ISCHEMIC_STROKE

作品数:655被引量:2857H指数:25
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相关作者:张祥建陈林玉祝春华乔会敏虞珊珊更多>>
相关机构:河北医科大学第二医院中南大学上海市东方医院四川大学华西医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Activation of endogenous neurogenesis and angiogenesis by basic fibroblast growth factor-chitosan gel in an adult rat model of ischemic stroke被引量:6
《Neural Regeneration Research》2024年第2期409-415,共7页Hongmei Duan Shulun Li Peng Hao Fei Hao Wen Zhao Yudan Gao Hui Qiao Yiming Gu Yang Lv Xinjie Bao Kin Chiu Kwok-Fai So Zhaoyang Yang Xiaoguang Li 
supported by the National Natural Science Foundation of China,Nos.81941011(to XL),31771053(to HD),31730030(to XL),31971279(to ZY),31900749(to PH),31650001(to XL),31320103903(to XL),31670988(to ZY);the Natural Science Foundation of Beijing,Nos.7222004(to HD);a grant from Ministry of Science and Technology of China,Nos.2017YFC1104002(to ZY),2017YFC1104001(to XL);a grant from Beihang University,No.JKF-YG-22-B001(to FH)。
Attempts have been made to use cell transplantation and biomaterials to promote cell proliferation,differentiation,migration,and survival,as well as angiogenesis,in the context of brain injury.However,whether bioactiv...
关键词:adult endogenous neurogenesis ANGIOGENESIS basic fibroblast growth factor-chitosan gel CHITOSAN functional recovery ischemic stroke neural stem cell newborn neuron 
Effects of primary microglia and astrocytes on neural stem cells in in vitro and in vivo models of ischemic stroke被引量:8
《Neural Regeneration Research》2021年第9期1677-1685,共9页Sheng-Jun Wen Xi-Min Zheng Li-Fen Liu Na-Na Li Hai-An Mao Liang Huang Qiong-Lan Yuan 
supported by the National Natural Science Foundation of China,Nos.81371213,81070987,30971531;grants from the Ministry of Science and Technology of China,Nos.2010CB945600,2010CB945601(all to QLY)。
Transplantation of neural stem cells(NSCs) can protect neurons in animal stroke models;however, their low rates of survival and neuronal differentiation limit their clinical application. Glial niches, an important loc...
关键词:ASTROCYTES GLUTAMATE MICROGLIA neural stem cells NEUROGENESIS neurons PEROXIDE repair stroke 
Injectable silk sericin scaffolds with programmable shape-memory property and neuro-differentiation-promoting activity for individualized brain repair of severe ischemic stroke被引量:4
《Bioactive Materials》2021年第7期1988-1999,共12页Jian Wang Xiaolin Li Yu Song Qiangfei Su Xiakeerzhati Xiaohalati Wen Yang Luming Xu Bo Cai Guobin Wang Zheng Wang Lin Wang 
This work was supported by the National Key Basic Research Program of China[2015CB5540007];the National Natural Science Foundation of China[81671904,81572866,81773104,and 81873931];the Science and Technology Program of Chinese Ministry of Education[113044A];the Major Scientific and Technological Innovation Projects in Hubei Province[2018ACA136];the Integrated Innovative Team for Major Human Diseases Program of Tongji Medical College of HUST;the Academic Doctor Supporting Program of Tongji Medical College of HUST.
Severe ischemic stroke damages neuronal tissue,forming irregular-shaped stroke cavities devoid of supporting structure.Implanting biomaterials to provide structural and functional support is thought to favor ingrowth ...
关键词:Stroke cavities Silk sericin scaffolds Shape-memory properties INJECTABILITY Neuronal differentiation 
Irregular surface of carotid atherosclerotic plaque is associated with ischemic stroke: a magnetic resonance imaging study被引量:17
《Journal of Geriatric Cardiology》2019年第12期872-879,共8页Dan ZHOU Jin LI Dong LIU Li-Ya JI Na-Qin WANG Jie DENG Ji-Chen WANG Min YE Xi-Hai ZHAO 
supported by the National Natural Science Foundation of China (No. 81771825);Beijing Municipal Science and Technology Commission (D1711000 03017003);Ministry of Science and Technology of China (2017YFC1307904)
Objective To determine the association between the irregularity of carotid plaque surface using multidimensional magnetic resonance imaging(MRI) of ipsilateral acute cerebral infarction(ACI) cases. Methods Patients wi...
关键词:ATHEROSCLEROSIS Carotid artery Magnetic resonance imaging Surface irregularity 
Newly detected atrial fibrillation is associated with cortex-involved ischemic stroke
《Chinese Medical Journal》2019年第17期2053-2058,共6页Shu-Ya Li Xiao-Meng Yang Xing-Quan Zhao Li-Ping Liu Yi-Long Wang Yong Jiang Yong-Jun Wang 
Background: Both cortical and cortical-subcortical (cortex-involved) lesions are typically associated with embolic stroke, of which atrial fibrillation (AF) is the common cause. The aim of this study was to find out t...
