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作品数:1132被引量:4011H指数:26
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相关领域:医药卫生生物学更多>>
相关作者:陈慧王伊林王书奎文岳中刘维屏更多>>
相关机构:浙江大学浙江师范大学中南大学北京师范大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>
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Sleep as a window to understand and regulate Alzheimer's disease:emerging roles of thalamic reticular nucleus
《Neural Regeneration Research》2025年第6期1711-1712,共2页Haoqi Sun Shiqian Shen Robert J.Thomas M.Brandon Westover Can Zhang 
supported by the Massachusetts General Hospital Scientific Projects to Accelerate Research and Collaboration (SPARC) award;Cure Alzheimer’s Fund (to CZ);the National Institutes of Health (NIH),including R01NS102190,RF1NS120947,and R01HL161253 (to MBW),RF1NS120947 (to RJT)。
Introduction:Alzheimer 's disease(AD) is a common neurodegenerative disorder and the primary cause of dementia. Considerable evidence supports the “amyloid hypothesis,” stating that the pathogenesis of AD is primari...
关键词:ALZHEIMER inflammation HYPOTHESIS 
The island rule-like patterns of plant size variation in a young landbridge archipelago:Roles of environmental circumstance and biotic competition
《Plant Diversity》2025年第2期300-310,共11页Zengke Zhang Wensheng Chen Zengyan Li Wentao Ren Ling Mou Junyong Zheng Tian Zhang Hantang Qin Liyi Zhou Bile Sai Hang Ci Yongchuan Yang Shekhar RBiswas Enrong Yan 
supported by the State Key Program of National Natural Science Foundation of China(Grant No.32030068);the“Lump-sum System”Project of Chongqing Talent Plan(Grant No.cstc2022ycjh-bgzxm0204).
The island rule,a general pattern of dwarfism in large species to gigantism in small species on islands relative to mainland,is typically seen as a macroevolutionary phenomenon.However,whether the ecological processes...
关键词:Insular dwarfism and gigantism Island biogeography The environmental stress hypothesis The reduced herbivory hypothesis The relaxed competition hypothesis The resource availability hypothesis 
Research progress on the roles of complement in liver injury
《World Journal of Hepatology》2025年第3期13-24,共12页Li-Li Ou Jin-Lian Jiang Man-Lu Guo Jin-Hua Wu Wei-Wei Zhong Yi-Huai He 
Supported by the Science and Technology Planning Projects of Guizhou Province,No.QKHJC-ZK[2022]YB642;the Science and Technology Planning Projects of Zunyi City,No.ZSKHHZ(2022)344;the WBE Liver Fibrosis Foundation,No.CFHPC2025028;the Chinese Foundation for Hepatitis Prevention and Control Muxin Research Fund of CHB,No.MX202404;Beijing Liver and Gallbladder Mutual Aid Public Welfare Foundation Artificial Liver Special Fund,No.iGandanF-1082024-Rgg018;the Graduate Research Fund Project of Zunyi Medical University,No.ZYK246;the Student Innovation and Entrepreneurship Training Program of Zunyi Medical University,No.2024106610923 and No.S202310661028.
The complement system is crucial for maintaining immunological homeostasis in the liver,playing a significant role in both innate and adaptive immune responses.Dysregulation of this system is closely linked to the pat...
关键词:Complement system Liver injury Immune homeostasis PATHOGENESIS REVIEW 
Update on the roles and applications of extracellular vesicles in depression
《World Journal of Psychiatry》2025年第3期32-48,共17页Jing Wu Jian Lu Ming-Zhi Pan Xiao-Chu Gu Lu Dai Yun Wang Bin Shen Xiao-Bin Zhang 
Supported by Gusu Talent program,No.(2023)105;Suzhou Science and Technology Development Plan Program,No.SKY2023228;Project of Medical Research Fund of Jiangsu Provincial Health Commission,No.Z2023043;Suzhou Clinical Medical Center for Mood Disorders,No.Szlcyxzx202109;Suzhou Clinical Key Disciplines for Geriatric Psychiatry,No.SZXK202116.
Depression is a prevalent mental disorder that affects numerous individuals,manifesting as persistent anhedonia,sadness,and hopelessness.Despite extensive research,the exact causes and optimal treatment approaches for...
关键词:DEPRESSION Extracellular vesicles EXOSOMES Biomarkers Different sources 
Roles of autophagy and long non-coding RNAs in gastric cancer
《World Journal of Gastroenterology》2025年第11期198-206,共9页Thang Viet Luong Mai Thi Thu Cao Nam Van Duc Nguyen Hai Nguyen Ngoc Dang Trung Tran Nguyen 
Gastric cancer(GC)is one of the most aggressive malignancies worldwide and is characterized by its poor prognosis and resistance to conventional therapies.Autophagy and long non-coding RNAs(lncRNAs)play critical yet c...
