云南高校图书馆联盟文献共享服务平台- GLIOBLASTOMAS

GLIOBLASTOMAS: 作品数：20被引量：45H指数：5; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：耿道颖文剑波更多>>; 相关机构：复旦大学江苏省人民医院更多>>; 相关期刊：《Genomics, Proteomics & Bioinformatics》《中国神经肿瘤杂志》《Journal of Cancer Therapy》《Chinese Medical Journal》更多>>; 相关基金：国家自然科学基金更多>>

From signalling pathways to targeted therapies: unravelling glioblastoma’s secrets and harnessing two decades of progress被引量：1: 《Signal Transduction and Targeted Therapy》2023年第11期5270-5302,共33页Brittany Dewdney Misty RJenkins Sarah ABest Saskia Freytag Krishneel Prasad Jeff Holst Raelene Endersby Terrance GJohns; S.A.B.is supported by a Victorian Cancer Agency Mid-Career Research Fellowship(MCRF22003);S.F.is supported by a National Health and Medical Research Council of Australia(NHMRC)Ideas Grant(GNT1184421);R.E.has support from a Cancer Council of Western Australia Research Fellowship and a Brainchild Fellowship from the Pirate Ship Foundation;This work was supported in part through M.RJ,S.A.B.,K.P.,R.E.and,S.F.membership of the Brain Cancer Centre;K.P.is supported by an Australian Government Research Training Program Scholarship and the Ann Henderson PhD Scholarship。; Glioblastoma,a rare,and highly lethal form of brain cancer,poses significant challenges in terms of therapeutic resistance,and poor survival rates for both adult and paediatric patients alike.Despite advancements in b...; 关键词：GLIOBLASTOMA THERAPIES TARGETED

HSP90B1-mediated plasma membrane localization of GLUT1 promotes radioresistance of glioblastomas: 《The Journal of Biomedical Research》2023年第5期326-339,共14页Yanhui Li Yuqian Ge Mengjie Zhao Fangshu Ding Xiuxing Wang Zhumei Shi Xin Ge Xiefeng Wang Xu Qian; supported by the National Natural Science Foundation of China(Grant Nos.82072765 to X.Q.and 82172667 to X.W.).; Ionizing radiation is a popular and effective treatment option for glioblastoma(GBM).However,resistance to radiation therapy inevitably occurs during treatment.It is urgent to investigate the mechanisms of radioresist...; 关键词：HSP90B1 GLYCOLYSIS GLUT1 GLIOBLASTOMA radiotherapy

Nanomedicine-based combination therapies for overcoming temozolomide resistance in glioblastomas被引量：2: 《Cancer Biology & Medicine》2023年第5期325-343,共19页Chun Wang Qiushi Li Jian Xiao Yang Liu; supported by the National Key Research and Development Programs of China(Grant No.2018YFA0209700);National Natural Science Foundation of China(Grant No.22077073);Frontiers Science Center for New Organic Matter,Nankai University(Grant No.63181206);the Fundamental Research Funds for the Central Universities,Nankai University(Grant No.63206015)。; Glioblastoma(GBM)is the most common malignant brain tumor.Although current treatment strategies,including surgery,chemotherapy,and radiotherapy,have achieved clinical effects and prolonged the survival of patients,the...; 关键词：Combination therapy drug resistance GLIOBLASTOMA NANOTECHNOLOGY TEMOZOLOMIDE

Resolving the lineage relationship between malignant cells and vascular cells in glioblastomas: 《Protein & Cell》2023年第2期105-122,共18页Fangyu Wang Xuan Liu Shaowen Li Chen Zhao Yumei Sun Kuan Tian Junbao Wang Wei Li Lichao Xu Jing Jing Juan Wang Sylvia MEvans Zhiqiang Li Ying Liu Yan Zhou; supported by grants from the National Natural Science Foundation of China(Nos.31970676,31970770,32270876);the National Key R&D Program of China(No.2018 YFA0800700,2022YFA0806600),and the Fundamental Research Funds for the Central Universities.; Glioblastoma multiforme(GBM),a highly malignant and heterogeneous brain tumor,contains various types of tumor and non-tumor cells.Whether GBM cells can trans-differentiate into non-neural cell types,including mural ce...; 关键词：GLIOBLASTOMA mural cells endothelial cells TRANS-DIFFERENTIATION lineage tracing single-cell sequencing copy number variation

