RAT_BRAIN

作品数：206被引量：668H指数：13
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相关机构：河北医科大学第二医院北京大学中国药科大学青岛大学医学院附属医院更多>>
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UHPLC-MS/MS Approach for Following Nimodipine Saturation Kinetics in Acute Rat Brain Slice
《Journal of Analysis and Testing》2024年第4期466-477,共12页Zahraa Ali Rita Frank Tímea Körmöczi István Ilisz Ferenc Domoki Roland Weiczner Ferenc Bari Eszter Farkas Róbert Berkecz 
supported by National Research,Development,and Innovation Office-NKFIA through projects:“National Laboratory of Translational Neuroscience(NLTN)Neurodevelopmental disorders”,“Adult nervous system disorders”(RRF-2.3.121-2022-00011);KIM NKFIA 2022-2.1.1-NL-2022-00005.Project No.TKP2021-EGA-32,TKP-2021-EGA-05,and K134334 have been implemented with the support provided by the Ministry of Innovation and Technology of Hungary from the National Research,Development and Innovation Fund,financed under the TKP2021-EGA funding scheme;Further support was provided by the EU’s Horizon 2020 research and innovation program under grant agreement No.739593。
Nimodipine(NMD)has gained increasing attention in the latest scientific studies as it can act alone or in combination with other drugs to relieve or prevent symptoms of traumatic brain injury,ischemic stroke,and migra...
关键词：NIMODIPINE Brain Electrospray ionization(ESI) UHPLC-MS MS ISCHEMIA 
Effects of Curcumin on Neuroinflammation and the Nrf2/HO-1 Pathway in Rat Brains Following Gas Explosion
《Biomedical and Environmental Sciences》2024年第8期943-947,共5页Xinwen Dong Yaguang Su Zheng Luo Lyufei Deng Xiaofeng Han Yifang Liang Sanqiao Yao Weidong Wu Jia Cao Linqiang Tian Yichun Bai Wenjie Ren 
supported by the National Natural Science Foundation of China[U2004102];the Science and Technology Project of Henan Province[232102311071];the Natural Science Foundation of Henan Province[202300410312]。
Gas explosions,a major occupational hazard in China’s coal industry,endanger the lives and health of miners.These explosions cause a specific type of traumatic brain injury with complex mechanisms,leading to disabili...
关键词：damage NRF2 CEREBRAL 
Exercised blood plasma promotes hippocampal neurogenesis in the Alzheimer's disease rat brain被引量：1
《Journal of Sport and Health Science》2024年第2期245-255,共11页Cecilie Skarstad Norevik Aleksi M.Huuha Ragnhild N.RФsbjФrgen Linda Hildegard Bergersen Kamilla Jacobsen Rodrigo Miguel-dos-Santos Liv Ryan Belma Skender Jose Bianco N.Moreira Asgeir Kobro-Flatmoen Menno P.Witter Nathan Scrimgeour Atefe R.Tari 
funded by The Norwegian Research Council,the Liaison Committee between the Central Norway Regional Health Authority;funded by the Coordination for the Improvement of Higher Education PersonnelBrazil(Capes)。
Background:Exercise training promotes brain plasticity and is associated with protection against cognitive impairment and Alzheimer’s disease(AD).These beneficial effects may be partly mediated by blood-borne factors...
关键词：CYTOKINES High-intensity interval training INFLAMMATION NEURONS Plasma transfusion 
Time-Varying Functional Connectivity of Rat Brain during Bipedal Walking on Unexpected Terrain
《Cyborg and Bionic Systems》2023年第1期392-405,共14页Honghao Liu Bo Li Pengcheng Xi Yafei Liu Fenggang Li Yiran Lang Rongyu Tang Nan Ma Jiping He 
supported by the National Key R&D Program of China(Grant Nos.2018YFB1307301 and 2017YFE0117000).
The cerebral cortex plays an important role in human and other animal adaptation to unpredictable terrain changes,but little was known about the functional network among the cortical areas during this process.To addre...
关键词：CONNECTIVITY CONNECTIVITY TERRAIN 
Construction of the rat brain spatial cell firing model on a quadruped robot
《CAAI Transactions on Intelligence Technology》2022年第4期732-743,共12页Naigong Yu Yishen Liao Hejie Yu Ouattara Sie 
National Natural Science Foundation of China,Grant/Award Numbers:61773027,62076014;Natural Science Foundation of Beijing Municipality,Grant/Award Number:4162012。
Physiological studies have shown that rats in a dark environment rely on the limbs and vestibule for their self-motion information,which can maintain the specific firing patterns of grid cells and hippocampal CA3 plac...
