GELATINASES

作品数：12被引量：32H指数：4
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相关领域：医药卫生生物学更多>>
相关作者：刘文虎陈香美傅博更多>>
相关机构：中国人民解放军总医院河北医科大学更多>>
相关期刊：《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Journal of Pharmacy and Pharmacology》《Chinese Medical Journal》更多>>
相关基金：国家自然科学基金北京市自然科学基金更多>>
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ID7 Isolated from Bauhinia variegata Stem Inhibits Tumor Progression and Metastatic Mechanisms of Triple Negative Breast Cancer in Vivo被引量：1
《Journal of Pharmacy and Pharmacology》2019年第7期368-384,共17页Kamilla Monteiro dos Santos Izabela Natalia Faria Gomes Renato JoséSilva Oliveira Fernanda E.Pinto Bruno Oliveira Fabrício P.Batista Rafael Cesar Russo Chagas Hélio B.Santos Ralph G.Thomé Wanderson Romao Rui Manuel Reis Maria Luiza Vilela Oliva Rosy Iara Maciel de Azambuja Ribeiro 
Background:The breast cancer has been the most common form of cancer among women.The triple negative subtype represents 20%of all breast cancer cases in the world and is standing out by affecting young women and being...
关键词：4T1 cells MDA-MB-231 MEDICINAL plants KAEMPFEROL GELATINASES apoptosis cell viabilty in vivo 
Study of Lipocalin-2 Associated with Neutrophilic Gelatinases (uNGAL) in the Urine in Children with the Microbial Inflammatory Diseases of Kidneys and Urinary Tract
《Journal of Biosciences and Medicines》2015年第12期19-25,共7页E. D. Bondarenko A. V. Eremeeva V. V. Dlin A. A. Korsunsky S. B. Orekhova S. Gurbanova 
Purpose of the study: Research of the clinical and diagnostic significance of determination of Lipocalin-2 associated with neutrophilic gelatinases (uNGAL) in the urine of children with urinary tract infection (UTI) a...
关键词：Lipocalin-2 Associated with NEUTROPHILIC GELATINASES (NGAL) Acute PYELONEPHRITIS Urinary Tract Infection CHILDREN 
The effects of interleukin-1β in modulating osteoclast-conditioned medium's influence on gelatinases in chondrocytes through mitogen-activated protein kinases被引量：4
《International Journal of Oral Science》2015年第4期220-231,共12页Jing Xie Na Fu Lin-Yi Cai Tao Gong Guo Li Qiang Peng Xiao-Xiao Cai 
funded by National Natural Science Foundation of China (81201211, 81471803);Funding of State Key Laboratory of Oral Diseases (SKLOD201527);The youth start-up fund (2015SCU11013)
Osteoarthritis is recognised to be an interactive pathological process involving the cartilage, subchondral bone and synovium. The signals from the synovium play an important role in cartilage metabolism, but little i...
关键词：CHONDROCYTE GELATINASES INTERLEUKIN-1Β matrix crosstalk OSTEOARTHRITIS OSTEOCLAST 
In vitro expression of gelatinases in reconstructed melanoma model composited MV3 cells
《Chinese Medical Journal》2013年第16期3196-3197,共2页L(U) Yu ZHANG Wei LU Hong-guang 
To the editor：It has been known that invasion and metastasis of skin melanoma in situ is a complex multi-step process involving in the interaction between melanoma cells and the adjacent stromal cells and basement me...
Effects of Plasmodium falciparum—infected erythrocytes on matrix metalloproteinase-9 regulation in human microvascular endothelial cells
《Asian Pacific Journal of Tropical Medicine》2013年第3期195-199,共5页Sarah D' Alessandro Nicoletta Basilico Mauro Prato 
supported by Universita di Milano(PUR.2009) to Nicoletta Basilico and Charity Funds from Mrs.Franca Squazza to Mauro Prato;Mauro Prato holds a professorshipgranted by Universita Torino and Azienda Sanitaria Locale-19(ASL-19)
Objective:To investigate the regulation of matrix metalloproteinases(MMPs) and tissue inhibitors of melalloproleinases(TIMPs) in human microvascular endothelium(HMEC-1) exposed to erythrocytes infected by different st...
