This work was supported by the National Natural Science Foundation of China(82172076,51873142,and 52033006);Jiangsu Key Research and Development Plan(Social Development)Project(BE2020653 and BE2021642);Suzhou Science and Technology Development Project(SYS2019072);Collaborative Innovation Center of Suzhou Nano Science&Technology,the 111 project,Suzhou Key Laboratory of Nanotech-nology and Biomedicine,and Joint International Research Laboratory of Carbon-Based Functional Materials and Devices.
Ischemia-reperfusion (IR) injury represents a major cause of myocardial dysfunction after infarction and thrombolytic therapy, and it is closely related to the free radical explosion and overwhelming inflammatory resp...
BACKGROUND Exposure to high sustained +Gz(head-to-foot inertial load) is known to have harmful effects on pilots' body in flight. Although clinical data have shown that liver dysfunction occurs in pilots, the precise ...
Supported by the National Sciences Foundation of China(Nos.81273968,81471027 and 81401160);Ministerial Project of the National Working Commission on Aging(No.QLB2014W002);Four Hundred Project of Chinese People's Liberation Army(PLA)General Hospital(No.YS201408)
Objective: To investigate the protective effects and potential mechanisms of Shenhua Tablet(肾华片, SHT) on the toll-like receptors(TLRs)-mediated signaling pathways in a rat model of kidney ischemia-reperfusion injur...
the grants from the National Natural Science Foundation of China (No.81300113);the National Undergraduate Innovation and Entrepreneurship Training Program (No.201710472004).
Myocardial damage caused by myocardial ischemia-reperfusion injury (MIRI)is difficult to be alleviated because cardiomyocyte necrosis is an irreversible and unregulated death form.Recently, necroptosis,a necrosis form...
Acute kidney injury(AKI) is a frequent postoperative complication after liver transplantation. The etiology is multifactorial,including perioperative renal status,surgery related events,and postoperative immunosuppres...
Supported by Fondo de Investigaciones Sanitarias,No.FIS PI12/00519;Eirini Pantazi is the recipient of a fellowship from AGAUR,No.2012FI_B00382,Generalitat de Catalunya,Barcelona,Catalonia,Spain
AIM:To investigate the possible involvement of Sirtuin1(SIRT1)in rat orthotopic liver transplantation(OLT),when Institute Georges Lopez 1(IGL-1)preservation solution is enriched with trimetazidine(TMZ).METHODS:Male Sp...
supported by a grant from the Health Department Foundation of Zhejiang Province(2010KYA102)
Objective:To investigate the protective function of tocilizumab in human cardiac myocytes ischemia-reperfusion injury.Methods:The human cardiac myocytes were treated by tocilizumab with different concentrations(1.0 mg...
supported by Liaoning Provincial,Science and Technology Department Project of Liaoning Province(No 2011225015)
Objective:To investigate the effect of salvianolic acid B on rats with myocardial ischemiareperfusion injury.Methods:SD rats were randomly divided into five groups(n=10 in each group):A sham operation group,B ischemic...
The present study was undertaken to examine the effects of methylprednisolone on the expression and activity of calpain in spinal cord tissue following spinal cord ischemia-reperfusion injury in rats. Adult male Sprag...