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TRANSDUCTION: 作品数：235被引量：650H指数：13; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：张罗韩德民卢从明张建华贾文锁更多>>; 相关机构：首都医科大学中国科学院上海生命科学研究院四川大学中国农业大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划北京市科技计划项目更多>>

Effects of estrogen on diverse stem cells and relevant intracellular mechanisms被引量：8: 《Science China(Life Sciences)》2010年第5期542-547,共6页SUN HaiYing1,WANG HaiFeng2 & HU ShiYu1 1School of Pharmacy,Shanghai Jiao Tong University,Shanghai 200240,China 2First Affiliated Hospital,Henan University of Science and Technology,Luoyang 471003,China; Sexual dimorphism definitely exists in the pathogenesis of a variety of cardiovascular,neurodegenerative and bone metabolism disorders.Estrogen affects the healing of ischemic myocardium partially through paracrine gr...; 关键词：ESTROGEN STEM cells SIGNALING TRANSDUCTION

The endocrine regulation network of growth hormone synthesis and secretion in fish: Emphasis on the signal integration in somatotropes被引量：12: 《Science China(Life Sciences)》2010年第4期462-470,共9页LI WenSheng & LIN HaoRan State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and the Guangdong Provincial Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China; supported by the National Basic Research Program of China (Grant No. 2010CB126302);the Earmarked Fund for Modern Agro-industry Technology Research System for Tilapia;the Agriculture Research Special Funds of 3-49;the National High Technology Research and Development Program of China (Grant No. 2007AA091404) to Dr. Li WenSheng; In teleosts, growth hormone (GH) production is governed by multiple neuroendocrine factors from the hypothalamus and other regulators from the pituitary and peripheral organs. Exploring the principles followed by pitu...; 关键词：FISH growth HORMONE RECEPTOR signal TRANSDUCTION

Regulation of mammalian pre-mRNA splicing被引量：7: 《Science China(Life Sciences)》2009年第3期253-260,共8页HUI JingYi State Key Laboratory of Molecular Biology,Institute of Biochemistry and Cell Biology,Shanghai Institutes for Biological Sciences,Chinese Academy of Sciences,Shanghai 200031,China; Supported by the Program of "one Hundred Talented people" of the Chinese Academy of Sciences; In eukaryotes,most protein-coding genes contain introns which are removed by precursor messenger RNA(pre-mRNA) splicing.Alternative splicing is a process by which multiple messenger RNAs(mRNAs) are generated from a si...; 关键词：PRE-MRNA SPLICING ALTERNATIVE SPLICING SPLICING REGULATION signal TRANSDUCTION microRNA

Bioinformatics analyses for signal transduction networks: 《Science China(Life Sciences)》2008年第11期994-1002,共9页LIU Wei1,2, LI Dong2, ZHU YunPing2 & HE FuChu1,2 1 College of Mechanical & Electronic Engineering and Automatization, National University of Defense Technology, Changsha 410073, China 2 State Key Laboratory of Proteomics, Beijing Proteome Research Center, Beijing Institute of Radiation Medicine, Beijing 102206, China; the Chinese Ministry of Science and Technology (Grant Nos. 2006CB910803, 2006CB910706, 2006AA02A312 and 2006AA02Z334);Creative Research Group Science Foundation of China (Grant No. 30621063);Beijing Municipal Science and Technology Project (Grant No. H030230280590); Research in signaling networks contributes to a deeper understanding of organism living activities. With the development of experimental methods in the signal transduction field, more and more mechanisms of signaling ...; 关键词：signal TRANSDUCTION structural MOTIF automated PATHWAYS REGENERATION dynamics simulation

