CANCER_CELLS

作品数：433被引量：1403H指数：15
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An endogenous neuropeptide hormone assists cancer cells in escaping from immune surveillance
《Science China(Life Sciences)》2023年第6期1451-1453,共3页Chang-Yu Yan Yan-Ping Wu Yi-Fang Li Rong-Rong He 
Unlike tumor chemotherapy,tumor immunotherapy relies heavily on the immune system of the patients.In recent years,immunotherapeutic approaches that target the immune checkpoint(ICT)pathways,have shown promise in cance...
关键词：ENDOGENOUS CANCER CHEMOTHERAPY 
Mechanical transmission enables EMT cancer cells to drive epithelial cancer cell migration to guide tumor spheroid disaggregation被引量：2
《Science China(Life Sciences)》2022年第10期2031-2049,共19页Qing Zhang Feng Lin Jianyong Huang Chunyang Xiong 
supported in part by the National Natural Science Foundation of China (11772006,11972002,11902007);China Postdoctoral Science Foundation (2019M660313)。
Cell phenotype heterogeneity within tumor tissue,especially which due to the emergence of epithelial-mesenchymal transition(EMT) in cancer cells,is associated with cancer invasion and metastasis.However,our understand...
关键词：cancer cell migration traction force E-/N-cadherin mechanics transmission epithelial-mesenchymal transition 
Will cancer cells be defeated by sodium bicarbonate？被引量：2
《Science China(Life Sciences)》2017年第3期326-328,共3页Hongtao Zhang 
supported by the Breast Cancer Research Foundation and the National Institutes of Health to Mark I.Greene (R01CA089481,R01CA149425);the Department of Defense Lung Cancer Research Program Idea Development Award grant to Sunil Singhal (W81XWH-15-1-0362)
Chao et al.reported an improved version of the transarterial chemoembolization（TACE）procedure for large hepatocellular carcinoma（HCC）,in which 5%sodium bicarbonate was infused into tumors to supplement chemotherap...
关键词：碳酸氢钠 癌细胞 随机对照试验 化疗药物 HCC 肝动脉 小规模 
Erratum to:Overdose the addiction A new strategy to ablate cancer cells
《Science China(Life Sciences)》2016年第3期I0001-I0001,共1页Lei Li 
Erratum to： SCIENCE CHINA Life Sciences, November 2015 Vol.58 No.11：1169-1170 doi： 10.1007/s11427-015-4921-5 The figure legend mistakenly referred to Reference 3 instead of Reference 1. It should read： ＂Adapted ...
关键词：勘误 癌细胞 治疗 生命科学 参考文献 DOI 胡锦涛 作者 
Overdose the addiction—A new strategy to ablate cancer cells
《Science China(Life Sciences)》2015年第11期1169-1170,共2页LI Lei 
In the field of antitumor drug development, it is common to see paired images of cultured cancer cells： one mock- treated, and the other subjected to a small molecular drug that leads to cell death or growth suppress...
关键词：癌细胞 小分子药物 药物开发 肿瘤细胞 抗肿瘤 生长抑制 细胞死亡 细胞生存 
A novel manganese complex LMnAc selectively kills cancer cells by induction of ROS-triggered and mitochondrial-mediated cell death被引量：1
《Science China(Life Sciences)》2014年第10期998-1010,共13页LI Xiang ZHAO KaiDi GUO WenJie LIU Xu LIU Jia GAO Jing CHEN QiuYun BAI YiDong 
supported by the National Natural Science Foundation of China(21271090);the Natural Science Foundation of Jiangsu Province(BK2012710);the Society Developing Program of Zhenjiang(SH2008072);the Senior Talent Start-up Fund of Jiangsu University(13JDG064)
We previously identified a novel synthesized metal compound, LMnAc （[L2Mn2（Ac）（H20）e]（Ac） （L=bis（2-pyridylmethyl） amino-2-propionic acid））. This compound exhibited significant inhibition on cancer cell pro...
关键词：Mn（II） complex selective ANTITUMOR autophagy apoptosis MITOCHONDRIA ROS 
Atomic force microscopy imaging and mechanical properties measurement of red blood cells and aggressive cancer cells被引量：16
《Science China(Life Sciences)》2012年第11期968-973,共6页LI Mi LIU LianQing XI Ning WANG YueChao DONG ZaiLi XIAO XiuBin ZHANG WeiJing 
supported by the National Natural Science Foundation of China (Grant Nos. 60904095 and 61175103);CAS FEA International Partnership Program for Creative Research Teams and the State Key Laboratory of Drug Research
Mechanical properties play an important role in regulating cellular activities and are critical for unlocking the mysteries of life. Atomic force microscopy (AFM) enables researchers to measure mechanical properties o...
关键词：atomic force microscopy red blood cell cancer cell mechanical properties Young＇s modulus 
The metabolic switch and its regulation in cancer cells被引量：1
《Science China(Life Sciences)》2010年第8期942-958,共17页ZHOU ShengTao, HUANG CanHua & WEI YuQuan State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China 
supported by the National Basic Research Program of Chi-na (Grant No. 2011CB910703);the National High-Tech Research and Development Program of China (Grant No. 2007AA021205)
The primary features of cancer are maintained via intrinsically modified metabolic activity, which is characterized by enhanced nutrient supply, energy production, and biosynthetic activity to synthesize a variety of ...
关键词：AEROBIC GLYCOLYSIS cancer de novo FATTY acid synthesis GLUTAMINOLYSIS metabolism 
PKCα translocation from mitochondria to nucleus is closely related to induction of apoptosis in gastric cancer cells被引量：4
《Science China(Life Sciences)》2002年第3期237-244,共9页吴乔 叶晓峰 刘苏 苏文金 丁亮 
This work was supported by the National Outstanding Youth Science Foundation of China (Grant No. 39825502) ; National Natural Science Foundation of China (Grant Nos. 39880015 and 30170477).
PKCs have been implicated in the regulation of cellular differentiation, proliferation, apoptosis and signal transduction. It was demonstrated in this study that PKC? was located both at mitochondria and in cytosol in...
关键词：protein KINASE C (PKC)  translocation  apoptosis  mitochondria  gastric cancer cells. 
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