The role of extracellular vesicles in acquisition of resistance to therapy in glioblastomas: 《Cancer Drug Resistance》2021年第1期1-16,共16页Anudeep Yekula Abigail Taylor Alexandra Beecroft Keiko M.Kang Julia L.Small Koushik Muralidharan Zachary Rosh Bob S.Carter Leonora Balaj; Glioblastoma(GBM)is the most aggressive primary brain tumor with a median survival of 15 months despite standard care therapy consisting of maximal surgical debulking,followed by radiation therapy with concurrent and ...; 关键词：GLIOBLASTOMA RESISTANCE extracellular vesicles TEMOZOLOMIDE radiation

Novel approaches to combat chemoresistance against glioblastomas被引量：2: 《Cancer Drug Resistance》2020年第4期686-698,共13页Rheal A.Towner Michelle Zalles Debra Saunders Nataliya Smith; This work was supported by the Oklahoma Medical Research Foundation,and Oblato,Inc.,as reported in published manuscripts.; The poor prognosis of glioblastoma multiforme(GBM)patients is in part due to resistance to current standard-of-care treatments including chemotherapy[predominantly temozolomide(TMZ;Temodar)],radiation therapy and an a...; 关键词：GLIOBLASTOMA pre-clinical models OKlahoma Nitrone 007 transforming growth factor-β1 ELTD1 magnetic resonance imaging

Chimera RNA interference knockdown of γ-synuclein in human cortical astrocytes results in mitotic catastrophe: 《Neural Regeneration Research》2020年第10期1894-1902,共9页Timmy Le Cynthia L.Winham Fotis Andromidas Adam C.Silver Evan R.Jellison Aime A.Levesque Andrew O.Koob; supported by grants from the Connecticut Partnership in Innovation and Education(PIE)Fellowship(to TL);the University of Hartford College of Arts and Sciences Dean’s Fund(to TL,FA,AOK); Elevated levels of γ-synuclein(γ-syn)expression have been noted in the progression of glioblastomas,and also in the cerebrospinal fluid of patients diagnosed with neurodegenerative diseases.γ-Syn can be either inte...; 关键词：apoptosis ASTROCYTE cell cycle GLIOBLASTOMAS phospho-histone H3 proliferation SYNUCLEIN

The association between human cytomegalovirus and glioblastomas: a review被引量：2: 《Neuroimmunology and Neuroinflammation》2017年第6期96-108,共13页Christian BHochhaIter Christopher Carr Brannan EO’NeiII Marcus LWare MichaeI JStrong; Human cytomegalovirus (HCMV) was reported in glioblastoma multiforme (GBM) over a decade ago and this finding has the potential to increase our understanding of the disease and it offers an alternative tumor-specific ...; 关键词：Human CYTOMEGALOVIRUS CYTOMEGALOVIRUS GLIOMAS GLIOBLASTOMA MULTIFORME immunotherapy brain TUMORS next generation sequencing

Differentiation of glioblastomas and solitary metastatic brain tumors using texture analysis of conventional MRI: 《China Medical Abstracts(Internal Medicine)》2016年第2期2-,共1页陈鑫; Objective To investigate the diagnostic value of the texture analysis derived from conventional MR imaging in differentiating glioblastomas from solitary brain metastases.Methods Thirty-four patients with pathological...; 关键词：texture SOLITARY METASTASES metastatic diagnostic DISCRIMINANT enrolled mutual ATTENUATED DISTINGUISH

Evolving Molecular Genetics of Glioblastoma被引量：2: 《Chinese Medical Journal》2016年第4期464-471,共8页Qiu-Ju Li Jin-Quan Cai Cheng-Yin Liu; Objective： To summary the recent advances in molecular research of glioblastoma （GBM） and current trends in personalized therapy of this disease.Data Sources： Data cited in this review were obtained mainly from Pu...; 关键词：Epidermal Growth Factor Receptor GENETICS GLIOBLASTOMAS lsocitrate Dehydrogenase Molecular： PTPRZ1-MET Telomerase Reverse Transcriptase

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