National Natural Science Foundation of China(Grant Nos.22250410258 and 22250410259);the Ministry of Science and Technology of the People's Republic of China for financial support.
The structures assigned to all four members,1-4,of the recently reported favolasin class of natural product have been prepared for the first time by chemical synthesis.Suzuki-Miyaura cross-coupling chemistry was used ...
Generaus financial support was from the National NaturalScience Foundation of China(Nos.21702235,81841001);the Fundamental Research Funds for the Central Public Welfare Research Institutes(Nos.ZZ13-YQ-098,ZZ10-024,ZXKT17053);the Major National Science and Technology Program of China forlnnovative Drug(No.2017ZX09101002-001-001).
of main observation and conclusion Polycylic fused quinazolinones with anti-malarial activity were synthesized through tert-butyl hydro-peroxide(TBHP)-mediated oxidative decarboxylative cyclization between commercaly ...
supported by the Natural Science Foundation of Beijing of China,No.7192235(to LKX)
Artemisinin,also called qinghaosu,is originally derived from the sweet wormwood plant(Artemisia annua),which is used in traditional Chinese medicine.Artemisinin and its derivatives(artemisinins)have been widely used f...
Introduction: Self-medication is a common practice in Benin. It has many consequences on people’s health in general and develops chemoresistance in particular. Aim: The aim of this work is to study the practice of an...
acknowledge to Hodeidah University, Yemen for supporting this work
Objective: To investigate the effect of temperature and pressure on supercritical CO_2 extraction of Triognella foenum graecum Linn seeds, to determine the optimal condition which leads to highest percentage of the ac...
Ministry of Research,Technology,and Higher Education-Indonesia for the financial support of this work through Hibah Penelitian Disertasi Doktor (PDD)T.A 2017
To investigate in vitro antimalarial activity of chalcone derivative compounds against Plasmodium falciparum 3D7 (Pf3D7) strain and in silico antimalarial activity.MethodsSynthesis of the chalcone derivatives was cond...
Malaria has continued to be a health and economic problem in Africa and the world at large. Many anti-malarial drugs have been rendered ineffective due to the emergence of resistant strains of Plamodium falciparum. A ...
The winning of the 2015 Nobel Prize in Physiology or Medicine by William C.Champbell,Satoshi Omura,and the Chinese scientist Youyou Tu marks their pioneering discoveries of novel therapeutic drugs to treat highly deva...
Discovered by Youyou Tu, one of the 2015 Nobel Prize winners in Physiology or Medicine, together with many other Chinese scientists, artemisinin, artemether and artesunate, as well as other artemisinins, have brought ...
Tans-Atovaquone is widely used as an effective drug to treat uncomplicated malaria. But its cis-isomer is not a drug. In the present study, we report energy minimized binding pattern of trans-Atovaquone and its cisiso...