NEUROGLOBIN

作品数:20被引量:31H指数:3
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相关领域:医药卫生更多>>
相关作者:龚树生陈广理李穗尹时华陈沛更多>>
相关机构:华中科技大学中南大学吉林大学第二医院吉林大学第一医院更多>>
相关期刊:《Acta Pharmacologica Sinica》《International Journal of Ophthalmology(English edition)》《World Journal of Emergency Medicine》《Neural Regeneration Research》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划吉林省科技厅白求恩医学专项基金上海市教育委员会重点学科基金更多>>
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Neuroglobin Facilitates Neuronal Oxygenation through Tropic Migration under Hypoxia or Anemia in Rat:How Does the Brain Breathe?
《Neuroscience Bulletin》2023年第10期1481-1496,共16页Chun-Yang Li Hai-Feng Jiang Li Li Xiao-Jing Lai Qian-Rong Liu Shang-Bin Yu Cheng-La Yi Xiao-Qian Chen 
This work was supported by the National Natural Science Foundation of China(81972362,82173197,and 81672504).
The discovery of neuroglobin(Ngb),a brain-or neuron-specific member of the hemoglobin family,has revolutionized our understanding of brain oxygen metabolism.Currently,how Ngb plays such a role remains far from clear.H...
关键词:NEUROGLOBIN HYPOXIA Ischemia ANEMIA Neuron ASTROCYTE 
Neuroglobin and neuroprotection:the role of natural and synthetic compounds in neuroglobin pharmacological induction被引量:2
《Neural Regeneration Research》2021年第12期2353-2358,共6页Lidia Ciccone Susanna Nencetti Simone Socci Elisabetta Orlandini 
This work was supported by the Italian Ministero dell’Istruzione,dell’Universitáe della Ricerca PRIN 2017SNRXH3(to EO and SN);PRA_2018_20 University of Pisa(to EO).
Neuroglobin(Ngb)is a 17 kDa monomeric hexa-coordinated heme protein belonging to the globin family.Ngb is mainly expressed in neurons of the central and peripheral nervous system,although moderate levels of Ngb have b...
关键词:NEUROGLOBIN neuroglobin pharmacological induction NEUROPROTECTION neurodegenerative diseases natural compounds synthetic small molecules Alzheimer’s disease Huntington’s disease 
Contribution at the Study of Neuroprotective Properties of Neuroglobin during Severe Chronic Glaucoma
《World Journal of Neuroscience》2020年第1期42-67,共26页Jean Fidèle Nnang Essone Tatiana Harly Mba Aki Angue Mounir Belmalih Rosalie Nkiéma Ludmila Betty Eke Ndouo Emmanuel Anyunzoghe Nathan Ekegue Félix Ovono Abessolo 
Introduction: The mechanisms of overexpression of neuroglobin in patients with severe glaucoma (CG+) remain hypothetical. Objective: To study the anti-apoptotic, anti-hypoxic and anti-oxidant properties of neuroglobin...
关键词:CHRONIC SEVERE GLAUCOMA NEUROGLOBIN Neuroprotective-Properties 
Diagnostic and Prognostic Interests of Plasmatic Neuroglobin during Stroke in Adult at the Acute Phase
《World Journal of Neuroscience》2019年第2期52-70,共19页J. F. Nnang Essone C. Allognon R. Nkiema S. R. Aubin Igombé P. Nzoghe Nguema F. Ovono Abessolo E. Anyunzok E. Ngou Milama 
Introduction: Neuroglobin (Ngb) owes its name to its preferred location in the nervous system. Its plasma concentration increases during cerebral ischemia. However, the interest of its dosage in the diagnosis and the ...
关键词:NEUROGLOBIN STROKE Diagnosis Prognosis 
Neurological adaptations to hypoxia in Tibetan antelope (Pantholops hodgsonii) with a view of molecular biology of respiratory globin-neuroglobin
《中国应用生理学杂志》2012年第6期555-560,共6页Zhen-zhong BAI Ying-zhong YANG Guo-en JIN Lan MA Ri-li Ge 
supported by the"973"National Basic Research Program(2012CB51820500);National Natural Science Foundation of China(NSFC,31160219).
