SULFASALAZINE

作品数：25被引量：120H指数：6
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相关作者：宋玉梅王锡森熊仁根黄喆更多>>
相关机构：南京大学中国医科大学更多>>
相关期刊：《World Journal of Dermatology》《Chinese Journal of Integrative Medicine》《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》更多>>
相关基金：国家自然科学基金国家杰出青年科学基金更多>>
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Application of Saccharomyces boulardii in combination with sulfasalazine in ulcerative colitis patients demonstrates significant effectiveness
《World Journal of Gastrointestinal Surgery》2025年第2期173-182,共10页Chun-Chun Yang Sui Zhang Rui Zhang Ya-Nan Zhao Da-Wei Yang Ming-Yue Yang Li-Jing Huang 
BACKGROUND Ulcerative colitis(UC)is a complex inflammatory bowel disease,and its etiology and pathogenesis remain incompletely elucidated.AIM To analyze the effects of Saccharomyces boulardii in combination with sulfa...
关键词：Saccharomyces boulardii SULFASALAZINE Ulcerative colitis Intestinal microbiota Intestinal barrier function IMPACT 
Ginsenoside Rb1 alleviates colitis in mice via activation of endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 signaling pathway被引量：10
《Acta Pharmacologica Sinica》2021年第9期1461-1471,共11页Jian-yi Dong Kai-jun Xia Wei Liang Lu-lu Liu Fang Yang Xue-sheng Fang Yong-jian Xiong Liang Wang Zi-juan Zhou Chang-yi Li Wei-dong Zhang Jing-yu Wang Da-peng Chen 
National Natural Science Foundation of China(Grant No.81600440);basic research projects of Liaoning Province Universities(Grant No.LQ2017042);Dalian High Level Talent Support program(No.2017RQ017);National Key Research and Development Project of China(2017YFD050160203).
Endoplasmic reticulum(ER)homeostasis is regulated by ER-resident E3 ubiquitin ligase Hrd1,which has been implicated in inflammatory bowel disease(IBD).Ginsenoside Rb1(GRb1)is the major ginsenoside in ginseng with mult...
关键词：inflammatory bowel disease Hrd1 ER stress Fas apoptosis ginsenoside Rb1 SULFASALAZINE DSS TNBS EPITHELIUM 
New approach of medicinal herbs and sulfasalazine mixture on ulcerative colitis induced by dextran sodium sulfate被引量：5
《World Journal of Gastroenterology》2020年第35期5272-5286,共15页Mi-Rae Shin Hae-Jin Park Bu-Il Seo Seong-Soo Roh 
Traditional Korean Medicine R&D Program funded by the Ministry of Health&Welfare through the Korea Health Industry Development Institute(KHIDI),No.HI15C00255;and National Research Foundation of Korea(NRF)funded by the Korean government(MSIP),No.2018R1A5A2025272.
BACKGROUND Sulfasalazine has been used as a standard-of-care in ulcerative colitis for decades,however,it results in severe adverse symptoms,such as hepatotoxicity,blood disorders,male infertility,and hypospermia.Acco...
关键词：Dextran sulfate sodium Ulcerative colitis ANTI-INFLAMMATORY SULFASALAZINE Citrus unshiu peel and Bupleuri radix mixture Apoptosis 
Ferruginol alleviates inflammation in dextran sulfate sodium-induced colitis in mice through inhibiting COX-2, MMP-9 and NF-κB signaling被引量：1
《Asian Pacific Journal of Tropical Biomedicine》2020年第7期308-315,共8页Xiao-Yan Zhu Chun-Ling Zhang Yukiat Lin Min-Yan Dang 
Objective:To assess the anti-inflammatory efficacy of ferruginol on dextran sulfate sodium(DSS)stimulated ulcerative colitis mice.Methods:Ulcerative colitis was induced in C57 BL/6 J mice by administering 2%of DSS thr...
关键词：Ferruginol DEXTRAN SULFATE sodium INFLAMMATION SULFASALAZINE Ucerative COLITIS 
Conventional therapy for moderate to severe inflammatory bowel disease: A systematic literature review被引量：15
《World Journal of Gastroenterology》2019年第9期1142-1157,共16页Adérson Omar Mourao Cintra Damiao Matheus Freitas Cardoso de Azevedo Alexandre de Sousa Carlos Marcela Yumi Wada Taciana Valéria Marcolino Silva Flávio de Castro Feitosa 
funded by Takeda Pharmaceuticals,Brazil
BACKGROUND Despite the advent of biological drugs, conventional therapy continues to be used in moderate to severe inflammatory bowel disease(MS-IBD). This study hypothesized that as a standard of treatment and the pr...
