹利明 
Supported by National Natural Science Foundation of China(No.81373876);Zhejiang Provincial Natural Science Foundation(No.LY14H290004);Science and Technology Program of Zhejiang Province(No.2010C33098)
Objective： To investigate the effects of panaxadiol saponins component （PDS-C） isolated from total saponins of panax ginseng on proliferation, differentiation and corresponding gone expression profile of megakaryoc...
关键词：panaxadiol saponins MEGAKARYOCYTE gene expression profile PROLIFERATION DIFFERENTIATION 
Study on the induction and differentiation of megakaryocyte progenitor cell derived from umbilical cord blood被引量：1
《China Medical Abstracts(Internal Medicine)》2014年第2期119-119,共1页陈琳 
Objective To build a protocol of separation and induction of megakaryocytes derived from cord blood mononuclear cells.Methods Red blood cells were precipitated by hydroxyethyl starch(HES).Mononuclear cells were obtain...
关键词：hydroxyethyl PROGENITOR umbilical FICOLL INDUCTION cytokine starch precipitated inducing MONONUCLEAR 
Effects of human immunodeficiency virus on the erythrocyte and megakaryocyte lineages被引量：2
《World Journal of Virology》2013年第2期91-101,共11页Davide Gibellini Alberto Clò Silvia Morini Anna Miserocchi Cristina Ponti Maria Carla Re 
Supported by Funds from Fondazione Cassa di Risparmio Bologna,Italy,No.2006.0035;Fondazione del Monte di Bologna e Ravenna,Italy,No.376 bis;"AIDS projects"of the Italian Ministry of Health,No.40H5;Funds for Selected Research Topics of the University of Bologna and MURST 60%
Anaemia and thrombocytopenia are haematological disorders that can be detected in many human immunodeficiency virus(HIV)-positive patients during the development of HIV infection. The progressive decline of erythrocyt...
关键词：Human immunodeficiency virus Erythrocytes MEGAKARYOCYTES Haematopoietic PROGENITOR cells VIROLOGY 
全选清除导出
共2页<12>
检索报告 对象比较 聚类工具 使用帮助 返回顶部