Chagas heart disease(CHD)affects approximately 30%of patients chronically infected with the protozoa Trypanosoma cruzi.CHD is classified into four stages of increasing severity according to electrocardiographic,echoca...
Supported by National Science and Technology Project(No.2018ZX10101002);National Key Research and Development Program of China(Grant No.2016YFC1202000);Guangxi Natural Science Foundation Program(2018GXNSFAA 294092).
Summary What is already known on this topic?Triatoma rubrofasciata is a potential vector that can transmit American trypanosomiasis and was widely recorded in South of China.What is added by this report?Because of the...
Background:Chagas disease is endemic in Latin America and still represents an important public health problem in the region.Chronic cardiomyopathy is the most significant chronic form due to its association with morbi...
supported by the National Natural Science Foundation of China(No.81470571/81300230)
Background Chronic Chagas cardiomyopathy(CCM)is an infectious disease which could lead to severe dilated cardiomyopathy. Intensive efforts have been made to elucidate the pathogeny,but the molecular mechanisms of CCM ...
Supported by The Agencia Nacional de Promoción Científica y Tecnológica(ANPCyT)to Alejandro Cassola
Posttranscriptional mechanisms have a critical role in the overall outcome of gene expression. These mechanisms are especially relevant in protozoa from the genus Trypanosoma, which is composed by death threatening pa...
The Education for Health at PET Work Program (PET-Health) is focused on education as a pre-supposition. Actions are directed towards to the integration of service-learning and community. Interdisciplinary principle is...
Background: Chagas disease is still a public health problem because of the remaining high prevalence, the expansion of the disease into developed countries and the re-emergences by oral transmission outbreaks. Chagas ...
There is some published evidence suggesting micro vascular endothelial dysfunction and dysautonomia involvement in Chagas disease in association with cardiomyocyte changes favoring disease progression. The combined tr...
Chagas cardiomyopathy still remains a challenging problem that is responsible for high morbidity and mortality in Central and Latin America. Chagas disease disrupts blood microcirculation via various autoimmune mechan...