关键词:AUTOPHAGY Gastrointestinal cancer Gastric cancer Long non-coding RNAs Cancer progression EPIGENETIC 
Comprehensive Analysis of Oncogenic, Prognostic, and Immunological Roles of FANCD2 in Hepatocellular Carcinoma: A Potential Predictor for Survival and Immunotherapy
《Biomedical and Environmental Sciences》2025年第3期313-327,共15页Mengjiao Xu Wen Deng Tingting Jiang Shiyu Wang Ruyu Liu Min Chang Shuling Wu Ge Shen Xiaoxue Chen Yuanjiao Gao Hongxiao Hao Leiping Hu Lu Zhang Yao Lu Wei Yi Yao Xie Minghui Li 
supported by Beijing Science and Technology Commission(grant number Z211100002921059);National Science and Technology Major Projects of China(2017ZX10201201-001-006,2017ZX10201201-002-006,and 2018ZX10715-005-003-005);Digestive Medical Coordinated Development Center of Beijing Hospital Authority(XXZ0302 and XXT28);National Key R&D Program China(2022YFC2603505);Beijing Hospital Authority Clinical Medicine Development with Special Funding Support(XMLX 202127);High-Level Public Health Technical Personnel Training Program of Beijing the Municipal Health Commission(2022-3-050);Capital Health Research and Development of Special(2022-1-2172).
Objective Hepatocellular carcinoma(HCC)is sensitive to ferroptosis,a new form of programmed cell death that occurs in most tumor types.However,the mechanism through which ferroptosis modulates HCC remains unclear.This...
关键词:Hepatocellular carcinoma Ferroptosis Prognostic biomarker IMMUNOTHERAPY 
The role of the MAGE family:molecular expression,oncogenic roles,and prospects for immunotherapy in cancer
《Life Research》2025年第1期16-31,共16页Yu-Ting Niu Ya-Tong Bi Li Zhu 
supported by Startup Fund for Young Faculty at SJTU(SFYF at SJTU)(No.24X010500176).
As a member of the Cancer-Testis Antigens,the Melanoma-associated antigen(MAGE)family is typically expressed in normal tissues such as the testis.However,in various types of tumor cells,their expression is abnormally ...
关键词:Cancer-Testis Antigens MAGE family gene expression tumor biology IMMUNOTHERAPY 
Stakeholder Roles and Relations in Forest Management around the Boumba-Bek National Park, South East Cameroon
《Open Journal of Forestry》2025年第1期1-22,共22页Roseline Gusua Caspa Jean Guy Ndje Mbile Severine Etounou Gwendoline Naah Nyambi Priscilla Ijang Tata Chimene Mfoumou Hirai Masaaki 
This study, which took place around the Boumba-Bek National Park (BBNP) in Cameroon, was based on identifying and characterizing stakeholders in forest resources management, as well as determining the relationships be...
关键词:Stakeholder Participation CONFLICT Collaboration Stakeholder Interaction Sustainable Forest Resources Management 
Emerging roles of extracellular vesicles in oral and maxillofacial areas
《International Journal of Oral Science》2025年第1期32-51,共20页Qianting Wang Jiayu Sun Haci Jiang Mengfei Yu 
supported by grants from the National Natural Science Foundation of China(grant numbers:82001045,82122014,82020108011,82071085)。
The oral and maxillofacial region is a highly complex area composed of multiple tissue types and bears various critical functions of the human body.Diseases in this region pose significant diagnostic and management ch...
关键词:DIAGNOSIS SPECIFICITY EXTRACELLULAR 
Roles of lncRNA in the crosstalk between osteogenesis and angiogenesis in the bone microenvironment
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2025年第2期107-123,共17页Shihua ZHANG Jianmin GUO Yuting HE Zhi’ang SU Yao FENG Lan ZHANG Jun ZOU Xiquan WENG Yu YUAN 
supported by the National Natural Science Foundation of China(No.81901430);the Guangdong Basic and Applied Basic Research Foundation(No.2022A1515010379);the Science and Technology Projects in Guangzhou(No.2023A04J0555);the Guangdong Provincial Key Laboratory of Physical Activity and Health Promotion(No.2021B1212040014),China.
Bone is a highly calcified and vascularized tissue.The vascular system plays a vital role in supporting bone growth and repair,such as the provision of nutrients,growth factors,and metabolic waste transfer.Moreover,th...
关键词:Long noncoding RNA(lncRNA) OSTEOGENESIS Bone angiogenesis OSTEOPOROSIS Bone microenvironment 
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