CHOLINE

作品数:133被引量:437H指数:11
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相关领域:医药卫生更多>>
相关作者:李永红黄宗文张鸿彦陈翼洪愉更多>>
相关机构:复旦大学成都军区昆明总医院四川大学华西医院山东大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金江苏省自然科学基金更多>>
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  • 期刊=Neural Regeneration Researchx
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Maternal dietary deficiencies in folic acid or choline worsen stroke outcomes in adult male and female mouse offspring
《Neural Regeneration Research》2023年第11期2443-2448,共6页McCoy Clementson Lauren Hurley Sarah Coonrod Calli Bennett Purvaja Marella Agnes S.Pascual Kasey Pull Brandi Wasek Teodoro Bottiglieri Olga Malysheva Marie A.Caudill Nafisa M.Jadavji 
American Heart Association,No.20AIREA35050015 (to NMJ)。
Maternal one-carbon metabolism plays an important role in early life programming.There is a well-established connection between the fetal environment and the health status of the offspring.Howeve r,there is a knowledg...
关键词:APOPTOSIS choline metabolism folic acid ischemic stroke maternal diet motor function one-carbon metabolism stroke outcome 
Brief electrical nerve stimulation enhances intrinsic repair capacity of the focally demyelinated central nervous system被引量:4
《Neural Regeneration Research》2022年第5期1042-1050,共9页Lydia Ayanwuyi Nataliya Tokarska Nikki A.McLean Jayne M.Johnston Valerie M.K.Verge 
supported by Multiple Sclerosis Society of Canada(MSSOC),No.2362(to VMKV);Canadian Institutes of Health Research(CIHR),No.14238(to VMKV);were supported by University of Saskatchewan College of Medicine Research Awards(Co MGRADs)。
Our lab has shown that brief electrical nerve stimulation(ES)has a dramatic impact on remyelination of lysophosphatidyl choline(LPC)-induced focally demyelinated rat peripheral nerves,while also inducing an axon-prote...
关键词:axon protection DEMYELINATION immune response lysophosphatidyl choline macrophage microglia multiple sclerosis MYELIN nervous system repair neural activity polarization 
Long non-coding RNA GAS5 promotes PC12 cells differentiation into Tuj1-positive neuron-like cells and induces cell cycle arrest被引量:5
《Neural Regeneration Research》2019年第12期2118-2125,共8页He-Yan Zhao Sheng-Tong Zhang Xiang Cheng Hao-Ming Li Lei Zhang Hui He Jian-Bing Qin Wei-Ye Zhang Yan Sun Guo-Hua Jin 
supported by the National Natural Science Foundation of China,No.81501133(to HML);Postgraduate Research&Practice Innovation Program of Jiangsu Province of China,No.KYCX17-1931(to HYZ);Undergraduate Innovation and Entrepreneurship Training Project of Nantong University of China,No.2018150(to STZ);Pre-research Project of Natural Science Foundation of Nantong University of China,No.17ZY19(to HH);Scientific Research Fund Project of Nantong University Xinglin College of China,No.2018K131(to HYZ);Nantong Science and Technology Project of China,No.JC2018064(to HYZ)
Growth arrest-specific 5 (GAS5) is an anti-oncogene that has been extensively studied in tumors. However, research on GAS5 in the context of nervous system disease is rare at present. This study aimed to investigate t...
关键词:nerve REGENERATION growth arrest-specific 5 PC12 CELL neuron proliferation CELL cycle CHOLINE ACETYLTRANSFERASE ACETYLCHOLINE Alzheimer's disease neural REGENERATION 
Modulating neuronal plasticity with choline
《Neural Regeneration Research》2019年第10期1697-1698,共2页Eunice W. M. Chin Eyleen L.K. Goh 
The American psychologist William James once wrote that nervous tissue seems to be endowed with a “very extraordinary” degree of plasticity. To be plastic means to be capable of being molded, receiving shape, or bei...
关键词:The AMERICAN PSYCHOLOGIST TISSUE seems to be endowed COMBINATION of these EVENTS 
The choline pathway as a strategy to promote central nervous system(CNS) remyelination
《Neural Regeneration Research》2015年第9期1369-1370,共2页Thomas Skripuletz Ralf A.Linker Martin Stangel 
Multiple sclerosis is a chronic companied by demyelination inflammatory disease that is ac- and axonal damage resulting in neurological deficits. Remyelination is the natural endogenous repair mechanism of demyelinate...
