Biophysical cues of the cellular microenvironment significantly influence cell behaviors by mechanotransduction[1,2].For example,the mechanical properties of the extracellular matrix modulate human mesenchymal stem ce...
This work was supported by the National Natural Science Foundation of China(31430029,82130061 and 32171331);the Young Elite Scientist Sponsorship Program byChina Association for Science and Technology(YESS20200077);the Natural Science Foundation of Hubei Province(2021CFB609).
Biophysical cues of the cellular microenvironment tremendously influence cell behavior by mechanotransduction.However,it is still unclear how cells sense and transduce the mechanical signals from 3D geometry to regula...
supported by the MOST 2030 Brain Project (Grant No.2022ZD0208500);the National Natural Science Foundation of China(Grant Nos. 31771149, 81861128001, and 61933003);partly supported by the CAMS Innovation Fund for Medical Sciences (CIFMS)(Grant No.2019-I2M-5-039)。
Sleep deprivation causes disturbances of the neural activity, leading to the impairment of brain functions. However, the exact mechanism of sleep deprivation and how it affects the dynamics of brain activity during th...
This study was supported by National Research Foundation of Korea(NRF)grant funded by the Korean government(MSIT)(No.2020R1A2C2004714);funding from the State Key Laboratory of Solidification Processing in NWPU(No.SKLSP202002).
A one-step method was developed to create a highly biocompatible micropatterned surface on a diamond-like carbon(DLC)through irradiation with a nitrogen ion beam and thus enhance the biocompatibility of osseointegrate...
supported by the National Key R&D Program of China,No.2018YFF0300800;the National Natural Science Foundation of China,Nos.11572043 and 11372043(all to BH).
Focal adhesions are large macromolecular assemblies through which cells are connected with the extracellular matrix so that extracellular signals can be transmitted inside cells.Some studies have focused on the effect...
Surface topography is one of the key factors in regulating interactions between materials and cells.While topographies presented to cells in vivo are non-symmetrical and in complex shapes,current fabrication technique...
Supported by National Natural Science Foundation of China,No.81770621;Ministry of Education,Culture,Sports,Science,and Technology of Japan,KAKENHI,No.16K15604,No.18H02866;Japan Science and Technology Agency-Japan International Cooperation Agency’s(JST-JICA)Science and Technology Research Partnership for Sustainable Development(SATREPS)Project
BACKGROUND To solve the problem of liver transplantation donor insufficiency,an alternative cell transplantation therapy was investigated.We focused on amniotic epithelial cells(AECs)as a cell source because,unlike in...
Cell-substrate interactions play a crucial role in the design of better biomaterials and integration ofimplants with the tissues. Adhesion is the binding process of the cells to the substrate through interactionsbetwe...
Nerve conduits have been a viable alternative to the ‘gold standard’ autograft for treating small peripheral nerve gap injuries. However, they often produce inadequate functional recovery outcomes and are ineffectiv...
Supports from the National Natural Science Foundation of China(11602027);the National Science Foundation for Post-doctoral Scientists of China(2016M600969)
Flower petals have not only diverse macroscopic morphologies but are rich in microscopic surface patterns, which are crucial to their biological functions. Both experimental measurements and theoretical analysis are c...