COREPRESSOR

作品数：12被引量：25H指数：3
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相关领域：医药卫生生物学更多>>
相关机构：广州军区广州总医院上海交通大学更多>>
相关期刊：《Cellular & Molecular Immunology》《癌症》《Chinese Medical Journal》《Neural Regeneration Research》更多>>
相关基金：国家自然科学基金更多>>
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Alpha-synuclein-induced upregulation of SKI family transcriptional corepressor 1: A new player in aging and Parkinson's disease?
《Neural Regeneration Research》2026年第1期320-321,共2页Lauren Barrett Rebekah Bevans Aideen M.Sullivan Louise M.Collins Gerard W.O’Keeffe 
supported by Science Foundation Ireland (Grant 19/FFP/6666),Cure Parkinson’s (Grant CP:GO01);a PhD studentship from the Anatomical Society。
SKI family transcriptional corepressor 1(SKOR1also known as LbxCor1, Fussel15, or CORL1), is a member of the SKI family of proteins and is transcribed from a protein-coding gene located on chromosome 15 in humans, tha...
关键词：Alpha Cor AGING 
Lycium barbarum L.-Derived miR162a Functions on Osteoporosis Through Directly Promoting Osteoblast Formation
《Engineering》2025年第3期162-171,共10页Chunyan Gu Xichao Yu Xiaozhu Tang Leilei Gong Jingquan Tan Yuanjiao Zhang Huili Zheng Ze Wang Chenqian Zhang Yejin Zhu Zuojian Zhou Heming Yu Kai Xu Jinao Duan Xiaosong Gu Ye Yang 
supported by Key Project of Jiangsu Province’s Administration of Traditional Chinese Medicine(ZD202203);Jiangsu Province’s Innovation Program(JSSCTD202142);a project funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions(traditional Chinese medicine).
Traditional Chinese medicine(TCM)can help prevent or treat diseases;however,there are few studies on the active substances of TCM.For example,Lycium barbarum L.has been proven to be effective in treating osteoporosis ...
关键词：Traditional Chinese medicine Lycium barbarum L. miR162a OSTEOPOROSIS Nuclear receptor corepressor Transgenic plants 
Regulation of jasmonate signaling by reversible acetylation of TOPLESS in Arabidopsis被引量：10
《Molecular Plant》2022年第8期1329-1346,共18页Chunpeng An Lei Deng Huawei Zhai Yanrong You Fangming Wu Qingzhe Zhai Alain Goossens Chuanyou Li 
This work was supported by the founding from National Natural Science Foundationof China(32161133018,31730010,31991183,31900243);the Strategic Priority Research Program of theCAS(XDPB16);C.A.was supported by the National Postdoctoral Program for Innovative Talents(BX20180355);the postdoctoral fellowship from China PostdoctoralScienceFoundation.
The plant hormone jasmonate(JA)regulates plant immunity and adaptive growth by orchestrating a genome-wide transcriptional program.Key regulators of JA-responsive gene expression include the master transcription facto...
关键词：jasmonate signaling transcriptional repression TOPLESS corepressor GCN5 HDA6 ACETYLATION 
TLE4 acts as a corepressor of Hes1 to inhibit inflammatory responses in macrophages
《Protein & Cell》2019年第4期300-305,共6页
Macrophages play a key role in maintaining homeostasis and in mounti ng compete nt immune responses.Upon stimulation,one of the key effector functions of activated macrophages is production of inflammatory cytokines i...
关键词：MACROPHAGES KEY role compete 
The HDAC3 enzymatic activity regulates skeletal muscle fuel metabolism被引量：3
《Journal of Molecular Cell Biology》2019年第2期133-143,共11页Shiyan Song Yefei Wen Hui Tong Emanuele Loro Yingyun Gong Jidong Liu Sungguan Hong Lei Li Tejvir S.Khurana Maoping Chu Zheng Sun 
Histone deacetylase 3 (HDAC3) is a major HDAC, whose enzymatic activity is targeted by small molecule inhibitors for treating a variety of conditions. However, its enzymatic activity is largely dispensable for its fun...
