POTENTIAL

作品数:3476被引量:6263H指数:27
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相关领域:医药卫生更多>>
相关作者:韦峥姚泽恩王超牛彦徐萍更多>>
相关机构:北京大学复旦大学中国科学院上海交通大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家教育部博士点基金更多>>
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  • 期刊=Chinese Medical Journalx
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Resistance mechanisms and potential therapeutic strategies in relapsed or refractory natural killer/T cell lymphoma
《Chinese Medical Journal》2024年第19期2308-2324,共17页Chengji Wang Liang Wang 
funded by Beijing Physician Scientist Training Project(No.BJPSTP-2024-01)to Liang Wang.
Natural killer/T cell lymphoma(NKTCL)is a malignant tumor originating from NK or T cells,characterized by its highly aggressive and heterogeneous nature.NKTCL is predominantly associated with Epstein-Barr virus infect...
关键词:Natural killer/T cell lymphoma Epstein-Barr virus Chemotherapy resistance ASPARAGINASE IMMUNOTHERAPY 
Role of triggering receptor expressed on myeloid cells-1 in kidney diseases:A biomarker and potential therapeutic target
《Chinese Medical Journal》2024年第14期1663-1673,共11页Yuxi Fan Ye Xu Zhi Huo Hedong Zhang Longkai Peng Xin Jiang Angus W.Thomson Helong Dai 
supported by grants from the National Natural Science Foundation of China(Nos.82070776,82270796,82200849,and 82370761);the Science and Technology Innovation Program of Hunan Province(No.2022RC3071);the Natural Science Foundation of Hunan Province(No.2023JJ40872);the Higher Education Teaching Reform Project of Central South University(No.2023jy110).
Triggering receptor expressed on myeloid cells-1(TREM-1)is a member of the immunoglobulin superfamily.As an amplifier of the inflammatory response,TREM-1 is mainly involved in the production of inflammatory mediators ...
关键词:TREM-1 Kidney diseases Inflammatory response BIOMARKER Therapeutic targets 
Cuproptosis:A potential therapeutic target in clear cell renal cell carcinoma
《Chinese Medical Journal》2024年第11期1378-1380,共3页Yuetong Zhao Jie Li Xiaojie Lu Shuang Wu Yunze Xing Yaxuan Fang Bo Yang 
To the Editor:Copper is a crucial trace element in the body that plays a key role in metabolism and biological functions.Copper ions are found in two forms,Cu^(1+)and Cu^(2+),of which Cu^(1+)is the main form stored in...
关键词:METABOLISM CHEMOTHERAPY POTENTIAL 
Role of ferroptosis in fibrosis:From mechanism to potential therapy
《Chinese Medical Journal》2024年第7期806-817,共12页Xuemeng Qiu Qing Bi Jiyue Wu Zejia Sun Wei Wang 
National Natural Science Foundation of China(No.82070764);Beijing Natural Science Foundation(No.7212040)
Fibrosis,which is a manifestation of the physiological response to injury characterized by excessive accumulation of extracellular matrix components,is a ubiquitous outcome of the repair process.However,in cases of re...
关键词:Ferroptosis FIBROSIS Anti-fibrotic Iron metabolism NECROINFLAMMATION Epithelial-mesenchymal transition 
Potential biomarkers for diagnosis and disease evaluation of idiopathic pulmonary fibrosis被引量:2
《Chinese Medical Journal》2023年第11期1278-1290,共13页Qing Wang Zhaoliang Xie Nansheng Wan Lei Yang Zhixian Jin Fang Jin Zhaoming Huang Min Chen Huiming Wang Jing Feng 
National Natural Science Foundation of China(Nos.81970083 and 82170097)
Idiopathic pulmonary fibrosis(IPF)is a chronic progressive lung disease characterized by progressive lung fibrogenesis and histological features of usual interstitial pneumonia.IPF has a poor prognosis and presents a ...
关键词:Alveolar epithelial cell dysfunction BIOMARKER DIAGNOSIS FIBROGENESIS Extracellular matrix remodeling Idiopathic pulmonary fibrosis Immune dysfunction 
DLG7/DLGAP5 as a potential therapeutic target in gastric cancer
《Chinese Medical Journal》2022年第13期1616-1618,共3页Kang Li Xiangsheng Fu Ping Wu Bianba Zhaxi Hanhuan Luo Qijie Li 
supported by the Key Technology Projects of Tibet Autonomous Region(No.2015XZ01G22);PostDoctor Research Project,West China Hospital,Sichuan University(No.2018HXBH082);China Postdoctoral Science Foundation(No.2019M653413).
To the Editor:Gastric cancer is a highly invasive disease.An estimated 1.09 million cases were diagnosed and 770,000 gastric cancer-related deaths occurred only in 2020.[1]Advanced gastric cancer can no longer be subj...
关键词:THERAPEUTIC GASTRIC CANCER 
Usefulness of the CONUT index upon hospital admission as a potential prognostic indicator of COVID-19 health outcomes被引量:1
《Chinese Medical Journal》2022年第2期187-193,共7页Adrian K.Bengelloun Guillermo J.Ortega Julio Ancochea Ancor Sanz-Garcia Diego A.Rodriguez-Serrano Guillermo Fernandez-Jimenez Rosa Giron Elena Avalos Joan B.Soriano J.Ignacio de Ulibarri 
The work is supported by a grant from the European Union's Horizon 2020 Research and Innovation Programme under Grant Agreement(No 101016216).
Background:In-hospital mortality in patients with coronavirus disease 2019(COVID-19)is high.Simple prognostic indices are needed to identify patients at high-risk of COVID-19 health outcomes.We aimed to determine the ...
关键词:ADMISSION Clinical risk CONUT COVID-19 PROGNOSIS SCORE 
MicroRNAs as potential therapeutic targets for pancreatic cancer被引量:4
《Chinese Medical Journal》2022年第1期4-10,共7页Xiangyu Chu Dan Wei Xinxin Liu Di Long Xiaodong Tian Yinmo Yang 
Pancreatic cancer is one of the most aggressive malignancies. The poor prognosis of pancreatic cancer patients is mainly attributed to low diagnostic rate at the early stage, highly aggressive nature coupled with the ...
关键词:Pancreatic cancer MICRORNA MicroRNA carriers Precision medicine 
Coronavirus disease 2019-associated pulmonary fibrosis:clinical findings,pathogenesis,and potential treatment
《Chinese Medical Journal》2021年第15期1792-1794,共3页Ya-Le Jiang Hua-Ping Dai Chen Wang 
An outbreak of coronavirus disease 2019(COVID-19)has caught global attention and caused enormous damage.2019 novel coronavirus,also known as severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),shares remarkabl...
关键词:ACUTE PATHOGENESIS finding 
Potential therapeutic mechanism of traditional Chinese medicine monomers on neurological recovery after spinal cord injury被引量:1
《Chinese Medical Journal》2021年第14期1681-1683,共3页Tao Zhang Kai Gao Ting-Zhen Yan Cheng-Wei Lyu Chao-Liang Lyu 
the National Natural Science Foundation of China(No.81801906);the Natural Science Foundation of Shandong Province(No.ZR2018PH024);the Jining Science and Technology Key R&D Plan(No.2017SMNS010).
Spinal cord injury(SCI)is a common traumatic disease of the central nervous system;it causes serious physical and psychological harm to patients and a huge economic burden on the entire society.[1]The tough situation ...
关键词:THERAPEUTIC mechanism INJURY 
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