云南高校图书馆联盟文献共享服务平台- PTMS

PTMS: 作品数：19被引量：57H指数：4; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：杨翠莲张宇宏李冰孙源冯健怀更多>>; 相关机构：上海交通大学沃特世科技(上海)有限公司重庆大学广州医学院第三附属医院更多>>; 相关期刊：《Acta Geochimica》《遗传》《Genes & Diseases》《Translational Neurodegeneration》更多>>; 相关基金：国家自然科学基金中央级公益性科研院所基本科研业务费专项中国博士后科学基金美国国家自然科学基金更多>>

Regulations of m^(6)A and other RNA modifications and their roles in cancer: 《Frontiers of Medicine》2024年第4期622-648,共27页Xin-Hui Chen Kun-Xiong Guo Jing Li Shu-Hui Xu Huifang Zhu Guang-Rong Yan; supported by National Natural Science Foundation of China(Nos.82125029,82073106,82341016);Science and Technology Projects in Guangzhou(Nos.2023A03J0390,202201020101,202201020124).; RNA modification is an essential component of the epitranscriptome,regulating RNA metabolism and cellular functions.Several types of RNA modifications have been identified to date;they include N^(6)-methyladenosine(m^...; 关键词：RNA modification WRITERS erasers READERS regulatory subunits PTMS CANCER

Histone post-translational modification and the DNA damage response被引量：3: 《Genes & Diseases》2023年第4期1429-1444,共16页Haoyun Song Rong Shen Xiangwen Liu Xuguang Yang Kun Xie Zhao Guo Degui Wang; supported by National Natural Science Foundation of China(No.82071695,82060535);Natural Science Foundation of Gansu Province,China(No.21JR7RA450)。; DNA is highly vulnerable to spontaneous and environmental timely damage in living cells.DNA damage may cause genetic instability and increase cancer risk if the damages are not repaired timely and efficiently.Human ce...; 关键词：DNA damage DNA damage response HISTONE Post-translational modifications(PTMs)

Microtubule acetylation dyshomeostasis in Parkinson’s disease被引量：1: 《Translational Neurodegeneration》2023年第1期576-600,共25页Padmashri Naren Khan Sabiya Samim Kamatham Pushpa Tryphena Lalitkumar K.Vora Saurabh Srivastava Dharmendra Kumar Khatri Shashi Bala Singh; The inter-neuronal communication occurring in extensively branched neuronal cells is achieved primarily through the microtubule(MT)-mediated axonal transport system.This mechanistically regulated system delivers cargo...; 关键词：Parkinson’s disease Microtubule acetylation TUBULIN PTMS MITOCHONDRIA Axonal transport HDAC6 SIRT2 inhibitors

The micronuclear histone H3 clipping in the unicellular eukaryote Tetrahymena thermophila被引量：1: 《Marine Life Science & Technology》2022年第4期584-594,共11页Fan Wei Bo Pan Jinghan Diao Yuanyuan Wang Yalan Sheng Shan Gao; supported by the National Natural Science Foundation of China(32125006,32070437);China National Postdoctoral Program for Innovative Talents(BX2021277);China Postdoctoral Science Foundation(2021M690144);Natural Science Foundation of Shandong Province of China(ZR2021QC046);Postdoctoral Applied Research Project of Qingdao.; Clipping of the histone H3 N-terminal tail has been implicated in multiple fundamental biological processes for a growing list of eukaryotes.H3 clipping,serving as an irreversible process to permanently remove some po...; 关键词：Histone H3 tail-H3 clipping protease Histone post-translational modifications(PTMs)-Cell development

The emerging role of tubulin posttranslational modifications in cilia and ciliopathies: 《Biophysics Reports》2020年第4期89-104,共16页Kai He Kun Ling Jinghua Hu; the National Institutes of Health(R01DK090038,1R01DK099160);P30 center grant(P30DK90728).; Tubulin posttranslational modifications(PTMs)add*tubulin code*to generate functional diversities of microtubules.Several types of tubulin PTMs accumulate on axonemes and basal bodies of cilia,including acetylation,glu...; 关键词：Tubulin posttranslational modifications(PTMs) CILIA CILIOPATHIES ACETYLATION Glutamylation Glycylation