关键词：HDAC muscle METABOLISM nuclear receptor COREPRESSOR HISTONE DEACETYLATION 
Corepressor metastasis-associated protein 3 modulates epithelial-to-mesenchymal transition and metastasis被引量：5
《Chinese Journal of Cancer》2017年第3期139-149,共11页Liang Du Zhifeng Ning Fuxing Liu Hao Zhang 
supported in part by the National Natural Science Foundation of China(Nos.81071736,30973508,and 81572876);the Clinical Research Enhancement Initiative of Shantou University Medical College(Nos.201412 and 201421);the Collaborative and Creative Center,Molecular Diagnosis and Personalized Medicine,Shantou University,Guangdong Province,and the Department of Education,Guangdong Government under the Top-tier University Development Scheme for Research and Control of Infectious Diseases(Nos.2015072,2015065,2015020,and 2015077)
Worldwide,metastasis is the leading cause of more than 90%of cancer-related deaths.Currently,no specific therapies effectively impede metastasis.Metastatic processes are controlled by complex regulatory networks and t...
关键词：METASTASIS associated PROTEINS COREGULATOR NuRD complex Master REGULATOR 
SHP limits TLR signaling, an inducible transcriptional corepressor被引量：2
《Cellular & Molecular Immunology》2011年第6期445-446,共2页Jiyan Zhang Beifen Shen 
Toll-like receptor(TLR)signaling stimulated by diverse microbial components plays a pivotal role in innate immunity by eliciting a powerful proinflammatory response that is essential for pathogen elimination.However,u...
关键词：immunity endogenous MAINTAIN 
Exchange of a nuclear corepressor between NF-kB and CREB mediates inhibition of phosphoenolpyruvate carboxykinase transcription by NF-kB
《Chinese Medical Journal》2010年第2期221-226,共6页YAN Jin-hua GAO Zhan-guo YE Jian-ping WENG Jian-ping 
This study was supported by grants from the National Natural Science Foundation of China （No. 30570885）, 973 Program of China （No. 2006CB503902） （to WENG Jian-ping）, the National Institutes of Health Grant （No. DK068036） and American Diabetes Association Research Award （No. 7-04-RA-139） （to YE ,lian-ping）Acknowledgements： We would like to be grateful to Ms. Wei Tseng, Dr. HE Qin and Dr. YIN Jun for their excellent technical assistance.
Background NF-KB p65 was shown to inhibit transcription of phosphoenolpyruvate carboxykinase （PEPCK）, a rate-limiting enzyme in gluconeogenesis in the liver. To understand the mechanism of action of NF-KB p65, we in...
关键词：phosphoenolpyruvate carboxykinase NF-kappa B nuclear receptor corepressor 1 
Nuclear corepressor 1 expression predicts response to first-line endocrine therapy for breast cancer patients on relapse被引量：4
《Chinese Medical Journal》2009年第15期1764-1768,共5页ZHANG Zhen-huan Hiroko Yamashita Tatsuya Toyama Yutaka Yamamoto Teru Kawasoe Mutsuko lbusuki Saori Tomita Hiroshi Sugiura Shunzo Kobayashi Yoshitaka Fujii Hirotaka Iwase 
Background Estrogen receptor alpha （ER α） is the most important endocrine therapy responsiveness predictor for women with breast cancer. The accuracy of the prediction of the response to endocrine therapy was thoug...
关键词：breast cancer estrogen receptor nuclear corepressor 1 progesterone receptor PROGNOSIS 
The adenoviral E1A protein relieves gene repression by receptors in v/vo displaces corepressors and unliganded thyroid hormone
《Cell Research》2009年第6期783-792,共10页Yukiyasu Sato Andrew Ding Rachel A Heimeier Ahmed F Yousef Joe S Mymryk Paul G Walfish Yun-Bo Shi 
The human adenovirus type 5 early region 1A （E1A） is one of two oncogenes present in the adenovirus genome and functions by interfering with the activities of cellular regulatory proteins. The E1A gene is alternativ...
关键词：adenoviral E1A thyroid hormone receptor COREPRESSOR COACTIVATOR CHROMATIN 
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