POSTTRANSCRIPTIONAL

作品数:15被引量:66H指数:4
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The discovery of tiny RNAs that have crucial roles
《Science China(Life Sciences)》2025年第4期1183-1185,共3页Shouhong Guang Mo-Fang Liu 
On October 7, the Nobel Assembly at Sweden's Karolinska Institute announced the awarding of the 2024 Nobel Prize in Physiology or Medicine to American scientists Victor Ambros and Gary Ruvkun for their discovery of mi...
关键词:tiny RNAs MICRORNAS posttranscriptional gene regulation nobel assembly 
Interplay of RNA-binding proteins controls germ cell development in zebrafish
《Journal of Genetics and Genomics》2024年第9期889-899,共11页De-Li Shi 
The specification of germ cells in zebrafish mostly relies on an inherited mechanism by which localized maternal determinants,called germ plasm,confer germline fate in the early embryo.Extensive studies have partially...
关键词:GERMPLASM Primordialgerm cell Germlinestem cell GAMETOGENESIS ZEBRAFISH RNA-binding protein Posttranscriptional gene expression Translational activation and repression 
Metastasis-associated lung adenocarcinoma transcript 1 molecular mechanisms in gastric cancer progression被引量:1
《World Journal of Gastrointestinal Oncology》2023年第9期1520-1530,共11页Daniel Mateus de Oliveira Batista Jessica Manoelli Costa da Silva Carolina de Oliveira Gigek Marilia de Arruda Cardoso Smith Paulo Pimentel de Assumpcao Danielle Queiroz Calcagno 
Gastric cancer(GC)remains among the most common cancers worldwide with a high mortality-to-incidence ratio.Accumulated evidence suggests that long noncoding RNAs(lncRNAs)are involved in gastric carcinogenesis.These tr...
关键词:Long noncoding RNA Gastric carcinogenesis Transcriptional levels Posttranscriptional levels Prognostic biomarker Liquid biopsy 
miR-199-5p regulates spermiogenesis at the posttranscriptional level via targeting Tekt1 in allotriploid crucian carp被引量:2
《Journal of Animal Science and Biotechnology》2022年第5期1373-1385,共13页Shengnan Li Qiubei Wang Lu Huang Siyu Fan Ting Li Yuqing Shu Chun Zhang Yi Zhou Qingfeng Liu Kaikun Luo Min Tao Shaojun Liu 
supported by the National Natural Science Foundation of China(Grant No.31872551);Laboratory of Lingnan Modern Agriculture Project(Grant No.NT2021008);the Natural Science Foundation of Hunan Province for Distinguished Young Scholars(Grant No.2020JJ2022);Hunan Provincial Innovation Foundation for Postgraduate(Grant No.CX20200480);the earmarked fund for China Agriculture Research System(Grant No.CARS-45);the Key Research and Development Program of Hunan Province(Grant No.2020NK2016);111 Project(D20007).
Background:Sperm abnormalities are one of the primary factors leading to male sterility,but their pathogenesis is still unclear.Although miRNAs are suggested to exert important roles in the regulation of spermatogenes...
关键词:Allotriploid crucian carp miR-199-5p Sperm abnormalities Sperm flagella SPERMIOGENESIS Tekt1 
On or Off:Life-Changing Decisions Made by Vibrio cholerae Under Stress
《Infectious Microbes & Diseases》2020年第4期127-135,共9页Yitian Zhou Zachariah LLee Jun Zhu 
NIH grants(Grant numbers:AI120489,AI157106 and AI137283).
Vibrio cholerae,the causative agent of the infectious disease,cholera,is commonly found in brackish waters and infects human hosts via the fecal-oral route.V.cholerae is a master of stress resistance as V.cholerae’s ...
关键词:posttranscriptional modification stress responses transcriptional regulation Vibrio cholerae VIRULENCE 
Marking RNA:m^6A writers,readers,and functions in Arabidopsis被引量:15
《Journal of Molecular Cell Biology》2019年第10期899-910,共12页Marlene Reichel Tino Koster Dorothee Staiger 
N^6-methyladenosine(m^6A)emerges as an important modification in eukaryotic mRNAs.m^6A has first been reported in 1974,and its functional significance in mammalian gene regulation and importance for proper development...
关键词:ARABIDOPSIS m^6A mRNA INTERACTOME POSTTRANSCRIPTIONAL RNA-BINDING protein 
Human antigen R mediated post-transcriptional regulation of inhibitors of apoptosis proteins in pancreatic cancer被引量:1
《World Journal of Gastroenterology》2019年第2期205-219,共15页Ausra Lukosiute-Urboniene Aldona Jasukaitiene Giedre Silkuniene Vidmantas Barauskas Antanas Gulbinas Zilvinas Dambrauskas 
AIM To determine the association of human antigen R(HuR) and inhibitors of apoptosis proteins(IAP1, IAP2) and prognosis in pancreatic cancer.METHODS Protein and mRNA expression levels of IAP1, IAP2 and HuR in pancreat...
关键词:PANCREATIC cancer Inhibitors of apoptosis PROTEINS HUMAN ANTIGEN R POSTTRANSCRIPTIONAL regulation 
Regulation of RNA binding proteins in trypanosomatid protozoan parasites
《World Journal of Biological Chemistry》2016年第1期146-157,共12页María Albertina Romaniuk Gabriela Cervini Alejandro Cassola 
Supported by The Agencia Nacional de Promoción Científica y Tecnológica(ANPCyT)to Alejandro Cassola
Posttranscriptional mechanisms have a critical role in the overall outcome of gene expression. These mechanisms are especially relevant in protozoa from the genus Trypanosoma, which is composed by death threatening pa...
关键词:TRYPANOSOMA POSTTRANSCRIPTIONAL gene expression RIBONUCLEOPROTEIN complexes RNA-BINDING protein Developmental REGULATION Sleeping sickness Posttranslational modification Phosphorylation CHAGAS disease 
Extracellular microRNAs from the epididymis as potential mediators of cell-to-cell communication被引量:5
《Asian Journal of Andrology》2015年第5期730-736,I0006-I0007,共9页Clemence Belleannee 
Ribonucleic acid (RNA) was previously thought to remain inside cells as an intermediate between genes and proteins during translation. However, it is now estimated that 98% of the mammalian genomic output is transcr...
关键词:Dicer EPIDIDYMIS exocrine factors extracellular vesicles intercellular communication MICRORNAS paracrine regulation posttranscriptional gene regulation seminal plasma spermatozoa 
1,25-Dihydroxyvitamin D_(3) effects on the regulation of the insulin receptor gene in the hind limb muscle and heart of streptozotocin-induced diabetic rats
《American Journal of Molecular Biology》2013年第2期87-97,共11页Consuelo Calle Begona Maestro Moisés García-Arencibia 
This work was supported by research Funds from the Ministerio de Ciencia e Innovación(SAF2009-12671).
In the present study, we examine the effects of the treatment with 1,25-dihydroxyvitamin D3 [150 IU/Kg (3.75 μg/Kg) once a day, for 15 days] to non-diabetic and streptozotocin-induced diabetic rats. The results indic...
关键词:1 25-Dihydroxyvitamin D3 Streptozotocin-Induced Diabetic Rats Hind Limb Muscle HEART Rat Insulin Receptor Gene Computer Analysis Vitamin D Response Element Posttranscriptional Processes. 
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