Neuroglobin(Ngb) is a respiratory protein that is preferentially expressed in brain of mouse and man.In this article,Tibetan antelope,living at altitude of 3 000~5 000 m for millions of years,was selected as the mode...
关键词:中枢神经系统 藏羚羊 脑红蛋白 呼吸系统 球蛋白 分子生物学 逆转录聚合酶链反应 缺氧 
Neuroglobin expression in rats after traumatic brain injury被引量:4
《Neural Regeneration Research》2012年第25期1960-1966,共7页Xin Lin Min Li Aijia Shang Yazhuo HU Xiao Yang Ling Ye Suyan Bian ZhongfengWang Dingbiao Zhou 
supported by General Program of National Natural Science Foundation of China,No. 30400465,30571903;Open Project from Medical Neurobiology of State Key Laboratory (09-08) of Fudan University
In this study, we used a rat model of severe closed traumatic brain injury to explore the relationship between neuroglobin, brain injury and neuronal apoptosis. Real-time PCR showed that neuroglobin mRNA expression ra...
关键词:NEUROGLOBIN traumatic brain injury NEURON APOPTOSIS cerebral cortex BAX Bcl-2 neuralregeneration 
Overexpression of the neuroglobin gene delivered by ultrasound-targeted microbubble destruction protects SH-SY5Y cells against cobalt chloride induced hypoxia被引量:3
《Neural Regeneration Research》2011年第25期1947-1953,共7页Qian Yang Dianwen Gao Qingzhu Nie Zhengang Cai Jian Du Lujuan Shan Yuejian Liu 
In this study, we examined the effects of neuroglobin gene (Ngb) transfection into SH-SY5Y cells, using ultrasound-targeted microbubble destruction (UTMD), on cobalt chloride-induced hypoxia. With an ultrasound in...
关键词:ultrasound-targeted microbubble destruction NEUROGLOBIN gene therapy recombinant plasmid SH-SY5Y cells neural regeneration 
Significance of neuroglobin in serum of acute atherosclerotic cerebral infarction patients被引量:4
《Neural Regeneration Research》2011年第27期2140-2145,共6页Shoucai Zhao Zhaohu Chu Lingsong Ma Yinong Chen Lei Wang Benxiao Wang Zili Huang Jun Zhang 
the Science and Technology Plan of Anhui Province, No.08020304111
This study sought to examine neuroglobin (NGB) in the serum of acute cerebral infarction patients with double-antibody sandwich enzyme-linked immunosorbent assay to identify all risk factors, calculate infarct size,...
关键词:neuroglobin acute cerebral infarction onset time morbidity infarct size neurological impairment score 
Expression of neuroglobin in ocular hypertension induced acute hypoxic-ischemic retinal injury in rats被引量:2
《International Journal of Ophthalmology(English edition)》2011年第4期393-395,共3页Shao-Yang Shi Xue-Mei Feng You Li Xun Li and Xiao-Long Chen 
AIM: To investigate the Expression of neuroglobin (Ngb) in the retina of rats with ocular hypertension induced acute retinal hypoxic-ischemic injury. METHODS: Seventy Wistar rats were divided into 7 groups randomly. T...
关键词:NEUROGLOBIN HYPOXIA-ISCHEMIA RETINA 
Effects of Hemin on neuroglobin expression after cardiopulmonary resuscitation in rats被引量:1
《World Journal of Emergency Medicine》2011年第1期54-58,共5页Ai-wen He Ting Yang Shou-quan Chen Zhang-ping Li Hui-ping Li Wei-jia Huang Jun-yan Cheng Jie Zhang Ping Yang Wan-tie Wang 
BACKGROUND: Despite a large amount of resuscitation research, the survival rate after cardiac arrest remains low, and brain injury is the key issue. Neuroglobin (NGB) is an oxygen-binding heme protein found in the...
关键词:Cardiopulmonary resuscitation NEUROGLOBIN Neurodeficit score HEMIN Cerebral injury RATS 
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