RHEUMATOID

作品数:234被引量:565H指数:12
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Hand bone mass in rheumatoid arthritis:A review of the literature被引量:18
《World Journal of Orthopedics》2015年第1期106-116,共11页Gamze Kilic Salih Ozgocmen 
Rheumatoid arthritis(RA) is a common chronic inflammatory disease and periarticular osteoporosis or osteopenia of the inflamed hand joints is an early feature of RA Quantitative measurement of hand bone loss may be an...
关键词:RHEUMATOID ARTHRITIS HAND bone density Dual X-ray ABSORPTIOMETRY PERIARTICULAR Osteoporosis 
Inhibition of rheumatoid arthritis by blocking connective tissue growth factor被引量:4
《World Journal of Orthopedics》2014年第5期653-659,共7页Kazuhisa Nozawa Maki Fujishiro Yoshinari Takasaki Iwao Sekigawa 
Supported by Grant-in-Aid for Scientific Research(C),The Ministry of Education,Culuture,Sports,Science and Technology and The Institute for Environment and Gender-specific Medicine,Juntendo University Graduate School of Medicine
The pathogenesis of rheumatoid arthritis(RA) remains to be completely elucidated so far; however, it is known that proinflammatory cytokines play a pivotal role in the induction of RA. Tumor necrosis factor(TNF-α), i...
关键词:CONNECTIVE tissue growth facto RHEUMATOID ARTHRITIS OSTEOCLASTS Condrocytes Tumor NECROSIS factor-α 
Power Doppler ultrasonographic assessment of the ankle in patients with inflammatory rheumatic diseases被引量:1
《World Journal of Orthopedics》2014年第5期574-584,共11页Takeshi Suzuki 
Ankle involvement is frequent in patients with inflammatory rheumatic diseases, but accurate evaluation by physical examination is often difficult because of the complex anatomical structures of the ankle. Over the la...
关键词:ANKLE Power Doppler Ultrasound RHEUMATOID ARTHRITIS Psoriatic ARTHRITIS SPONDYLOARTHRITIS TENOSYNOVITIS ENTHESITIS 
Thromboembolic disease in patients with rheumatoid arthritis undergoing joint arthroplasty: Update on prophylaxes被引量:4
《World Journal of Orthopedics》2014年第5期645-652,共8页Antonella Mameli Francesco Marongiu 
The risk of venous thromboembolism(VTE) in rheumatoid arthritis(RA) and the higher incidence of RA patients undergoing major orthopedic surgery is well recognized. The objective of the present study is to describe the...
关键词:THROMBOPROPHYLAXIS RHEUMATOID ARTHRITIS ORTHOPAEDIC surgery TOTAL hip ARTHROPLASTY TOTAL knee ARTHROPLASTY 
Rheumatoid arthritis susceptibility genes: An overview被引量:14
《World Journal of Orthopedics》2014年第4期544-549,共6页Izabela Korczowska 
Rheumatoid arthritis(RA) is a chronic, inflammatory autoimmune disease sustained by genetic factors. Various aspects of the genetic contribution to the pathogenetics and outcome of RA are still unknown. Several genes ...
关键词:RHEUMATOID ARTHRITIS Gene Polymorphism Human LEUKOCYTE ANTIGEN GENOME wide association study 
Protein kinase small molecule inhibitors for rheumatoid arthritis: Medicinal chemistry/clinical perspectives被引量:5
《World Journal of Orthopedics》2014年第4期496-503,共8页Charles J Malemud David E Blumenthal 
Supported by A contract from Genentech/Roche Group and the Case Western Reserve University School of Medicine Visual Sciences Research Core,No.P30 EY-011373
Medicinal chemistry strategies have contributed to the development, experimental study of and clinical trials assessment of the first type of protein kinase small molecule inhibitor to target the Janus kinase/Signal T...
关键词:CLINICAL trials Protein KINASE Signal TRANSDUCTION Small molecule inhibitor RHEUMATOID ARTHRITIS 
Efficacy and safety of tofacitinib for treatment of rheumatoid arthritis被引量:1
《World Journal of Orthopedics》2014年第4期504-511,共8页Lisa M Lundquist Sabrina W Cole Martha L Sikes 
Tofacitinib is the first in a new class of nonbiologic disease-modifying antirheumatic drugs(DMARDs), a targeted, synthetic DMARD, approved for the treatment of rheumatoid arthritis(RA) as monotherapy or in combinatio...
关键词:Tofacitinib RHEUMATOID ARTHRITIS JANUS KINASE INHIBITOR 
Arthrodesis of the wrist in rheumatoid arthritis被引量:3
《World Journal of Orthopedics》2014年第4期512-515,共4页Klemens Trieb 
In rheumatoid arthritis the small joints of the feet and hands are the first targets of the autoimmune process. In about one half of the patient the wrist is involved in the first stages of the disease(two years) incr...
关键词:ARTHRITIS RHEUMATOID WRIST Treatment SURGICAL ARTHRODESIS 
Interleukins and interleukin receptors in rheumatoid arthritis: Research, diagnostics and clinical implications被引量:19
《World Journal of Orthopedics》2014年第4期516-536,共21页Lili Magyari Dalma Varszegi Erzsebet Kovesdi Patricia Sarlos Bernadett Farago Andras Javorhazy Katalin Sumegi Zsolt Banfai Bela Melegh 
Supported by The Grant of the Hungarian Science Foundation,No.OTKA K103983
Rheumatoid arthritis(RA) is an autoimmune disease, resulting in a chronic, systemic inflammatory disorder. It may affect many tissues and organs, but it primarily affects the flexible joints. In clinical practice pati...
关键词:RHEUMATOID ARTHRITIS INTERLEUKINS Polymorphisms IMMUNOLOGIC targets Therapy 
Perioperative management of the patient with rheumatoid arthritis被引量:6
《World Journal of Orthopedics》2014年第3期283-291,共9页Megan L Krause Eric L Matteson 
A multidisciplinary approach is required to care for patients with rheumatoid arthritis(RA)in the perioperative period.In preparation for surgery,patients must have a cardiovascular risk assessment performed due to th...
关键词:RHEUMATOID ARTHRITIS PERIOPERATIVE management Disease MODIFYING antirheumatic drugs Tumor NECROSIS factor inhibitors POSTSURGICAL complications 
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