关键词：PLASMODIUM FALCIPARUM MALARIA ENDOTHELIAL cells Matrix METALLOPROTEINASES Tissue inhibitors of METALLOPROTEINASES GELATINASES 
Relationship of gelatinases-tight junction proteins and blood-brain barrier permeability in the early stage of cerebral ischemia and reperfusion被引量：4
《Neural Regeneration Research》2012年第31期2405-2412,共8页Haolin Xin Wenzhao Liang Jing Mang Lina Lin Na Guo Feng Zhang Zhongxin Xu 
Gelatinases matrix metalloproteinase-2 and matrix metalloproteinase-9 have been shown to mediate claudin-5 and occludin degradation, and play an important regulatory role in blood-brain barrier permeability. This stud...
关键词：gelatinases matrix metalloproteinase claudin-5 occludin blood-brain barrier Evans blue middle cerebral artery occlusion reperfusion injury GM6001 junction protein permeability neural regeneration 
High expression of osteoglycin decreases gelatinase activity of murine hepatocarcinoma Hca-F cells被引量：2
《World Journal of Gastroenterology》2009年第48期6117-6122,共6页Xiao-Nan Cui Jian-Wu Tang Bo Song BO Wang Shan-Yan Chen Li Hou 
Supported by National Natural Science Foundation of China,No.30500586
AIM:To investigate the possible correlation between osteoglycin expression and gelatinase activity of mouse hepatocarcinoma Hca-F cells.METHODS:A eukaryotic expression plasmid pIRE Spuro3 osteoglycin(+)was constructed...
关键词：OSTEOGLYCIN TRANSFECTION Hepatocellular carcinoma Neoplasm metastasis Genes GELATINASES 
Osteoglycin Expression Influences Gelatinases Activity of Murine Hepatocarcinoma Cells Cultured with Extract of Lymph Node被引量：1
《Chinese Journal of Cancer Research》2009年第3期171-176,共6页Xiao-nan Cui Jian-wu Tang Li Hou Bo Song Bo Wang 
supported by the National Natural Science Foundation of China (No.30500586)
Objective： To investigate the possible correlation between osteoglycin expression and gelatinases activity of tumor cells. Methods： Eukaryotic expression plasmid and antisense expression plasmid of osteoglycin were...
关键词：OSTEOGLYCIN TRANSFECTION SHRNA Hepatocellular carcinoma Metastasis GELATINASES 
Expression of E-cadherin,beta-catenin,cathepsin D,gelatinases and their inhibitors in invasive ductal breast carcinomas被引量：13
《Chinese Medical Journal》2007年第18期1597-1605,共9页ZHANG Yun-gang DU Juan TIAN Xin-xia ZHONG Yan-feng FANG Wei-gang 
the National Natural Science Foundation of China(No.30670805);Beijing Natural Science Foundation (No. 7063081);the"985"Project Foundation;"211" Project Foundation (TIAN Xin-xia) from Peking University Health Science Center.
Background E-cadhedn, beta-catenin, cathepsin D, matrix metalloproteinase （MMP）-2, MMP-9, tissue inhibitors of metalloproteinase （TIMP）-1 and TIMP-2 are all invasion-related proteins. The expression patterns of th...
关键词：ductal breast carcinomas E-CADHERIN BETA-CATENIN cathepsin D matrix metalloproteinase 2 
Enhanced migration of tissue inhibitor of metalloproteinase overexpressing hepatoma cells is attributed to gelatinases: Relevance to intracellular signaling pathways被引量：7
《World Journal of Gastroenterology》2005年第8期1096-1104,共9页Elke Roeb Anja-Katrin Bosserhoff Sabine Hamacher Bettina Jansen Judith Dahmen Sandra Wagner Siegfried Matern 
Supported by grants from the Federal Ministry of Education Research of Germany, Deutsche Forschungsgemeinschaft (DFG), and Aachen University
AIM: To study the effect of gelatinases (especially MMP-9) on migration of tissue inhibitor of metalloproteinase (TIMP-1) overexpressing hepatoma cells. METHODS: Wild type HepG2 cells, cells stably transfected with TI...
关键词：HepG2 MMP-2 MMP-9 P38MAPK Galardin GENISTEIN 
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