关键词:CDP REMYELINATION The choline pathway as a strategy to promote central nervous system OPC CNS 
Fusion protein of single-chain variable domain fragments for treatment of myasthenia gravis
《Neural Regeneration Research》2014年第8期851-856,共6页Fangfang Li Fanping Meng Quanxin Jin Changyuan Sun Yingxin Li Honghua Li Songzhu Jin 
supported by the National Natural Science Foundation of China,No.30360100,30760234,30860260,81160373,81360458
Single-chain variable domain fragment (scFv) 637 is an antigen-specific scFv of myasthenia gravis. In this study, scFv and human serum albumin genes were conjugated and the fusion pro-tein was expressed in Pichia pa...
关键词:nerve regeneration myasthenia gravis acetylcholine receptor anti-acetylcholine re-ceptor antibody single-chain variable domain fragment human serum albumin fusion protein immunosuppressive therapy autoimmune disease NSFC grant neural regeneration 
7.0T nuclear magnetic resonance evaluation of the amyloid beta(1–40) animal model of Alzheimer's disease: comparison of cytology verification被引量:6
《Neural Regeneration Research》2014年第4期430-435,共6页Lei Zhang Shuai Dong Guixiang Zhao Yu Ma 
supported by the National Natural Science Foundation of China,No.81141013;a grant for Talents in Beijing,No.2011D003034000019
3.0T magnetic resonance spectroscopic imaging brain function in Alzheimer's disease. However, is a commonly used method in the research ot the role of 7.0T high-field magnetic resonance spectroscopic imaging in brain...
关键词:nerve regeneration Alzheimer's disease AΒ1-40 high-field functional magnetic resonance nuclear magnetic resonance spectroscopy NEUROPATHOLOGY N-ACETYLASPARTATE CREATINE CHOLINE hippocampus NSFC grant neural regeneration 
Special function of nestin^+ neurons in the medial septum-diagonal band of Broca in adult rats被引量:4
《Neural Regeneration Research》2014年第3期308-317,共10页Yuhong Zhao Kaihua Guo Dongpei Li Qunfang Yuan Zhibin Yao 
the Guangdong Natural Science Foundation of China,No.S2011040004372;the Fundamental Research Funds for the Central Universities,No.11ykpy05
Nestin+ neurons have been shown to express choline acetyltransferase (CHAT) in the medial septum-diagonal band of Broca in adult rats. This study explored the projection of nestin+ neu-rons to the olfactory bulb a...
关键词:nerve regeneration nestin choline acetyl transferase NEUROTRANSMITTER medial sep-turn-diagonal band of Broca olfactory bulb olfactory nerve transection the Guangdong NaturalScience Foundation of China neural regeneration 
Eleutheroside B or E enhances learning and memory in experimentally aged rats被引量:8
《Neural Regeneration Research》2013年第12期1103-1112,共10页Debin Huang Zehua Hu Zhaofen Yu 
supported by the Foundation from Department of Education of Hubei Province,No.D20111903
Eleutheroside B or E, the main component of Acanthopanax, can relieve fatigue, enhance memory, and improve human cognition. Numerous studies have confirmed that high doses of acetylcholine significantly attenuate clin...
关键词:neural regeneration traditional Chinese medicine eleutheroside B or E quinolinic acid aged rats Huperzine A learning and memory HIPPOCAMPUS ACETYLCHOLINE CHOLINESTERASE CHOLINE mechanism grants-supported paper NEUROREGENERATION 
Hyperbaric oxygen therapy improves cognitive functioning after brain injury被引量:18
《Neural Regeneration Research》2013年第35期3334-3343,共10页Su Liu Guangyu Shen Shukun Deng Xiubin Wang Qinfeng Wu Aisong Guo 
Hyperbaric oxygen therapy has been widely applied and recognized in the treatment of brain injury; however, the correlation between the protective effect of hyperbaric oxygen therapy and changes of metabolites in the ...
关键词:neural regeneration brain injury hyperbaric oxygen magnetic resonance spectroscopy ASTROCYTES IMMUNOHISTOCHEMISTRY CHOLINE CREATINE N-ACETYLASPARTATE CA3 region Morris water maze hippocampus NEUROREGENERATION 
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