It is hereby declared that the article entitled“miR-34c-3p Inhibits Nasopharyngeal Carcinoma Development via Inhibiting M2 Polarization of Macrophages”(Yuzi Ji,Yujie Wang,Jiqing Ma,Zhihua Yin,Fei Liu,Yanzi Zang,Guan...
supported by the National Natural Science Foundation of China(82273174,82072374);the Key Research and Development Program of Hunan Province(2023DK2001,2023SK2004,2023ZJ1120-2);the China Postdoctoral Science Foundation(2024M763705);Key R&D Program in Xinjiang Uygur Autonomous Region(2022B03019-4).
Circular RNAs(circRNAs)play pivotal roles in the development and progression of various diseases,including malignant tumors.However,the biological functions and the underlying mechanisms of many circRNAs remain elusiv...
supported by the National Natural Science Foundation of China(no.81930072 and no.82172870 to J.Ma);by the Key-Area Research and Development Program of Guangdong Province(no.2019B020230002 to J.Ma).
According to the International Cancer Research Institute of the World Health Organization data,nasopharyngeal carcinoma(NPC)remains a significant health concern,particularly in regions such as Southeast Asia and south...
Supported by The Suzhou Medical Center,No.Szlcyxzx202103;The National Natural Science Foundation of China,No.82171828;The Key R and D Plan of Jiangsu Province(Development of Social),No.BE2021652;The Subject Construction Support Project of The Second Affiliated Hospital of Soochow University,No.XKTJHRC20210011;The Wu Jieping Medical Foundation,No.320.6750.2021-01-12;The Special Project of"Technological Innovation"Project of CNNC Medical Industry Co.Ltd,No.ZHYLTD2021001;The Suzhou Science and Education Health Project,No.KJXW2021018;Foundation of Chinese Society of Clinical Oncology,No.Y-pierrefabre202102-0113 and No.Y-XD202002/zb-0015;The Beijing Bethune Charitable Foundation,No.STLKY0016;The Research Projects of China Baoyuan Investment Co.Ltd,No.270004;The Suzhou Gusu Health Talent Program,No.GSWS2022028;The Open Project of State Key Laboratory of Radiation Medicine and Protection of Soochow University,No.GZN1202302;The New Medical Technology Project of the Second Affiliated Hospital of Soochow University,No.23zl001;The Multi-center Clinical Research Project for Major Diseases in Suzhou,No.DZXYJ202304;The Postgraduate Research and Practice Innovation Program of Jiangsu Province,No.SJCX24_1814;The Gusu Health Talent Research Fund,No.GSWS2022053;The National Natural Science Foundation of China,No.82102824;The Scientific Research Program for Young Talents of China National Nuclear Corporation。
BACKGROUND Bone is a major site of metastasis in nasopharyngeal carcinoma(NPC).Recently,nuclear factor kappa-beta ligand(RANKL)inhibitors have garnered attention for their ability to inhibit osteoclast formation and b...
supported by the Project of Administration of Traditional Chinese Medicine of Guangxi Zhuang Autonomous Region(grant number GZSY22-69);the Middle/Young aged Teachers’Research Ability Improvement Project of Guangxi Higher Education(grant number 2024KY0120).
Objective:To investigate the chemical components of Semen podocarpi extract(SPE)and its effect on nasopharyngeal carcinoma cells and CNE-2R cells.Methods:Chemical components in SPE were identified by UPLC-MS/MS.CCK-8 ...
Objective miR-34c-3p is down-regulated in nasopharyngeal carcinoma(NPC).The biological role of miR-34c-3p in NPC and its underlying mechanisms are unknown and were explored in this study.Methods Flow cytometry and imm...
Guangzhou Science and Technology Planning Project(Project no.20212210006)。
Objective: To investigate the role of Biyan Qingdu Granule combined with micro-radiation in suppressing nasopharyngeal carcinoma and to explore its mechanism of action. Methods: FAT cells of nasopharyngeal carcinoma w...
Lipid metabolic reprogramming is considered one of the most prominent metabolic abnormalities in cancer,and fatty acid metabolism is a key aspect of lipid metabolism.Recent studies have shown that fatty acid metabolis...
Health Commission of Hubei Province Medical Leading Talent Project,and Translational Medicine and Interdisciplinary Research Joint Fund of Zhongnan Hospital of Wuhan University,Grant/Award Numbers:ZNJC201922,ZNJC202007;Key Research&Development Project of Hubei Province,Grant/Award Number:2020BCA069;National Natural Science Foundation of China,Grant/Award Numbers:81803065,81972852;Research Projects of Biomedical Center of Hubei Cancer Hospital,Grant/Award Number:2022SWZX12。
Background:Immunotherapy has revolutionized the therapeutical regimen for nasopharyngeal carcinoma(NPC),yet its response rate remains insufficient.Programmed death-ligand 1(PD-L1)on small extracellular vesicles(sEVs)m...
Objective: Around 50% of new nasopharyngeal carcinoma (NPC) cases come from China. The present study aimed to update the surveillance of NPC survival in southern China, and investigate the survival disparities between...