supported by grants from the Swiss National Science Foundation(310030-182332 and 310030L-208141)(to JP)。
The challenge of protecting the brain resides in the unique characteristics of neurons,as they are postmitotic,long-lived,excitable,and polarized cells with long and fragile axons and dendrites.The complexity of the m...
supported by MICIU(grant number PID2021-128133NB-100/AEI/FEDER10.13039/501100011033 to JMHG);by the National Institutes of Health(grant number R01 NS083858 to SAK);the Intramural Grants Program IGPP00057(to SAK);VIC enjoys a FPU contract from the Comunidad de Madrid(PIPF-2022/SAL-GL-25948)。
The involvement of the excitatory amino acids glutamate and aspartate in ce rebral ischemia and excitotoxicity is well-documented.Nevertheless,the role of non-excitatory amino acids in brain damage following a stroke ...
supported partly by the National Natural Science Foundation of China,No.82071332;the Chongqing Natural Science Foundation Joint Fund for Innovation and Development,No.CSTB2023NSCQ-LZX0041 (both to ZG)。
Some studies have confirmed the neuroprotective effect of remote ischemic conditioning against stroke. Although numerous animal researches have shown that the neuroprotective effect of remote ischemic conditioning may...
supported by the JSPS KAKENHI Grant-in-Aid for Scientific Research(Grant number:21K19441,22H03183)(to MK);Early-Career Scientists(Grant number:21K15185)(to IN)and(Grant number:20K16485)(to MH).
Stroke is the second leading cause of death and the third leading cause of disability worldwide after heart disease.Researchers predict that stroke deaths and permanent disabilities will increase worldwide by the year...
supported by the United States Department of Veterans Affairs Rehabilitation Research and Development Service (RR&D)[Merit Review Award numbers B3123-I/101 RX003123 and B3986-R/I01 RX003986-01A1]。
Traumatic brain inju ry-induced unfavorable outcomes in human patients have independently been associated with dysregulated levels of monoamines,especially epinephrine,although few preclinical studies have examined th...
funding support from the National Health and Medical Research Council (NHMRC;application id:2003351) of Australia (to BAS)。
Ischemic stro ke occurs when a blood vessel in the brain is occluded.In the immediate aftermath.blood flow becomes deficient in regions supplied by the blocked vessel.This leads to the development of a core region,whe...
National Institute of Health (R01-HL143750);American Heart Association (19TPA34890022) to LY。
Ischemic stroke represents a heavy burden on public health.Currently,recanalization is the only effective therapy for ischemic stroke in a small population of eligible patients.However,there is no effective adjunct me...
supported by the National Natural Science Foundation of China,No.82271747(to ZLL);Medical and Health Science and Technology Program of Zhejiang Province of China,No.2023RC048(to WL)。
Hypoxic-ischemic encephalopathy,which predisposes to neonatal death and neurological sequelae,has a high morbidity,but there is still a lack of effective prevention and treatment in clinical practice.To better underst...
supported by the American Heart Association (856061) to JFMM;by the NINDS (R01 5R01NS108779 and 5R01NS094543) to LDM
Stroke is the second leading cause of death and a major cause of disability worldwide,and biological sex is an important determining factor in stroke incidence and pathology.From childhood through adulthood,men have a...
supported by the National Natural Science Foundation of China,Nos.81600738(to FF),81771239(to ZF),81801300(to NS)。
Ischemic and traumatic insults to the central nervous system account for most serious acute and fatal brain injuries and are usually characterized by primary and secondary damage.Secondary damage presents the greatest...