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EPITOPES: 作品数：96被引量：141H指数：7; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：郭礼和费俭夏国宏邢力叶欣更多>>; 相关机构：中国科学院上海生命科学研究院郑州大学南昌大学广州血液中心更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金World Health Organization国家重点基础研究发展计划中国博士后科学基金更多>>

Recent advances in the study of epitopes,allergens and immunologic cross-reactivity of edible mango: 《Food Science and Human Wellness》2024年第3期1186-1194,共9页Honglei Guo Yanjun Cong; supported by National Science and Technology Major Project of China (2019YFC1605002);National Natural Science Foundation of China (31872886)。; Mango(Mangifera indica L.)is a tropical fruit that is widely consumed as both fresh fruits and processed products around the world.The high incidence of mango allergy,on the other hand,has sparked widespread concern.T...; 关键词：MANGO ALLERGEN EPITOPE Immunocross-reactivity Prospects

A novel method for identifying SARS-CoV-2 infection mutants via an epitope-specific CD8^(+)T cell test: 《Biosafety and Health》2024年第3期143-152,共10页Congling Qiu Bo Peng Chanchan Xiao Pengfei Chen Lipeng Mao Xiaolu Shi Zhen Zhang Ziquan Lv Qiuying Lv Xiaomin Zhang Jiaxin Li Yanhao Huang Qinghua Hu Guobing Chen Xuan Zou Xiaofeng Liang; the Key Project of Shenzhen Science and Technology Innovation Commission(JCYJ20210324115411030);Natural Science Foundation of China(92169102);R&D Program of Guangzhou Laboratory(SRPG22-006);Sanming Project of Medicine in Shenzhen(SZSM202211023);GuangDong Basic and Applied Basic Research Foundation(2022B1515120043);the Open Project Fund of Guangdong Provincial People’s Hospital(YKY-KF202208);National Natural Science Foundation of China(81902097);Funding by Science and Technology Projects in Guangzhou(SL2023A04J01160);the Guangdong Basic and;Applied Basic Research Foundation(2023A1515140117);the fellowship of China Postdoctoral Science Foundation(2023TQ0136,2023M741379);supported by grants from the National Key Research and Development Plan(2023YFE0118700,2021YFC2301604);the Fundamental Research Funds for the Central Q4 Universities(21623406).; Since the outbreak of the coronavirus disease 2019(COVID-19)epidemic in 2019,the public health system has faced enormous challenges.Tracking the individuals who test positive for severe acute respiratory syndrome coro...; 关键词：Asymptomatic coronavirus disease 2019 (COVID-19) EPITOPES Specific CD8^(+)T cell ELISPOT

Antigen epitopes of animal coronaviruses:a mini-review: 《Animal Diseases》2024年第1期19-26,共8页Mingjun Su Guanghui Zheng Xiangwen Xu Houhui Song; supported by the Natural Science Foundation of Zhejiang Province(Q23C180006);the Zhejiang A&F University Talent Initiative Project(118-203402005901).; Coronaviruses are widespread in nature and can infect mammals and poultry,making them a public health concern.Globally,prevention and control of emerging and re-emerging animal coronaviruses is a great challenge.The m...; 关键词：Animal coronavirus Antigen epitope B-cell epitope T-cell epitope Immune responses Vaccines

ASFV pp62 Protein Has 9 Dominant B-T Cell Combined Epitopes被引量：2: 《Animal Husbandry and Feed Science》2022年第4期13-20,共8页Cao Qianda Dai Bihong Yang Yang Cao Xuelian; [Objective]The paper was to study the basic characteristics of the pp62 protein of the African swine fever virus strain Pig/HLJ/2018,and to provide more basic data for the study of the virus.[Method]We used the ProtPa...; 关键词：African swine fever virus pp62 CP530R Dominant B-T cell combined epitope Phylogenetic tree Visual analysis

