云南高校图书馆联盟文献共享服务平台- S-ADENOSYLMETHIONINE

S-ADENOSYLMETHIONINE: 作品数：23被引量：101H指数：6; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：赵国屏贺英刘权焰丁晓明张欣城更多>>; 相关机构：武汉大学复旦大学中国药科大学山西师范大学更多>>; 相关期刊：《World Journal of Hepatology》《癌症》《Neuroscience Bulletin》《Journal of Environmental Sciences》更多>>; 相关基金：国家自然科学基金福建省自然科学基金更多>>

ROS-induced metabolic reprogramming to one-carbon metabolism and S-adenosylmethionine-mediated epigenetic modification in IL-10-producing B cells for the resolution of pneumonia: 《Cellular & Molecular Immunology》2024年第2期203-204,共2页Sujin Lee Tae Jin Kim; B cells have an essential immunoregulatory function,which is mediated by the secretion of IL-10 and TGFβand interaction with activated CD4^(+)T cells.This antibody-independent function of B cells contributes to ameli...; 关键词：METABOLISM PNEUMONIA IMMUNOLOGY

Methylation in hangtaimycin biosynthesis and its antibacterial activities: 《Synthetic and Systems Biotechnology》2023年第4期682-687,共6页Minghe Luo Yulu Dong Zixin Deng Yuhui Sun; supported by National Key R&D Program of China(2018YFA0903200);General Program of National Natural Science Foundation of China(32370083);Natural Science Foundation of Chongqing CSTB(CSTB2022NSCQ-MSX0995);Graduate Innovation Program(GZLCX20232114)。; About two-thirds of small molecule drugs contain methyl group and it plays a very important role in the drug development.So,methyltransferases catalyzing the methylation have always attracted great attention.Hangtaimy...; 关键词：Hangtaimycin METHYLATION S-Adenosylmethionine-dependent METHYLTRANSFERASES FK506 methyltransferase type O-methyltransferase Antibacterial BIOSYNTHESIS

Coculture engineering for efficient production of vanillyl alcohol in Escherichia coli被引量：2: 《aBIOTECH》2022年第4期292-300,共9页Meichen Yang Hao Meng Xianglai Li Jia Wang Xiaolin Shen Xinxiao Sun Qipeng Yuan; supported by National Key Research and Development Program of China(2018YFA0901800);National Natural Science Foundation of China(21978015);Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(TSBICIP-KJGG-009).; Vanillyl alcohol is a precursor of vanillin,which is one of the most widely used flavor compounds.Currently,vanillyl alcohol biosynthesis still encounters the problem of low efficiency.In this study,coculture engineer...; 关键词：Vanillyl alcohol Coculture engineering Modular optimization METHYLATION S-ADENOSYLMETHIONINE

Effects of S-adenosylmethionine on production of secondary metabolites in Streptomyces diastatochromogenes 1628: 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2021年第9期767-773,共7页Yefeng HU Juan WANG Jie XU Zheng MA Andreas BECHTHOLD Xiaoping YU; supported by the Excellent Youth Fund of Zhejiang Province,China(No.LR17C140002)。; Streptomyces are famous for their ability to synthesize a large number of bioactive compounds as secondary metabolites containing antibiotics,enzyme inhibi-tors,and other small molecules with potential physiological a...; 关键词：SYNTHESIS SYNTHESIZE ochro

An enhanced chemopreventive effect of methyl donor S-adenosylmethionine in combination with 25-hydroxyvitamin D in blocking mammary tumor growth and metastasis被引量：1: 《Bone Research》2020年第3期300-311,共12页Niaz Mahmood Ani Arakelian William J.Muller Moshe Szyf Shafaat A.Rabbani; Therapeutic targeting of metastatic breast cancer still remains a challenge as the tumor cells are highly heterogenous and exploit multiple pathways for their growth and metastatic spread that cannot always be targete...; 关键词：METASTASIS VITAMIN inhibited

