DEOXYURIDINE

作品数：17被引量：48H指数：4
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相关领域：医药卫生更多>>
相关作者：徐石海廖小建刘鋌赵春礼王元身更多>>
相关机构：暨南大学空军军医大学（第四军医大学）北京市耳鼻咽喉科研究所首都医科大学更多>>
相关期刊：《Science China Chemistry》《World Journal of Gastroenterology》《Journal of Pharmacy and Pharmacology》《Chinese Medical Journal》更多>>
相关基金：国家自然科学基金广东省自然科学基金广东省重大科技专项天津市自然科学基金更多>>
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5-Bromo-2'-deoxyuridine labeling:historical perspectives,factors infiuencing the detection,toxicity,and its implications in the neurogenesis
《Neural Regeneration Research》2024年第2期302-308,共7页Joaquín Martí-Clúa 
The halopyrimidine 5-bromo-2′-deoxyuridine(BrdU)is an exogenous marker of DNA synthesis.Since the introduction of monoclonal antibodies against BrdU,an increasing number of methodologies have been used for the immuno...
关键词：5-bromo-2′-deoxyuridine adult neurogenesis human adult neurogenesis LABELING pitfalls prenatal neurogenesis proliferation S-PHASE suturing S-phase TOXICITY 
Unexpected BrdU inhibition on astrocyte-to-neuron conversion被引量：2
《Neural Regeneration Research》2022年第7期1526-1534,共9页Tao Wang Jian-Cheng Liao Xu Wang Qing-Song Wang Kai-Ying Wan Yi-Yi Yang Qing He Jia-Xuan Zhang Gong Chen Wen Li 
supported by the Natural Science Foundation of Guangdong Province of China,Nos.2021A1515011237(to WL),2020A1515010854(to QSW);the National Natural Science Foundation of China,Nos.U1801681(to GC),31701291(to WL);the Guangdong Province Science and Technology Planning Project of China,No.2018B030332001(to GC)。
5-Bromo-2′-deoxyuridine(BrdU)is a halogenated pyrimidine that can be incorporated into newly synthesized DNA during the S phase of the cell cycle.BrdU is widely used in fate-mapping studies of embryonic and adult neu...
关键词：5-bromo-2′-deoxyuridine NeuroD1 astrocyte-to-neuron conversion reprogramming neural regeneration reactive astrocytes neurons lineage tracing fate mapping neural stem cell 
Intermolecular hydrogen-bond interaction to promote thermoreversible 2'-deoxyuridine-based AIE-organogels被引量：2
《Chinese Chemical Letters》2021年第4期1363-1366,共4页Xuan Zhao Long Zhao Qiuyun Xiao Hai Xiong 
supported by the Science and Technology Innovation Commission of Shenzhen,China(Nos.KQJSCX20180328095517269 and JCYJ20170818143131729)。
Fluorescent supramolecular nucleoside-based organogels or hydrogels have attracted increasing attention owing to their tunable stability,drug delivery,tissue engineering,and inherent biocompatibility for applications ...
关键词：Supramolecular ORGANOGEL Aggregation-induced emission NUCLEOSIDE Click chemistry 
Lithium promotes proliferation and suppresses migration of Schwann cells被引量：6
《Neural Regeneration Research》2020年第10期1955-1961,共7页Xiao-Kun Gu Xin-Rui Li Mei-Ling Lu Hui Xu 
supported by the National Natural Science Foundation of China,No.81970820(to HX)
Schwann cell proliferation,migration and remyelination of regenerating axons contribute to regeneration after peripheral nervous system injury.Lithium promotes remyelination by Schwann cells and improves peripheral ne...
关键词：5-ethynyl-2′-deoxyuridine Cell Counting Kit-8 cell viability LITHIUM MIGRATION peripheral nerve PROLIFERATION regeneration Schwann cell wound healing assay 
Synthesis and Photophysical Properties of Conjugates of Green Fluorescent Protein (GFP) Chromophore and 2'-Deoxy-Uridine Developed as Labelled Building Blocks for Oligonucleotide Probes
《Journal of Pharmacy and Pharmacology》2019年第9期510-519,共10页Abed Saady Bilha Fischer 
Fluorescent probes with high signal/background ratio are needed for hybridization assays. Hence, the chromophore of green fluorescent protein (GFP), 4-hydroxybenzylidene-imidazolinone (HBI), was targeted as a potentia...
