INTERLEUKIN-2

作品数：156被引量：353H指数：9
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相关机构：北京中医药大学中国科学技术大学中国科学院上海生命科学研究院宁夏医科大学更多>>
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In vivo tumorigenicity of glioblastoma transfected with interleukin-2 and/or interleukin-3 gene
《中国实验血液学杂志》1997年第3期297-297,共1页Bo Hong, Wenzhong Wang, Yizhi Yu, Weiping Zhang, Xuetao CaoDepartment of Neurosurgery, Changhai Hospital Department of Immunology, The Second Military Medical University, Shanghai 200433 
The prognosis for patients with primarymalignant glioma remains poor, in spite of a varietyof different forms of treatments. Broad suppressionof humoral and cell-mediated immunity is found inpatients with malignant gl...
关键词：INTERLEUKIN glioma immunity INTERLEUKIN SPITE prognosis cytokine TRANSFECTION SPLENIC longer 
The effects on biological behaviors of P815 murine mastocytoma cell line induced by the transduction of mouse interleukin-2 gene
《中国实验血液学杂志》1997年第3期306-306,共1页Jingqing Yang, Ning Mao, Ning Guo, Weiming Ouyang,Xiaodan Liu, Xiusen LiBeijing Institute of Basic Medical Sciences, Bejing 100850 
The whole coding region including signal peptidesequence of mouse interleukin-2 (mIL-2) cDNA wasobtained by PCR method and then cloned into the propersites of pUC18 vector. Sequencing analysis throughSanger method (di...
关键词：interleukin MURINE CLONED consistency TRANSDUCTION Sequencing infiltration tumorigenesis NONSPECIFIC immunity 
I mmunomodulatory effects of murine melanoma cells transduced with interleukin-2 gene and recombinant interferon-γ
《中国实验血液学杂志》1997年第3期312-313,共2页Wei-Ming Ouyang, Ning Mao, Jian-Min Sun, Chun-Mei Hou, Jing-Qing Yang, De-Lin Du Department of Cell Biology, Beijing Institute of Basic-Medical Sciences, Beijing 100850 
The murine interleukin-2 gene was introduced intomurine melanoma B16 cells by retroviral vector. AfterG418 selection, a clone stably secreting high level ofinterleukin-2 (1038IU per 10~6 cells per 24 hours) wasobtaine...
关键词：melanoma INTERLEUKIN interferon CLONE MURINE PARENTAL INTERLEUKIN stably immunity cytokine 
Lack of correlation between rejection of tumor cells co-expresssing interleukin-2 and B7.1 and vaccine efficiency被引量：1
《中国实验血液学杂志》1997年第3期315-316,共2页G.Richter S.Cayeux C.Becker C.Beck A.Aicher B.Drken T.Blankenstein 
Gene modification of tumor cells to express a varietyof cytokines such as IL-2 or the co-stimulatory moleculeB7. 1 led to increased immunogenicity and reducedtumorigenicity of tumors has several models and thisprocess...
关键词：REJECTION INTERLEUKIN vaccine immunity expressing cytokines immunized comparable NUDE alone 
Human interleukin-2 gene transfer into ovarian cancer cell lines SKOV3, decreased the proliferation, tumorigenesis and enhanced the immunity of the tumor cells
《中国实验血液学杂志》1997年第3期308-308,共1页Zhen-Yu Zhang, Ning Guo, Jing-He Lang, Ning Mao,Pei-Hsien TangBeijing Institute of Basic Medical Sciences, Beijing100850 
To study the effects of human interleukin-2 genetransfer on the morphology, proliferation, tumori-genesis, immunity, and oncogenes expression of tumorcells, the gene encoding human interleukin-2 (IL-2) wasintroduced v...
关键词：interleukin IMMUNITY TUMORIGENESIS encoding clone morphologic PARENTAL collagen vaccine lymphocyte 
The preparation and expression of replication- deficient human interleukin-2 recombinant adenoviruses
《中国实验血液学杂志》1997年第3期334-334,共1页Hirofumi Hamada 
Interleukin-2(IL-2) has been demonstrated to beone of the most effective target genes in cancerimmunogene therapy. There are more than 20 clinicalprotocols of cancer gene therapy introducing IL-2 intotumor patients to...
关键词：REPLICATION INTERLEUKIN melanoma INTERLEUKIN colon DEFICIENT ADENOVIRUS HOMOLOGOUS promoter attractive 
PURGING OF BONE MARROWS CONTAMINATED WITH MYELOID LEUKEMIC CELLS BY INTERLEUKIN-2 AND LYMPHOKINE-ACTIVATED KILLER CELLS被引量：2
《中国实验血液学杂志》1995年第2期204-209,共6页毛宁 
The capability of recombinant human interleukin-2 ( rhIL-2) and lymphokine-activated killer (LAK) cells in the purging of normal human bone marrows contaminated with human myeloid leukemic cell lines was evaluated. Mi...
关键词：INTERLEUKIN-2 lymphokine-activated KILLER CELL PURGING of bone MARROW cells K562 CELL HL-60 CELL 
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