Early treatment efficacy of S-adenosylmethionine in patients with intrahepatic cholestasis: A systematic review被引量：11: 《World Journal of Hepatology》2020年第2期46-63,共18页Mazen Noureddin Suntje Sander-Struckmeier JoséM Mato; BACKGROUND S-adenosylmethionine(AdoMet)is a metabolically pleiotropic molecule used to treat intrahepatic cholestasis(IHC)and chronic liver diseases.While the efficacy of AdoMet has been demonstrated previously,it has...; 关键词：S-ADENOSYLMETHIONINE Intrahepatic cholestasis Chronic liver disease Liver enzymes Symptoms of cholestasis

Methionine adenosyltransferases in liver cancer被引量：11: 《World Journal of Gastroenterology》2019年第31期4300-4319,共20页Ben Murray Lucia Barbier-Torres Wei Fan JoséM Mato Shelly C Lu; National Institutes of Health,NIAAA,No.R01AA026759(Lu);National Institutes of Health,NIDDK,No.R01DK107288(Lu);National Institutes of Health,NCCIH,No.R01AT001576;National Institutes of Health,NCI,No.R01CA172086(Lu and Mato);Agencia Estatal de Investigación MINECO,No.SAF 2017-88041-R;ISCiii PIE14/00031,No.CIBERehdISCiii;Severo Ochoa Excellence Accreditation,No.SEV-2016-0644)(Mato); Methionine adenosyltransferases(MATs)are essential enzymes for life as they produce S-adenosylmethionine(SAMe),the biological methyl donor required for a plethora of reactions within the cell.Mammalian systems express...; 关键词：METHIONINE adenosyltransferases S-ADENOSYLMETHIONINE Liver cancer HEPATOCELLULAR carcinoma CHOLANGIOCARCINOMA Biomarkers THERAPEUTIC targets

Biomarkers and subtypes of deranged lipid metabolism in nonalcoholic fatty liver disease被引量：33: 《World Journal of Gastroenterology》2019年第24期3009-3020,共12页José M Mato Cristina Alonso Mazen Noureddin Shelly C Lu; Nonalcoholic fatty liver disease(NAFLD)is a heterogeneous and complex disease that is imprecisely diagnosed by liver biopsy.NAFLD covers a spectrum that ranges from simple steatosis,nonalcoholic steatohepatitis(NASH)w...; 关键词：S-ADENOSYLMETHIONINE Methionine adenosyltransferase Lipid METABOLISM Multiomics LIPIDOMICS NONALCOHOLIC STEATOHEPATITIS One-carbon METABOLISM Very low-density LIPOPROTEINS Steatosis Precision medicine

PDRG1 at the interface between intermediary metabolism and oncogenesis被引量：3: 《World Journal of Biological Chemistry》2017年第4期175-186,共12页Maríaángeles Pajares; support by the Ministerio Educación y Ciencia;Ministerio de Economía y Competitividad of Spain(until June 2013); PDRG1 is a small oncogenic protein of 133 residues. In normal human tissues, the p53 and DNA damageregulated gene 1(PDRG1) gene exhibits maximal expression in the testis and minimal levels in the liver. Increased expr...; 关键词：Epigenetic modifications GLUTATHIONE Methylation ONCOGENES Intermediary metabolism p53 and DNA damage-regulated gene 1 Protein complexes R2TP/prefoldin complex S-adenosylmethionine synthesis Redox stress

Methionine adenosyltransferases in liver health and diseases被引量：5: 《Liver Research》2017年第2期103-111,共9页Komal Ramani Shelly C.Lu; This work was supported by USA National Institutes of Health(NIH)grants R01DK51719(SC Lu)and R01DK107288(SC Lu and K Ramani).; Methionine adenosyltransferases(MATs)are essential for cell survival because they catalyze the biosynthesis of the biological methyl donor S-adenosylmethionine(SAMe)from methionine and adenosine triphosphate(ATP).Mamm...; 关键词：Methionine adenosyltransferases S-ADENOSYLMETHIONINE Liver injury Hepatocellular carcinoma

S-ADENOSYLMETHIONINE