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NEURITES: 作品数：17被引量：34H指数：3; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：甄晓光官孝群王毅超刘银坤宋后燕更多>>; 相关机构：复旦大学中国科学院上海生命科学研究院中南大学上海交通大学医学院附属仁济医院更多>>; 相关期刊：《Acta Pharmacologica Sinica》《Neural Regeneration Research》《International Journal of Ophthalmology(English edition)》《Chinese Medical Journal》更多>>; 相关基金：国家自然科学基金山西省自然科学基金北京市自然科学基金上海市卫生局资助项目更多>>

Modulation of the Nogo signaling pathway to overcome amyloid-β-mediated neurite inhibition in human pluripotent stem cell-derived neurites: 《Neural Regeneration Research》2025年第9期2645-2654,共10页Kirsty Goncalves Stefan Przyborski; supported by a BBSRC CASE training studentship,No.BB/K011413/1(to KG)。; Neuronal cell death and the loss of connectivity are two of the primary pathological mechanisms underlying Alzheimer's disease.The accumulation of amyloid-βpeptides,a key hallmark of Alzheimer's disease,is believed t...; 关键词：Alzheimer's disease induced pluripotent stem cell neurite outgrowth neuron NOGO Rho A ROCK stem cell three-dimensional culture

Direction Selectivityof TmY Neurites in Drosophila: 《Neuroscience Bulletin》2023年第5期759-773,共15页Yinyin Zhao Shanshan Ke Guo Cheng Xiaohua Lv Jin Chang Wei Zhou; supported by grants from the National Natural Science Foundation of China(61890950 and 31871027);Fundamental Research Funds for the Central Universities/HUST(2016YXMS034 and 2014TS015);the Director Fund of WNLO,and the China Postdoctoral Science Foundation(2015T80788).; The perception of motion is an important func-tion of vision.Neural wiring diagrams for extracting direc-tional information have been obtained by connectome recon-struction.Direction selectivity in Drosophila is thoug...; 关键词：Direction selectivity TmY-ds-Synaptic connection Two-photon calcium imaging DROSOPHILA

Dysregulated expression and distribution of Kif5αin neurites of wobbler motor neurons: 《Neural Regeneration Research》2023年第1期150-154,共5页Kilian Kürten Anne-Christin Gude Aimo Samuel Christian Epplen Jan Stein Carsten Theiss Veronika Matschke; supported by FoRUM–F976-20 (Ruhr-University Bochum)(to VM and CT); Impaired axonal transport has been observed in patients with amyotrophic lateral sclerosis(ALS)and in animal models,suggesting that transport proteins likely play a critical role in the pathological mechanism of ALS.D...; 关键词：amyotrophic lateral sclerosis cell culture KINESIN MITOCHONDRIA NEURODEGENERATION spinal cord TRANSPORT

Advanced diffusion magnetic resonance imaging in patients with Alzheimer’s and Parkinson’s diseases被引量：14: 《Neural Regeneration Research》2020年第9期1590-1600,共11页Koji Kamagata Christina Andica Taku Hatano Takashi Ogawa Haruka Takeshige-Amano Kotaro Ogaki Toshiaki Akashi Akifumi Hagiwara Shohei Fujita Shigeki Aoki; supported by research grants from the program for Brain/MINDS Beyond program from the Japan Agency for Medical Research and Development(AMED)under Grant Number JP18dm0307024(to KK);MEXT-Supported Program for the Private University Research Branding Project;ImPACT Program of Council for Science,Technology and Innovation(Cabinet Office,Government of Japan);JSPS KAKENHI Grant Number JP16K10327(to KK); The prevalence of neurodegenerative diseases is increasing as human longevity increases. The objective biomarkers that enable the staging and early diagnosis of neurodegenerative diseases are eagerly anticipated. It h...; 关键词：Alzheimer's disease biomarkers diffusional kurtosis imaging disease progression early diagnosis free-water imaging NEURITES neurite orientation dispersion and density imaging Parkinson's disease

Fabrication of extracellular matrix-coated conductive polypyrrolepoly(L-lactide)fiber-films and their synergistic effect with(nerve growth factor)/(epidermal growth factor) on neurites growth被引量：1: 《Chinese Chemical Letters》2020年第5期1141-1146,共6页Ximing Pu Xingxing Zhou Zhongbing Huang Guangfu Yin Xianchun Chen; supported by the National Natural Science Foundation of China(No.51273122);Sichuan Science and Technology Project(No.2018JY0535)。; Non-nerve cell-derived extracellular matrix(ECM)wa s coated on the aligned porous polypyrrole-poly(Llactide)(PPy-PLLA)fiber-films with the conductivity of^12 mS/m via L929 cells culture and lysing,resulting in^10%incr...; 关键词：Extracellular matrix Axonal growth Conducting PPy-PLLA fiber-film Nerve growth factor Epidermal growth factor Electrical stimulation

