ISCHEMIA-REPERFUSION

作品数:210被引量:1347H指数:17
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相关领域:医药卫生更多>>
相关作者:张均田陈永红杜冠华张玲妹孙凤艳更多>>
相关机构:中国医学科学院北京协和医学院上海医科大学中国药科大学中国科学院上海生命科学研究院更多>>
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相关基金:国家自然科学基金中国博士后科学基金湖北省自然科学基金国家教育部博士点基金更多>>
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Macrophage-targeting gene silencing orchestrates myocardial microenvironment remodeling toward the anti-inflammatory treatment of ischemia-reperfusion (IR) injury被引量:3
《Bioactive Materials》2022年第11期320-333,共14页Yao Wang Mengying Hou Shanzhou Duan Ziyin Zhao Xuejie Wu Yongbing Chen Lichen Yin 
This work was supported by the National Natural Science Foundation of China(82172076,51873142,and 52033006);Jiangsu Key Research and Development Plan(Social Development)Project(BE2020653 and BE2021642);Suzhou Science and Technology Development Project(SYS2019072);Collaborative Innovation Center of Suzhou Nano Science&Technology,the 111 project,Suzhou Key Laboratory of Nanotech-nology and Biomedicine,and Joint International Research Laboratory of Carbon-Based Functional Materials and Devices.
Ischemia-reperfusion (IR) injury represents a major cause of myocardial dysfunction after infarction and thrombolytic therapy, and it is closely related to the free radical explosion and overwhelming inflammatory resp...
关键词:Myocardial ischemia-reperfusion(IR)injury Reduction-responsive branched poly(β-amino ester) siRNA/miRNA delivery ANTI-INFLAMMATION Microenvironment remodeling 
Effects of positive acceleration(+Gz stress) on liver enzymes,energy metabolism,and liver histology in rats被引量:1
《World Journal of Gastroenterology》2019年第3期346-355,共10页Bin Shi Xian-Qiang Wang Wei-Dong Duan Guo-Dong Tan Han-Jing Gao Ying-Wei Pan Qing-Jun Guo Hong-Yi Zhang 
BACKGROUND Exposure to high sustained +Gz(head-to-foot inertial load) is known to have harmful effects on pilots' body in flight. Although clinical data have shown that liver dysfunction occurs in pilots, the precise ...
关键词:Positive acceleration +GZ LIVER function ANIMAL models LIVER METABOLISM ISCHEMIA-REPERFUSION INJURY 
Protective Effects and Mechanisms of Shenhua Tablet(肾华片)on Toll-Like Receptors in Rat Model of Renal Ischemia-Reperfusion Injury被引量:6
《Chinese Journal of Integrative Medicine》2019年第1期37-44,共8页LI Qing-ping WEI Ri-bao YANG Xi ZHENG Xiao-yong SU Ting-yu HUANG Meng-jie YIN Zhong CHEN Xiang-mei 
Supported by the National Sciences Foundation of China(Nos.81273968,81471027 and 81401160);Ministerial Project of the National Working Commission on Aging(No.QLB2014W002);Four Hundred Project of Chinese People's Liberation Army(PLA)General Hospital(No.YS201408)
Objective: To investigate the protective effects and potential mechanisms of Shenhua Tablet(肾华片, SHT) on the toll-like receptors(TLRs)-mediated signaling pathways in a rat model of kidney ischemia-reperfusion injur...
关键词:SHENHUA TABLET Chinese medicine kidney INJURY TOLL-LIKE receptors MYELOID differentiation factor 88 ISCHEMIA-REPERFUSION INJURY 
The role of RIP3 in cardiomyocyte necrosis induced by mitochondrial damage of myocardial ischemia-reperfusion被引量:12
《Acta Biochimica et Biophysica Sinica》2018年第11期1131-1140,共10页Huifang Hou Yongling Wang Qiong Li Zaibing Li Yan Teng Jingyu Li Xiaoying Wang Junli Chen Ning Huang 
the grants from the National Natural Science Foundation of China (No.81300113);the National Undergraduate Innovation and Entrepreneurship Training Program (No.201710472004).
Myocardial damage caused by myocardial ischemia-reperfusion injury (MIRI)is difficult to be alleviated because cardiomyocyte necrosis is an irreversible and unregulated death form.Recently, necroptosis,a necrosis form...