关键词：INTERCALATOR GFP 2'-deoxyuridine INTERCALATOR CONJUGATES 
Short-term environmental enrichment exposure induces proliferation and maturation of doublecortin-positive cells in the prefrontal cortex被引量：5
《Neural Regeneration Research》2014年第3期318-328,共11页Chunling Fan Mengqi Zhang Lei Shang Ngobe Akume Cynthia Zhi Li Zhenyu Yang Dan Chen Jufang Huang Kun Xiong 
the National Natural Science Foundation of China,No.30900773;the Natural Science Foundation of Hunan Province in China,No.11JJ2020;Young Teachers Training Program of University of Hunan Province
Previous studies have demonstrated that doublecortin-positive immature neurons exist pre- dominantly in the superficial layer of the cerebral cortex of adult mammals such as guinea pigs, and these neurons exhibit very...
关键词：nerve regeneration NEUROGENESIS prefrontal cortex NEOCORTEX guinea pig doublecortinprotein cell proliferation neurons 5-bromodeoxyuridine NSFC grant neural regeneration 
Nanomolar concentration of alpha-synuclein enhances dopaminergic neuronal survival via Akt pathway被引量：2
《Neural Regeneration Research》2013年第35期3269-3274,共6页Ji-Young Kim Beom Seok Jeon Han-Joon Kim Tae-Beom Ahn 
supported by the Seoul National University Hospital(SNUH)Research Fund,No.03-2010-0240
Although alpha-synuclein is generally thought to have a pathological role in Parkinson＇s disease, accumulative evidence exists that alpha-synuclein has a neuroprotective effect. The aim of this study was to evaluate ...
关键词：neural regeneration ALPHA-SYNUCLEIN neuronal survival nanomolar extracellular phosphorylatedAkt SH-SY5Y cell neuronal differentiation proliferation DOPAMINERGIC 5-bromo-2＇-deoxyuridine grants-supported paper NEUROREGENERATION 
南海橙色手指海绵化学成分研究被引量：1
《中国药学杂志》2012年第22期1799-1802,共4页许文杰 华怀杰 郑加林 廖小建 徐石海 
国家自然科学基金资助项目(21172094);广东省重大科技专项(2011A080504007)
目的研究橙色手指海绵(Axinella sp.)的化学成分。方法采用硅胶柱色谱、Sephadex LH-20和反相半制备HPLC等方法分离化合物,根据波谱数据确定其结构。结果从橙色手指海绵分离得到10个化合物,鉴定为:cyclo-(Val-Pro)(1)、cy-clo-(Tyr-Pro)...
关键词：海绵 橙色手指海绵 结构鉴定 spongothymidine spongouridine 2'-deoxyuridine 
5-Ethynyl-2′-deoxyuridine as a molecular probe of cell proliferation for high-content siRNA screening assay by “click” chemistry被引量：7
《Science China Chemistry》2011年第11期1702-1710,共9页CHEN MiaoJuan QU DeZhong CHI WeiLin WANG Wei REN XiaoShuai CONG ShuJie LIANG PeiZhou FENG ShiPeng ZHANG BiLiang 
supported by the National Natural Science Foundation of China (30870535 and 90913017) (B. Zhang) ;Introduced Innovative R&D Team Program of Guangdong Province (Gene Silencing Technology and Therapeutics)
Labelling and identification of proliferating cells is important for the study of physiological or pathological processes in high-content screening (HCS) assays. Here we describe ethynyl deoxyuridine (EdU) as a biomar...
关键词：molecular probe SIRNA miRNA ＂click＂ chemistry 
Proliferation and Differentiation of Duct Epithelial Cells after Partial Pancreatectomy in Rats被引量：3
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2006年第5期567-569,共3页刘涛 王春友 万赤丹 熊炯炘 周峰 
This project was supported by a grant from National Natural Sciences Founcation of China (No. 30170911).
The proliferation and differentiation of pancreatic duct epithelial cells in remnant pancreas during regeneration after partial pancreatectomy in rats were studied, and the source of pancreatic stem cells was characte...
关键词：PANCREAS stem cells REGENERATION 5-bromo-2＇-deoxyuridine RATS 
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