Localization Analysis of Heterophilic Antigen Epitopes of H1N1 Influenza Virus Hemagglutinin被引量：1: 《Virologica Sinica》2019年第3期306-314,共9页Chun-Yan Guo Hai-Xiang Zhang Jun-Jun Zhang Li-Jun Sun Hui-Jin Li Dao-Yan Liang Qing Feng Yan Li Yang-Meng Feng Xin Xie Jun Hu; supported by The National Key Research and Development Program of China (Grant No. 2016YFD0500700);The Natural Science Basic Research Program of Shaanxi Province (Grant No. 2016JM8065);Shaanxi Provincial People’s Hospital Incubation Fund Program (Grant No. 2015YX-4); Previous studies have indicated that two monoclonal antibodies(mAbs;A1-10 and H1-84)of the hemagglutinin(HA)antigen on the H1N1 influenza virus cross-react with human brain tissue.It has been proposed that there are h...; 关键词：H1N1 influenza virus HA ANTIGEN MONOCLONAL antibody LOCALIZATION Heterophilic EPITOPE

Chimerically fused antigen rich of overlapped epitopes from latent membrane protein 2 （LMP2） of Epstein-Barr virus as a potential vaccine and diagnostic agent被引量：2: 《Cellular & Molecular Immunology》2016年第4期492-501,共10页Xiaoyun Lin Shao Chen Xiangyang Xue Lijun Lu Shanli Zhu Wenshu Li Xiangmin Chen Xiaozhi Zhong Pengfei Jiang Torsoo Sophia Sename Yi Zheng Lifang Zhang; This work was supported by a grant from the National Natural Science Foundation of China （No： 81372447）.; Epstein-Barr virus （EBV） is prevalent throughout the world and is associated with several malignant diseases in humans. Latent membrane protein 2 （LMP2） of EBV plays a crucial role in the pathogenesis of EBV-assoc...; 关键词：Epstein-Barr virus （EBV） EPITOPE latent membrane protein 2 （LMP2） VACCINE

Computational analysis of antigenic epitopes of avian influenza A (H7N9) viruses被引量：6: 《Science China(Life Sciences)》2015年第7期687-693,共7页LIU Mi SONG TingRui HUA Sha WU AiPing JIANG TaiJiao; supported by the National Basic Research Program of China(2015CB910501);the Major National Earmark Project for Infectious Diseases(2014ZX10004002-001);the Key Research Program of the Chinese Academy of Sciences(KJZD-EW-L09-1-2)to Jiang Tai Jiao;the National Natural Science Foundation of China(31470273)to Wu Ai Ping; Influenza virus can rapidly change its antigenicity, via mutation in the hemagglutinin(HA) protein, to evade host immunity. The emergence of the novel human-infecting avian H7N9 virus in China has caused widespread co...; 关键词：antigenic epitope antigenic evolution HEMAGGLUTININ influenza H7N9 virus

Identification of the Epitopes of Monoclonal Antibodies against P74 of Helicoverpa armigera Nucleopolyhedrovirus: 《Virologica Sinica》2013年第6期360-367,共8页Limin Liao Dianhai Hou Huachao Huang Manli Wang Fei Deng Hualin Wang Zhihong Hu Tao Zhang; supported by the National Science Foundation of China(31130058 to Z.H.).Monoclonal Antibodies against HearNPV P74; P74 is a per os infectivity factor of baculovirus.Here,we report the production of three monoclonal antibodies (mAbs),denoted as 20D9,20F9 and 21E1,raised against P74 of Helicoverpa armigera nucleopolyhedrovirus (Hear...; 关键词：HEARNPV P74 Linear epitope Monoclonal antibody

Advances of Bioinformatics Tools Applied in Virus Epitopes Prediction被引量：7: 《Virologica Sinica》2011年第1期1-7,共7页Simon Rayner; The National Natural Science Foundations of China (30870131);the National Key Projects in the Infectious Fields (2008ZX10002-011, 2008ZX10004-004); In recent years,the in silico epitopes prediction tools have facilitated the progress of vaccines development significantly and many have been applied to predict epitopes in viruses successfully. Herein,a general over...; 关键词：EPITOPE BIOINFORMATICS Epitope prediction algorithms

Natural epitope variants of the hepatitis C virus impair cytotoxic T lymphocyte activity被引量：1: 《World Journal of Gastroenterology》2010年第16期1953-1969,共17页Shuping Wang Rico Buchli Jennifer Schiller Jianen Gao Rodney S VanGundy William H Hildebrand David D Eckels; Supported by The National Institutes of Health, No. NIH-DK-57732; AIM:To understand how interactions between hepatitis C virus(HCV) and the host's immune system might lead to viral persistence or effective elimination of HCV.METHODS:Nucleotides 3519-3935 of the non-structural 3(NS3)...; 关键词：EPITOPES Human T Cells CYTOTOXIC ANERGY VIRAL

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