supported by grants from the Major Projects of Health Science Research Foundation for Middle-Aged and Young Scientist of Fujian Province,China,No.2022ZQNZD01010010;the National Natural Science Foundation of China,No.82371390;Fujian Province Scientific Foundation,No.2023J01725(all to XC).
The neuroinflammatory response mediated by microglial activation plays an important role in the secondary nerve injury of traumatic brain injury.The post-transcriptional modification of N^(6)-methyladenosine is ubiqui...
supported by STI 2030-Major Projects,No.2021ZD0201603(to JL);the Joint Foundation Program of the Chinese Academy of Sciences,No.8091A170201(to JL);the National Natural Science Foundation of China,Nos.T2293730(to XC),T2293731(to XC),T2293734(to XC),62471291(to YW),62121003(to XC),61960206012(to XC),62333020(to XC),and 62171434(to XC);the National Key Research and Development Program of China,Nos.2022YFC2402501(to XC),2022YFB3205602(to XC).
Neuromodulation techniques effectively intervene in cognitive function,holding considerable scientific and practical value in fields such as aerospace,medicine,life sciences,and brain research.These techniques utilize...
Neurodevelopmental processes represent a finely tuned interplay between genetic and environmental factors,shaping the dynamic landscape of the developing brain.A major component of the developing brain that enables th...
supported by the National Natural Science Foundation of China,No.81971031(to ZL);the National Key Research and Development Program of China,No.2022YFE0210100(to JFC);the National Natural Science Foundation of China(Original Exploration Project),No.82151308(to JFC);the National Natural Science Foundation of China(Research Fund for International Senior Scientists),No.82150710558(to JFC);Science&Technology Initiative STI2030-Major Projects,No.2021ZD0203400(to JFC);Key Research and Development Program of Zhejiang Province,No.2023C03079(to JFC);Scientific Research Starting Foundation of Oujiang Laboratory(Zhejiang Laboratory for Regenerative Medicine,Vision and Brain Health),No.OJQDSP2022007(to JFC);Project of State Key Laboratory of Ophthalmology,Optometry and Visual Science,Wenzhou Medical University,No.J01-20190101(to JFC);Scientific Research Starting Foundation of Wenzhou Medical University,No.QTJ12003(to JFC);Department of Science and Technology of Zhejiang Province,No.2023ZY1011(to JFC)。
The excessive buildup of neurotoxicα-synuclein plays a pivotal role in the pathogenesis of Parkinson's disease,highlighting the urgent need for innovative therapeutic strategies to promoteα-synuclein clearance,parti...
supported by awards from the EPSRC Centre for Doctoral Training in Regenerative Medicine(EP/L014904/1,to JW);an NHS bursary(to RHB);an EPSRC Healthcare Technologies award(EP/T013885/1,to DMC)。
Functional recovery in penetrating neurological injury is hampered by a lack of clinical regenerative therapies.Biomaterial therapies show promise as medical materials for neural repair through immunomodulation,struct...
supported by the InnoHK Initiative and the Hong Kong Special Administrative Region Government, China (to SYY)。
Physical exercise is recognized as an effective intervention to improve mood,physical performance,and general well-being.It achieves these benefits through cellular and molecular mechanisms that promote the release of...
supported by the National Natural Science Foundation of China,No.82371444(to YZ);the Natural Science Foundation of Hubei Province,No.2022CFB216(to XC);the Key Research Project of Ministry of Science and Technology of China,No.2022ZD021160(to YZ)。
The hypothalamic-pituitary-adrenal axis regulates the secretion of glucoco rticoids in response to environmental challenges.In the brain,a nuclear receptor transcription fa ctor,the glucocorticoid recepto r,is an impo...
financial support by the self-supporting project of Pazhou Lab(No.PZL2023ZZ0011);by National Key R&D Program of China(No.2019YFA0904801).
Rapid development of artificial intelligence requires the implementation of hardware systems with bioinspired parallel information processing and presentation and energy efficiency.Electrolyte-gated organic transistor...
funded by The Michael J.Fox Foundation for Parkinson’s Research(grant numbers:17244 and 023410);Science Foundation Ireland(grant number:19/FFP/6554)(to ED)。
More than 200 years after Parkinson's disease was first described by the English surgeon whose name would eventually be given to the condition,available treatments remain purely symptomatic,leaving a critical unmet cl...
Neuromodulation for diabetic peripheral neuropathy represents a significant area of interest in the management of chronic pain associated with this condition.Diabetic peripheral neuropathy,a common complication of dia...