supported by the National Key Research&Development Program of China(2022YFC2303900 and 2022YFC3704700);the National Natural Science Foundation of China(32141001 and 31830001);the National Science Fund for Distinguished Young Scholar(32125003);China Postdoctoral Science Foundation(2022M712797).
Fatty acids (FAs) are building blocks required for the threedomains of life. The machinery of type II fatty acid synthesis is longrecognized as a druggable pathway against deadly infections withdrug-resistant bacteria...
supported by the State Basic Research Development Program of China (2014CB932000);the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB14000000);the National Natural Science Foundation of China (21577165, 21425731, 21077128 and 21637004)
During erythroid differentiation,heme-regulated e IF2α kinase(Hri)is necessary to coordinate translation of globin mRNAs with the availability of heme for the production of large amounts of hemoglobin in red blood ce...
Mitogen-activated protein (MAP) kinase is involved in ABA- or H2O2-signaling, and H2O2 acts as inter-mediate in the downstream of ABA signal transduction pathway, which has recently emerged as a secondary mes-senger o...
This work was supported in part by the National Natural Science Foundation of China(Grant No.39925018);the Key Project of the Chinese Academy of Sciences(Grant No.KSCX2-2-01).
Spindle checkpoint is an important biochemical signaling cascade during mitosis which monitors the fidelity of chromosome segregation, and is mediated by protein kinases Mpsl and Bubl/BubRl. Our recent studies show th...
This work was supported by the Special Funds for Major State Basic Research ("973") Project of China (Grang No. Gl 999055902); the Knowledge Innovation Program of the Chinese Academy of Sciences (Grant No. KSCX2-SW-303).
Mitogen-activated protein kinase (MAPK) is a family of Ser/Thr protein kinases expressed widely in eu-karyotic cells. MAPK is activated by a cascade of protein kinase phosphorylation and plays pivotal roles in regulat...
supported by the Chinese Academy of Sciences and the National"973"Program(Grant No.G19990559)
EG4 cells derived from primordial germ cells (PGCs) of 10.5 d post coitum 129/svJ mouse embryos can be used as a model system for in vitro differentiation study due to their pluripotential development ability. EG4 cel...
the fund of Chinese Academy of Sciences (Grant No. KJ952-S1-15).
A non-radioisotopic method was developed for the assay of epidermal growth factor receptor (EGFR). A peptide with twenty amino acid residues around Tyr 1173, the major phosphorylation site of EGFR, was cloned as a GST...
This work was supported in part by the National Science Fund for Outstanding Youth (Grant No. 39725015); the National Natural Science Foundation of China (Grant No. 39780015); the National Basic Research Program (Grant No. G19990116) ;and the National
The existence of Ca2+/calmodulin-dependent kinase (CaM kinase, CaMK) in tobacco is verified immuno-logically and its distribution in different tissues of tobacco is studied. It has been demonstrated that CaMK is mainl...
Protein kinase B (PKB) is a member of the second messenger-regulated subfamily of protein kinases, and plays a key role in cell-cycle regulation, glucose uptake and promotion of cell differentiation. Evidence shows th...
Drought, high salt and cold are three different kinds of environment stresses that severely influence the growth, development and productivity of crops. They all decrease the water state of plant cells, and consequent...