Cloning of artemisinin biosynthetic cDNAs and novel ESTs and quantification of low temperature-induced gene overexpression被引量：1: 《Science China(Life Sciences)》2008年第3期232-244,共13页ZENG QingPing1, ZHAO Chang1, YIN LuLu1, YANG RuiYi1, ZENG XiaoMei1, HUANG Ying2, FENG LiLing3 & YANG XueQin3 1 Laboratory of Biotechnology, Tropical Medicine Institute, Guangzhou University of Chinese Medicine, Guangzhou 510405, China 2 Guangzhou General Hospital, Guangzhou Military Area Command of Chinese PLA, Guangzhou 510010, China 3 Center of Artemisinin Research, Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Supported by the National Natural Science Foundation of China (Grant Nos. 30672614 and 30271591); To isolate and verify novel genes from qinghao (Artemisia annua) based on the development-specific and environment-induced transcriptomics, leaves have been harvested from the flowering A. annua plants and exposed to ...; 关键词：ARTEMISIA annua EXPRESSED sequence tag (EST) ABIOTIC stress signal TRANSDUCTION fluorescent quantification

Expression and function of leptin and its receptor in mouse mammary gland被引量：7: 《Science China(Life Sciences)》2007年第5期669-675,共7页LIN Ye LI QingZhang; Supported by the National Natural Science Foundation of China (Grant No. 30671538); Leptin is an autocrine and paracrine factor which affects the development of duct, formation of gland alveolus, expression of milk protein gene and onset involution of mammary gland. In order to know the function and ...; 关键词：MAMMARY gland leptin OB-Rb expression signal TRANSDUCTION

Characterization of a novel gene, BcMF7,that is expressed preferentially in pollen of Brassica campestris L. ssp. chinensis Makino被引量：1: 《Science China(Life Sciences)》2007年第4期497-504,共8页HUANG Li, CAO JiaShu, ZHANG YuChao & YE YiQun Laboratory of Cell & Molecular Biology, Institute of Vegetable Science, Zhejiang University, Hangzhou 310029, China; Supported by the National Natural Science Foundation of China (Grant No. 30370975);the Key Sci-technology Project of Zhejiang Province, China (Grant No. 2005C12019-02); Pollen formation is important for plant sexual reproduction. To identify the genes that are involved in pollen formation, we performed the genome-wide transcriptional profiling in the flower buds of both male meiotic ...; 关键词：Brassica CAMPESTRIS ssp. chinensis differentially EXPRESSED POLLEN development flower BUDS signal TRANSDUCTION

Hydrogen peroxide homeostasis and signaling in plant cells被引量：21: 《Science China(Life Sciences)》2006年第1期1-11,共11页CHENG Yanli SONG Chunpen; supported by the National Natural Science Foundation of China(Grant Nos.39870372,30370765&30440079);the National Key Basic Special Funds(Grant No.2003CB114305).; The increases of H2O2 concentrations in plant cells often occur under biotic and abiotic stress conditions (e.g. light, environmental stresses and plant hormone abscisic acid). Atmospheric H2O2 as an ancient signal mo...; 关键词：H2O2 signal transduction abscisic acid environmental stresses gene expression apoptosis.

Regulation of apoptotic signal transduction pathways by the heat shock proteins被引量：8: 《Science China(Life Sciences)》2004年第2期107-114,共8页LI Zhengyu1, ZHAO Xia1 & WEI Yuquan2 1. Department of Gynecology and Obstetrics, West China Second Hospital of Sichuan University, Chengdu 610041, China 2. Key Laboratory of Biotherapy of Human Diseases of Ministry of Education, West China Hospital of Sichuan university, Chengdu 610041, China; supported by the National Natural Science Foundation of China(Grant Nos.30070835&30070294);National 863 Project.; The study about apoptotic signal transductions has become a project to reveal the molecular mechanisms of apoptosis. Heat shock proteins (hsps), which play an important role in cell growth and apoptosis, have attracte...; 关键词：heat shock protein APOPTOTIC signal transduction MOLECULAR chaperone caspases.

A new clue for the pathogenesis of hepatitis C virus infection:Activation of the MAPK/ERK signaling initiated by envelope protein 2: 《Science China(Life Sciences)》2003年第5期538-545,共8页赵兰娟刘厚奇朱诗应冯根生戚中田; supported by the National Natural Science Foundation of China(Grant No.30170514);the State 863 High Technology R&D Project of China(No.2002AA214161).; Since cell signal transduction plays an important role in disclosing the nature of human diseases, the pathogenesis of viruses may result from the disturbance of intracellular signal cascades caused by viral proteins....; 关键词：HEPATITIS C virus envelope protein 2 MAPK/ERK signal transduction pathogenesis.

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