关键词:ATRIAL FIBRILLATION ISCHEMIC stroke PROLONGED ELECTROCARDIOGRAPH monitoring Magnetic resonance imaging 
Comparative study of the effects of Danhong injection with different doses on ischemic stroke: A substudy of hospital-based Danhong injection registry被引量:4
《Journal of Traditional Chinese Medicine》2018年第6期917-925,共9页Du Yawei Wang Xiaoxia Zhong Liqun Wu Shengxian 
Supported by a Grant(National Science and Technology Major Project for Significant New Drugs Development:"Establishment of Innovative Drug Development Platform",No.2011ZX09302-006-01)from the Ministry of Science and Technology of China
OBJECTIVE: To compare the effects of Danhong injection(DHI) with different doses on ischemic stroke.METHODS: Chinese hospital registered DHI study is a perspective observational study, in which a total of 1292 patient...
关键词:Stroke ENDOTHELIN-1 DANHONG injection Clinical TRIAL 
Regional brain structural abnormality in ischemic stroke patients:a voxel-based morphometry study被引量:3
《Neural Regeneration Research》2016年第9期1424-1430,共7页Ping Wu Yu-mei Zhou Fang Zeng Zheng-jie Li Lu Luo Yong-xin Li Wei Fan Li-hua Qiu Wei Qin Lin Chen Lin Bai Juan Nie San Zhang Yan Xiong Yu Bai Can-xin Yin Fan-rong Liang 
financially supported by the National Program on Key Basic Research Project of China(973 Program);No.2012CB518501;the National Natural Science Foundation of China,No.81072864
Our previous study used regional homogeneity analysis and found that activity in some brain areas of patients with ischemic stroke changed significantly. In the current study, we examined structural changes in these b...
关键词:nerve regeneration ischemic stroke brain structure abnormality Junctional magnetic resonance imaging gray matter density voxel-based morphometry Fugl-Meyer Motor Assessment nervous fi^nctional deficiency scale functional deficiency NEUROPLASTICITY neuralreorganization neural regeneration 
Acupuncture for ischemic stroke:cerebellar activation may be a central mechanism following Deqi被引量:28
《Neural Regeneration Research》2015年第12期1997-2003,共7页Miao-keng Li Yu-jie Li Gui-feng Zhang Jun-qi Chen Ji-ping Zhang Ji Qi Yong Huang Xin-sheng Lai Chun-zhi Tang 
supported by the National Key Basic Research and Development Plan of China(973 Program),No.2006CB504505,2012CB518504;the"University Students Innovation Experiment Project"in Guangdong Province of China,No.1212112038
The needling sensation of Deqi during acupuncture is a key factor of influencing acupuncture outcome.Recent studies have mainly focused on the brain function effects of Deqi in a physiological state.Functional magneti...
关键词:nerve regeneration traditional Chinese medicine ACUPUNCTURE functional magneticresonance imaging ischemic stroke Brodmann area Waiguan (SJ5) acupoint DEQI non-Deqi 973Program neural regeneration 
Deciphering the pharmacological mechanism of the Chinese formula Huanglian-Jie-Du decoction in the treatment of ischemic stroke using a systems biology-based strategy被引量:5
《Acta Pharmacologica Sinica》2015年第6期724-733,共10页Yan-qiong ZHANG Song-song WANG Wei-liang ZHU Yan MA Fang-bo ZHANG Ri-xin LIANG Hai-yu XU Hong-jun YANG 
Aim: Huanglian-Jie-Du decoction (HUDD) is an important multiherb remedy in TCM, which is recently demonstrated to be effective to treat ischemic stroke. Here, we aimed to investigate the pharmacological mechanisms ...
关键词:Traditional Chinese Medicine Chinese herbal formula ischemic stroke Huanglian-Jie-Du decoction systems biology network pharmacology 
A more consistent intraluminal rhesus monkey model of ischemic stroke被引量:6
《Neural Regeneration Research》2014年第23期2087-2094,共8页Bo Zhao Guowei Shang Jian Chen Xiaokun Geng Xin Ye Guoxun Xu Ju Wang Jiasheng Zheng Hongjun Li Fauzia Akbary Shengli Li Jing Lu Feng Ling Xunming Ji 
supported by grants from the National Key Basic Research Program(973 Program)of China,No.2011CB707804;Beijing Municipal Science and Technology Project,No.2121100005312016
Endovascular surgery is advantageous in experimentally induced ischemic stroke because it causes fewer cranial traumatic lesions than invasive surgery and can closely mimic the pathophysiology in stroke patients. Howe...
关键词:nerve regeneration brain injury rhesus monkeys model middle cerebral artery MICROCOIL INFARCTION stroke interventional therapy digital subtraction angiography magnetic resonance image NEUROIMAGING NEUROREGENERATION 
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