Background:Digestive system cancers constitute a significant number of cancer cases,but their burden is not uniform.As Global Cancer Observatory(GLOBOCAN)2022 has recently updated its estimates of cancer burden,we aim...
Chinese Acadmy of Medical Sciences Innovation Fund for Medical Sciences(CIFMS 2021-1-I2M-003);PUMCH National High-Level Hospital Clinical Research Funding(Nos.2022-PUMCH-C-026,2022-PUMCH-D-002,2022-PUMCH-B-046)
To the Editor:Myelosuppression is one of the most common side effects of chemotherapy.Some patients would develop long-lasting aplastic anemia(AA)even after stopping chemotherapy for over three months,due to persisten...
research grants from the Major Project for Science and Technology Innovation 2025 of Ningbo(No.2019B10037);the K.C.Wong Magna Fund in Ningbo University.
Long non-coding RNAs(lncRNAs)reportedly function as important modulators of gene regulation and malignant processes in the development of human cancers.The lncRNA JPX is a novel molecular switch for X chromosome inact...
This study was supported in part by National Natural Science Foundation of China(No. 81802255);Young Talents in Shanghai(No. 2019 QNBJ);"Dream Tutor" Outstanding Young Talents Program(No. fkyq1901);Clinical Research Project of Shanghai Pulmonary Hospital(No. fk18005);Key Discipline in 2019 (oncology), Project of Shanghai Municipal Science and Technology Commission (Project of Municipal Science and Technology Commission), and Scientific Research Project of Shanghai Pulmonary Hospital(No. fkcx1903)。
Immunotherapy that targets checkpoints, especially programmed cell death protein 1 and programmed cell death ligand 1, has revolutionized cancer therapy regimens. The overall response rate to mono-immunotherapy, howev...
Objective:Evidence suggests that various diseases may contribute to the circular RNAs (circRNAs) expression disorder. This review was aimed at looking for appropriate biomarkers for the treatment of diseases.Data sour...
To the Editor:Leukemia is a malignant proliferative disease that has become the most common malignancy in children,accounting for 40.5%of malignant cancers children.[1]Although chemotherapy can effectively treat child...
To the editor: The recent article by Bao et al' was highly interesting and thought provoking. Interestingly, recent datasuggested that nifedipine may play a major role in oncology to overcome multi-drug resistance.
Background The endoscopic surgery for inner-side cancer of the breast is usually performed by periareolar approach, but it often makes deformation or malposition of nipple and areola. The trans-axillary approach is fa...
Objective To detect the location and geographical features of gene mutation of the cancer based on 30?709 clinical tumor biopsies Methods Thirty thousand seven hundred and nine cases of tumor biopsy mater...
Objectives A group of human mismatch repair (MMR) genes, hMSH2, GTBP, hMLH1, hPMS1, and hPMS2 has been found to be responsible for the inherited susceptibility to colorectal and related cancers. Among the genes, hMSH...