Stereotactic Injection of shRNA GSK-3β-AAV Promotes Axonal Regeneration after Spinal Cord Injury: 《Journal of Huazhong University of Science and Technology(Medical Sciences)》2016年第4期548-553,共6页左玉超熊南翔赵洪洋; supported by the National Natural Science Foundation of China(No.81371380); Evidence suggested that glycogen synthase kinase-3β（GSK-3β） is involved in Nogo-66 inhibiting axonal regeneration in vitro, but its effect in vivo was poorly understood. We showed that stereotactic injection of sh...; 关键词：NEURITES wound healing protein-serine-threonine kinases myelin proteins

Effect of Interleukin-1Beta (IL-1β) on the Cortical Neurons Survival and Neurites Outgrowth: 《Advances in Bioscience and Biotechnology》2016年第1期28-37,共10页Ebtesam M. Abd-El-Basset; Insults to the brain are known to cause a myriad of downstream effects, including the release of cytokines by astrocytes and resultant reactive gliosis. The author has examined effect of cytokine IL-1β on the surviva...; 关键词：Astrocytes IL-1Β Cell Culture Neuronal Survival Cytokines GLIOSIS

Blockade of transient receptor potential cation channel subfamily V member 1 promotes regeneration after sciatic nerve injury被引量：4: 《Neural Regeneration Research》2015年第8期1324-1331,共8页Fei Ren Hong Zhang Chao Qi Mei-ling Gao Hong Wang Xia-qing Li; supported by the National Natural Science Foundation of China,No.81171178;the Natural Science Foundation of Shanxi Province in China,No.2012011036-3;Scientific Research Foundation of Shanxi Province of China for the Returned Overseas Chinese Scholars,No.2013011054-2; The transient receptor potential cation channel subfamily V member 1（TRPV1） provides the sensation of pain（nociception）. However, it remains unknown whether TRPV1 is activated after peripheral nerve injury, or whe...; 关键词：nerve regeneration peripheral nerve regeneration transient receptor potential cation channel subfamily V member 1 capsaicin receptor vanilloid receptor TRPV1 antagonist nociceptor nerve crush injury Wallerian degeneration axon NSFC grant neurites neural regeneration

Effect of type-2 astrocytes on the viability of dorsal root ganglion neurons and length of neuronal processes: 《Neural Regeneration Research》2014年第2期119-128,共10页Chunling Fan Hui Wang Dan Chen Xiaoxin Cheng Kun Xiong Xuegang Luo Qilin Cao; supported by the NIH Foundation of the USA,No.R01 NS061975;the Natural Science Foundation of Hunan Province in China,No.11JJ6077; The role of type-2 astrocytes in the repair of central nervous system injury remains poorly un- derstood. In this study, using a relatively simple culture condition in vitro, type-2 astrocytes, differentiated from oli...; 关键词：nerve regeneration spinal cord injury OLIGODENDROCYTE oligodendrocyte precursor cells ASTROCYTES bone morphogenetic protein neurons NEURITES dorsal root ganglion NIH grant neuralregeneration

Neurotrophins differentially stimulate the growth of cochlear neurites on collagen surfaces and in gels: 《Neural Regeneration Research》2013年第17期1541-1550,共10页Joanna Xie Kwang Pak Amaretta Evans Andy Kamgar-Parsi Stephen Fausti Lina Mullen Allen Frederic Ryan; supported by grants from the Research Service of the United States Veterans Administration (to Allen Frederic Ryan and Stephen Fausti);the National Institute of Health/National Institute on Deafness and Other Communication Disorders (to Allen Frederic Ryan);the National Institute of Health Summer Research Program (to Joanna Xie);the Deafness Research Foundation (to Lina Mullen);the National Organization for Hearing Research (to Lina Mullen); The electrodes of a cochlear implant are located far from the surviving neurons of the spiral ganglion, which results in decreased precision of neural activation compared to the normal ear. If the neurons could be ind...; 关键词：neural regeneration peripheral nerve injury cochlear implant inner ear neuron neurite guidance NEUROTROPHIN extracellular matrix collagen gel grants-supported paper NEUROREGENERATION

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