关键词：Inflammatory bowel diseases Steroids SULFASALAZINE MESALAMINE AZATHIOPRINE Methotrexate Mycophenolic acid CYCLOSPORINE TACROLIMUS 6-MERCAPTOPURINE 
Probiotic Medilac-S^(█) for the induction of clinical remission in a Chinese population with ulcerative colitis: A systematic review and meta-analysis被引量：4
《World Journal of Clinical Cases》2018年第15期961-984,共24页Ghania Sohail Xiaoyu Xu Mary C Christman Thomas A Tompkins 
AIM To assess the effects of probiotic Medilac-S~ as adjunctive therapy for the induction of remission of ulcerative colitis(UC) in a Chinese population through a systematic review and meta-analysis. METHODS A syste...
关键词：Clinical remission Systematic review META-ANALYSIS MESALAZINE SULFASALAZINE Ulcerative colitis Medilac-S^(█) 
Expression of fibronectin and MMP-3 and its significance in the patients with ankylosing spondylitis被引量：1
《Asian Pacific Journal of Tropical Medicine》2018年第1期78-81,共4页Jun-Ling Zhu Jian-Yao Zhou Tao Hou Jian-Zhi Zhao Guo-Fang Wang Xiao-Wei Han 
supported by Chinese Medicine Research Program of Zhejiang Province(No.2015ZB121)
Objective: To observe the expression and significance of fibronectin and metalloproteinase-3(MMP-3) in patients with ankylosing spondylitis(AS). Methods: A total of 30 AS patients in our hospital and 30 healthy volunt...
关键词：Ankylosing spondylitis FIBRONECTIN Metalloproteinase-3 SULFASALAZINE 
Geniposide ameliorates TNBS-induced experimental colitis in rats via reducing inflammatory cytokine release and restoring impaired intestinal barrier function被引量：19
《Acta Pharmacologica Sinica》2017年第5期688-698,共11页Bin XU Yan-li LI Ming XU Chang-chun YU Meng-qiao LIAN Ze-yao TANG Chuan-xun LI Yuan LIN 
Geniposide is an iridoid glycosides purified from the fruit of Gardenia jasminoides Ellis, which is known to have antiinflammatory, anti- oxidative and anti-tumor activities. The present study aimed to investigate the...
关键词：GENIPOSIDE SULFASALAZINE intestinal inflammation COLITIS intestinal barrier function AMPK signaling pathway MLCK 
Psoriasis treatment: Unconventional and non-standard modalities in the era of biologics被引量：1
《World Journal of Dermatology》2016年第1期17-51,共35页Vikram K Mahajan 
Psoriasis is a potentially debilitating inflammatory dermatosis affecting 0.2%-4.8% of the population worldwide causing a significant occupational, personal or psychosocial morbidity to these patients for life. The ba...
关键词：Acetretin Azathioprine Balneophototherapy Calcineurin inhibitors CALCIPOTRIOL Calcium dobesilate Climatotherapy Colchicine Cyclosporine DAPSONE Excimer laser Fumarates Grenz ray therapy Hydroxycarbamide Ichthyotherapy ISOTRETINOIN Leflunamide Methotrexate MYCOPHENOLATE mofetil Pentoxifylline Peritoneal dialysis Phototherpy Plaque PSORIASIS Peroxisome proliferator-activated receptors agonists Statins SULFASALAZINE Tonsillectomy 
Is non-biological treatment of rheumatoid arthritis as good as biologics?被引量：3
《World Journal of Orthopedics》2015年第2期278-283,共6页Jyoti Ranjan Parida Durga Prasanna Misra Anupam Wakhlu Vikas Agarwal 
The management of rheumatoid arthritis(RA) in the past three decades has undergone a paradigm shift from symptomatic relief to a "treat-to-target" approach. This has been possible through use of various conventional a...
关键词：Rheumatoid arthritis Disease modifying drugs BIOLOGICS Methotrexate SULFASALAZINE LEFLUNOMIDE CYCLOSPORINE HYDROXYCHLOROQUINE Tumor necrosis factor Remission RADIOLOGIC outcome 
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