关键词:RIP3 Drp1 CARDIOMYOCYTE NECROSIS MYOCARDIAL ISCHEMIA-REPERFUSION INJURY MITOCHONDRIAL damage 
Protecting kidneys in liver transplant patients:A pathway to preventive interventions被引量:2
《World Journal of Hepatology》2018年第9期637-638,共2页Lena Sibulesky Scott W Biggins Raimund Pichler 
Acute kidney injury(AKI) is a frequent postoperative complication after liver transplantation. The etiology is multifactorial,including perioperative renal status,surgery related events,and postoperative immunosuppres...
关键词:Acute KIDNEY INJURY Liver transplantation Hepatic ISCHEMIA-REPERFUSION INJURY MARGINAL GRAFTS Small interfering ribonucleic acid 
Sirtuin 1 in rat orthotopic liver transplantation:An I GL-1 preservation solution approach被引量:5
《World Journal of Gastroenterology》2015年第6期1765-1774,共10页Eirini Pantazi Mohamed Amine Zaouali Mohamed Bejaoui Emma Folch-Puy Hassen Ben Abdennebi Ana Teresa Varela Anabela Pinto Rolo Carlos Marques Palmeira Joan Roselló-Catafau 
Supported by Fondo de Investigaciones Sanitarias,No.FIS PI12/00519;Eirini Pantazi is the recipient of a fellowship from AGAUR,No.2012FI_B00382,Generalitat de Catalunya,Barcelona,Catalonia,Spain
AIM:To investigate the possible involvement of Sirtuin1(SIRT1)in rat orthotopic liver transplantation(OLT),when Institute Georges Lopez 1(IGL-1)preservation solution is enriched with trimetazidine(TMZ).METHODS:Male Sp...
关键词:SIRTUIN 1 ISCHEMIA-REPERFUSION INJURY LIVER transp 
Nitrite,a novel method to decrease ischemia/reperfusion injury in the rat liver被引量:8
《World Journal of Gastroenterology》2015年第6期1775-1783,共9页Bergthor Bjrnsson Linda Bojmar Hans Olsson Tommy Sundqvist Per Sandstrm 
AIM:To investigate whether nitrite administered prior to ischemia/reperfusion(I/R)reduces liver injury.METHODS:Thirty-six male Sprague-Dawley rats were randomized to 3 groups,including sham operated(n=8),45-min segmen...
关键词:ISCHEMIA-REPERFUSION INJURY NITRITE Liver ISCHEMIA 
Protective function of tocilizumab in human cardiac myocytes ischemia reperfusion injury被引量:6
《Asian Pacific Journal of Tropical Medicine》2015年第1期48-52,共5页Hai-Feng Cheng Yan Feng Da-Ming Jiang Kai-Yu Tao Min-Jian Kong 
supported by a grant from the Health Department Foundation of Zhejiang Province(2010KYA102)
Objective:To investigate the protective function of tocilizumab in human cardiac myocytes ischemia-reperfusion injury.Methods:The human cardiac myocytes were treated by tocilizumab with different concentrations(1.0 mg...
关键词:TOCILIZUMAB HUMAN CARDIAC MYOCYTES ISCHEMIA-REPERFUSION INJURY Protection 
Effect and mechanism of salvianolic acid B on the myocardial ischemiareperfusion injury in rats被引量:24
《Asian Pacific Journal of Tropical Medicine》2014年第4期280-284,共5页Ling Xue Zhen Wu Xiao-Ping Ji Xia-Qing Gao Yan-Hua Guo 
supported by Liaoning Provincial,Science and Technology Department Project of Liaoning Province(No 2011225015)
Objective:To investigate the effect of salvianolic acid B on rats with myocardial ischemiareperfusion injury.Methods:SD rats were randomly divided into five groups(n=10 in each group):A sham operation group,B ischemic...
关键词:ISCHEMIA-REPERFUSION INJURY MYOCARDIAL INFARCTION Salvianolic ACID B INFLAMMATORY response 
Effects of Methylprednisolone on the Expression and Activity of Calpain Following Ischemia-Reperfusion Spinal Cord Injury in Rats
《Neuroscience & Medicine》2014年第1期23-31,共9页Zifeng Zhang Jinquan Xu Yushu Bai Tiesheng Hou 
The present study was undertaken to examine the effects of methylprednisolone on the expression and activity of calpain in spinal cord tissue following spinal cord ischemia-reperfusion injury in rats. Adult male Sprag...
关键词:METHYLPREDNISOLONE Spinal CORD INJURY ISCHEMIA-REPERFUSION INJURY CALPAIN 
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