蛋白质组学及蛋白质翻译后修饰在畜牧领域中的应用研究进展被引量：10: 《中国畜牧兽医》2019年第4期1063-1073,共11页王欣悦张莉; 国家自然基金联合基金重点支持项目"绵羊骨骼肌纤维形成的生物学特征与分子机制研究"(U1503285);中国农业科学院基本科研业务费重大项目储备计划"肉用绵羊基因组学育种技术优化与应用"(Y2017XM02); 蛋白质组学是一门全方位研究生命结构功能、生理功能及生命活动规律的新兴学科,已成为后基因组时代研究的重要内容,在很多领域得到广泛关注,同时为畜牧科学的发展与创新提供了全新的研究思路和技术手段。目前,蛋白质组学在畜禽生长发育...; 关键词：蛋白质组学畜牧蛋白质翻译后修饰(PTMs)

Synthesis of Ras proteins and their application in biofunctional studies被引量：1: 《Chinese Chemical Letters》2018年第7期1043-1050,共8页Jun Hu Pengcheng Zhu Yanmei Li Yongxiang Chen; the National Natural Science Foundation of China (Nos. 21672125, 91753122); Approximately 30% of human cancers are associated with RAS mutation. Ras proteins on the plasma membrane regulate a plenty of important cellular processes. The post-translational modifications(PTMs)of Ras proteins lik...; 关键词：RAS LIPOPEPTIDES SEMI-SYNTHESIS Multi-PTMs Biophysical function

Peptide-based approaches to identify and characterize proteins that recognize histone post-translational modifications: 《Chinese Chemical Letters》2018年第7期1051-1057,共7页Jianwei Lin Xiang David Li; support from the Hong Kong Research Grants Council Collaborative Research Fund(CRF No. C7029-15G);the Areas of Excellence Scheme (No. AoE/P-705/16);the General Research Fund (GRF Nos.17125917 and 17303114);the Early CareerScheme(ECS)(HKU No. 709813P);the National Natural Science Foundation of China(Nos. 21572191 and 91753130); Increasing amount of evidence suggests that post-translational modifications(PTMs) on histones are involved in regulating DNA-associated processes such as gene expression and DNA-damage repair. To identify and charact...; 关键词：Histone PTMs Peptide pull-down Crosslinkers Peptide microarrays Peptide libraries

速来围观，艾默生网络能源PTMS供配电系统前沿解决方案是什么样？: 《UPS应用》2016年第12期80-81,共2页; 当前，随着数据中心技术的发展和对基础设施要求的提高，供配电系统存在的实际问题及面临的现实挑战也日益凸显。对此，艾默生网络能源大中华区PDU产品部总监李晓东，在“思无界·设享非凡-艾默生网络能源2016年华南区设计院专家高端论...; 关键词：艾默生网络能源供配电系统基础设施数据中心 PDU 设计院总监南区

蛋白质修饰组学在肉品质研究中的应用被引量：1: 《遗传》2015年第4期327-335,共9页蒲强罗嘉沈林園李学伟张顺华朱砺; 四川省科技支撑计划项目(编号:2013NZ0041);国家科技支撑计划项目(编号:2013BAD20B07);教育部长江学者和创新团队发展计划(编号:IRT13083)资助; 蛋白质翻译后修饰(Post-translational modifications,PTMs)在生命体中具有十分重要的作用。生命有机体中常见的PTMs有磷酸化、酰化、糖基化、泛素化、乙酰化、氧化和甲基化等。文章主要介绍了蛋白质组学在肉制品科学方面的应用、PTMs...; 关键词：蛋白质组学肌肉翻译后修饰肉质 POST-TRANSLATIONAL modifications (PTMs)

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