Objective To investigate the effect of artesunate(ART)on renal and intestinal injury aftercardiopulmonary resuscitation(CPR)in porcine,and to explore its mechanism.Methods A total of 24 healthy male white porcines wer...
support from the Establishment of Sino-Austria“Belt and Road”Joint Laboratory on Traditional Chinese Medicine for Severe Infectious Diseases and Joint Research (2020YFE0205100);the National Key Research and Development Program of China (2020YFA0908000 and 2022YFC2303600);the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine (ZYYCXTD-C-202002);the National Natural Science Foundation of China (82141001,82274182,82074098 and 82173914);the CACMS Innovation Fund (CI2021A05101 and CI2021A05104);the Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences (CI2021B014);the Science and Technology Foundation of Shenzhen (JCYJ20210324115800001);the Fundamental Research Funds for the Central Public Welfare Research Institutes (ZZ14-YQ-050,ZZ14-YQ-051,ZZ14-YQ-052,ZZ14-FL-002,ZZ14-ND-010 and ZZ15-ND-10);the Shenzhen Governmental Sustainable Development Fund (KCXFZ20201221173612034);the Shenzhen Key Laboratory of Kidney Diseases (ZDSYS201504301616234);the Shenzhen Fund for Guangdong Provincial High-level Clinical Key Specialties (SZGSP001).
Liver,as an immune and detoxification organ,represents an important line of defense against bacteria and infection and a vulnerable organ that is easily injured during sepsis.Artesunate(ART)is an anti-malaria agent,th...
This work was supported by Chongqing International Institute for Immunology(2020YJC10);National Natural Science Foundation of China(82071817,82171771,82004171,81971542);Shenzhen Science and Technology Program(YCYJ20210324114602008);Young Elite Scientist Sponsorship Program by CACM(CACM-2020-QNRC2-05);Hong Kong Research Grants Council(17113319,17103821);RGC Theme-based Research Scheme(TRS)(T12-703/19-R);the Centre for Oncology and Immunology under the Health@InnoHK Initiative funded by the Innovation and Technology Commission,The Government of Hong Kong SAR,China.
Dear Editor,Primary Sjogren's syndrome(pSS)is an autoimmune disease characterized by dry eyes and dry mouth caused by glandular inflammation in salivary glands(SG)and lacrimal glands.Currently,pSS patients are sufferi...
Award Number NIH-2R15AT008277-02(USA)from the National Center for Complementary and Integrative Health that provided funding to Pamela Weathers for some of the artemisinin bioavailability studies described and cited herein
Fibrosis is a pathological reparative process that can occur in most organs and is responsible for nearly half of deaths in the developed world.Despite considerable research,few therapies have proven effective and bee...
Supported by the National Natural Science Foundation of China(No.81570104);Key Research and Development Project of Shandong Province(No.2015GSF118025,2015GSF118058,2016GSF201026)。
Although current therapeutic methods against hematological malignancies are effective in the early stage,they usually lose their effectiveness because of the development of drug resistances.Seeking new drugs with sign...
All the original references were provided by the Nobel Laureate Youyou Tu. The publication process involving the discovery of artemisinin was collected and sorted by her first Ph D student, Associate Professor Man-Yua...
Supported by the National Natural Science Foundation of China;No.81070339;the International Science and Technology Cooperation Project of Shanxi;No.2010081068;the Key Laboratory Foundation of Cellular Physiology Department of Shanxi Medical School and Provincial Ministry of Education;No.2010-09;the Fund for Returned Students of Shanxi;No.211-091;the Fund for Returned Medical Doctors of Changzhi Medical College;No.2010-01;Science and Technology Innovation Team Project of Changzhi Medical College;No.CX201409;College Student Innovation and Entrepreneurship Training Project of Shanxi Province;No.2014308;the US NIH(to Cheng Ji);No.R21AA023952 and No.P30DK48522-21
AIM: To evaluate the effect of artesunate(AS) supplementation on bacterial translocation(BT) and gut microbiota in a rat model of liver cirrhosis. METHODS: Fifty-four male Sprague-Dawley rats were randomly divided int...
Front Discovered by Youyou Tu,one of the 2015 Nobel Prize winners in Physiology or Medicine,together with many other Chinese scientists,artemisinin,artemether and artesunate,as well as other artemisinins,have brought ...