关键词：ROBOT NEURAL FIRING 
Pseudotargeted metabolomics for exploring the changes of neurotransmitters profile in aging rat brain and the potential neuroprotective effect of alkaloids from Uncaria rhynchophylla
《Traditional Medicine Research》2022年第5期1-9,共9页Shi-Wei Li Yi-Song Wu Shi-Fei Wu Wen-Long Wei Ming-Yang Qiu Yun Li De-An Guo 
supported by the Shanghai Sailing Program(No.21YF1455800);the National Key R&D Program of China(No.2019YFC1711000);the Qi-Huang Scholar of National Traditional Chinese Medicine Leading Talents Support Program(No.2018);the Chief Scientist of Qi-Huang Project of National Traditional Chinese Medicine Inheritance and Innovation“One Hundred Million”Talent Project(No.2020).
Background:Aging is an essential risk factor for most neurodegenerative diseases,including Alzheimer’s disease and Parkinson’s disease.However,changes in the levels of neurotransmitters that are associated with agin...
关键词：NEUROTRANSMITTERS AGING Uncaria rhynchophylla indole alkaloids neuroprotective effect pseudotargeted metabolomics 
A Map Construction Method Based on the Cognitive Mechanism of Rat Brain Hippocampus
《Computer Modeling in Engineering & Sciences》2022年第5期1147-1169,共23页Naigong Yu Hejie Yu 
This research was funded by the National Science Foundation of China,Grant No.62076014;as well as the Beijing Natural Science Foundation under Grant No.4162012.
The entorhinal-hippocampus structure in the mammalian brain is the core area for realizing spatial cognition.However,the visual perception and loop detection methods in the current biomimetic robot navigation model st...
关键词：Entorhinal-Hippocampus visual SLAM episodic memory spatial cell cognitive map 
Paeoniflorin ameliorates ischemic injury in rat brain via inhibiting cytochrome c/caspase3/HDAC4 pathway被引量：5
《Acta Pharmacologica Sinica》2022年第2期273-284,共12页Yi-fei Liu Lei Zhang Qi Wu Lin-yin Feng 
This study was supported by grants from the National Science&Technology Major Project“Key New Drug Creation and Manufacturing Program”,China(2018ZX09711002-003-013);the Scientific Innovation Project of the Chinese Academy of Sciences(XDA12040304 and XDA12040216);This project was supported by the Shanghai Committee of Science and Technology,China(18DZ2290200).
Paeoniflorin (PF), a bioactive monoterpene glucoside, has shown a variety of pharmacological effects such as anti-inflammation and autophagy modulation etc. In this study, we investigated whether and how PF exerted a ...
关键词：ischemic brain injury PAEONIFLORIN MCAO HDAC4 cytochrome c APOPTOSIS 
Rapid GFAP and Iba1 expression changes in the female rat brain following spinal cord injury被引量：3
《Neural Regeneration Research》2022年第2期378-385,共8页Mawj Mandwie Jordan A.Piper Catherine A.Gorrie Kevin A.Keay Giuseppe Musumeci Ghaith Al-Badri Alessandro Castorina 
The University of Technology Sydney(UTS)Start-up Research Grant 2018 funded this study(to AC)。
Evidence suggests that rapid changes to supporting glia may predispose individuals with spinal cord injury(SCI) to such comorbidities. Here, we interrogated the expression of astrocyte-and microglial-specific markers ...
关键词：affective disorders ASTROCYTES glial fibrillary acidic protein ionized calcium binding adaptor molecule 1 memory MICROGLIA NEUROTRAUMA spinal cord injury 
Bile duct ligation causes opposite impacts on the expression and function of BCRP and P-gp in rat brain partly via affecting membrane expression of ezrin/radixin/moesin proteins被引量：2
《Acta Pharmacologica Sinica》2021年第11期1942-1950,共9页Tong Wu Yun Sheng Yuan-yuan Qin Wei-min Kong Meng-meng Jin Han-yu Yang Xiao-ke Zheng Chang Dai Ming Liu Xiao-dong Liu Li Liu 
supported by the National Natural Science Foundation of China(Nos.81872930,82073922,81673505);the"Double First-Class"University Project(CPU2018GY22).
Breast cancer resistance protein(BCRP)and P-glycoprotein(P-gp)are co-located at blood–brain barrier(BBB)cells,preventing their substrates from entering brain.Accumulating evidence demonstrates that liver failure impa...
关键词：liver failure breast cancer resistance protein P-GLYCOPROTEIN blood-brain barrier ERM proteins 
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