云南高校图书馆联盟文献共享服务平台- DEFERIPRONE

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Inhibitory effect of ferroptosis inhibitor toxicity induced by cobalt nanoparticles through reactive oxygen species: 《中国组织工程研究》2025年第34期7310-7317,共7页Wang Chen Zhang Weinan Shen Jining Liu Fan Yuan Jishan Liu Yake; 国家自然科学基金面上项目(82172519),项目负责人:刘璠;国家自然科学基金青年科学基金项目(82002282),项目负责人:刘雅克。; BACKGROUND:Soft tissue damage induced by cobalt nanoparticles is currently the most noticeable complication in patients with artificial joint prostheses.Therefore,an effective therapeutic strategy is needed to limit t...; 关键词：cobalt nanoparticle ARTHROPLASTY ferroptosis inhibitor ferroptosis reactive oxygen species DEFERIPRONE metal implant detoxify nanobiomedicine pathway FIBROBLAST

New developments and controversies in iron metabolism and iron chelation therapy被引量：5: 《World Journal of Methodology》2016年第1期1-19,共19页Christina N Kontoghiorghe George J Kontoghiorghes; Iron is essential for all organisms including microbial,cancer and human cells. More than a quarter of the human population is affected by abnormalities of iron metabolism, mainly from iron deficiency and iron overloa...; 关键词：IRON metabolism IRON CHELATION therapy DEFERIPRONE DEFEROXAMINE DEFERASIROX IRON diseases Medical journals CONTROVERSIES

Transition of Thalassaemia and Friedreich ataxia from fatal to chronic diseases被引量：2: 《World Journal of Methodology》2014年第4期197-218,共22页Annita Kolnagou Christina N Kontoghiorghe George J Kontoghiorghes; Thalassaemia major(TM) and Friedreich's ataxia(FA) are autosomal recessive inherited diseases related to the proteins haemoglobin and frataxin respectively. In both diseases abnormalities in iron metabolism is the mai...; 关键词：THALASSAEMIA Friedreich ataxia Prenatal diagnosis SURVIVAL Chelation therapy DEFERIPRONE DEFEROXAMINE Cyprus

World health dilemmas: Orphan and rare diseases, orphan drugs and orphan patients被引量：1: 《World Journal of Methodology》2014年第3期163-188,共26页Christina N Kontoghiorghe Nicholas Andreou Katerina Constantinou George J Kontoghiorghes; According to global annual estimates hunger/malnutrition is the major cause of death(36 of 62 million). Cardiovascular diseases and cancer(5.44 of 13.43 million) are the major causes of death in developed countries, w...; 关键词：World health issues Global DISEASES Orphandrugs ORPHAN DISEASES Rare DISEASES ORPHAN PATIENTS THALASSAEMIA DEFERIPRONE DEFERASIROX Deferoxamine Iron overload

Deferiprone获准用于治疗体内铁过量: 《药学进展》2011年第12期576-576,共1页邢爱敏; 美国FDA近日批准ApoPharma公司开发的deferiprone（商品名：Ferriprox）上市,用于治疗既往接受螯合剂治疗无效的地中海贫血患者因输血导致的铁过量。; 关键词：DEFERIPRONE 铁过量地中海贫血

Deferiprone对染铝小鼠肾脏ATP酶、黄嘌呤氧化酶的影响被引量：1: 《食品与药品》2011年第11期388-391,共4页赵慧娟李宁刘萍; 目的探讨1,2-二甲基-3-羟基-4-吡啶酮(DFP)对AlCl3染毒小鼠肾脏三磷酸腺苷酶(ATPase)、黄嘌呤氧化酶(xanthine oxidase,XO)的影响。方法 50只健康昆明种小鼠,按体重随机分为5组:阴性对照组、铝染毒组、DFP低、中、高剂量组。小鼠经三氯...; 关键词：铝 1 2-二甲基-3-羟基-4-吡啶酮肾脏腺苷三磷酸酶黄嘌呤氧化酶小鼠

Liver iron content determination by magnetic resonance imaging被引量：16: 《World Journal of Gastroenterology》2010年第13期1587-1597,共11页Konstantinos Tziomalos Vassilios Perifanis; Accurate evaluation of iron overload is necessary to establish the diagnosis of hemochromatosis and guide chelation treatment in transfusion-dependent anemia. The liver is the primary site for iron storage in patients...; 关键词：Thalassemia major Iron overload Magnetic resonance imaging Liver HEMOCHROMATOSIS DESFERRIOXAMINE DEFERIPRONE DEFERASIROX Thalassemia inter media Myelodysplastic syndromes

Deferiprone protects the isolated atria from cardiotoxicity induced by doxorubicin被引量：1: 《Acta Pharmacologica Sinica》2006年第10期1333-1339,共7页Ling-jie XU Liang JIN Hong PAN Ao-zhen ZHANG Gang WEI Ping-ping LI Wei-yue LU; Aim： To investigate the effects of deferiprone on doxorubicin-induced cardiotoxicity and determine its protection on cardiac contractility in vivo at tissue level. Methods： Spontaneously-beating isolated atria from ...; 关键词：DEFERIPRONE DOXORUBICIN CARDIOTOXICITY cardiac protection isolated atria

去铁胺和deferiprone的临床研究进展被引量：5: 《国外医学（儿科学分册）》2005年第1期40-42,共3页夏婷方建培; 铁螯合剂的应用能改善铁超负荷疾病患儿的生活质量 ,延长生存时间 ,尤其是近 10年来新型口服制剂的开发和应用 ,使其疗效得到了进一步提高。该文对已在临床应用的两种铁螯合剂去铁胺和deferiprone的药理作用机制、临床应用、药物毒副作...; 关键词：铁螯合剂 Β地中海贫血

β—地中海贫血的铁过量治疗药——Deferiprone: 《国外新药介绍》2000年第1期26-28,共3页梁茵; 关键词：Β-地中海贫血铁过量药物治疗 DEFERIPRONE

DEFERIPRONE