云南高校图书馆联盟文献共享服务平台- N-GLYCANS

N-GLYCANS: 作品数：16被引量：27H指数：3; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：高文杰李恒辉王畅刘欣更多>>; 相关机构：华中科技大学北京大学更多>>; 相关期刊：《Cellular & Molecular Immunology》《Science China(Life Sciences)》《Journal of Pharmaceutical Analysis》《Engineering》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划更多>>

N-glycan biosignatures as a potential diagnostic biomarker for earlystage pancreatic cancer: 《World Journal of Gastrointestinal Oncology》2024年第3期659-669,共11页Yan-Rong Wen Xia-Wen Lin Yu-Wen Zhou Lei Xu Jun-Li Zhang Cui-Ying Chen Jian He; fundings for Clinical Trials from the Affiliated Drum Tower Hospital,Medical School of Nanjing University,No.2021-LCYJ-MS-11.; BACKGROUND Pancreatic ductal adenocarcinoma(PDAC)has a poor prognosis,with a 5-year survival rate of less than 10%,owing to its late-stage diagnosis.Early detection of pancreatic cancer(PC)can significantly increase s...; 关键词：GLYCOMICS N-GLYCANS Biomarkers Pancreatic cancer Predictive modeling

Site-specific N-glycosylation characterization and allergenicity analysis of globulin-1 S allele from wheat: 《Food Science and Human Wellness》2023年第5期1601-1608,共8页Linglin Fu Rongrong Wang Jinru Zhou Chong Wang Yanbo Wang; financially supported by the National Natural Science Foundation of China (31871735)。; N-glycans in many proteins are of great concern because of their strong association with food allergies. Triticum aestivum(bread wheat), a major food crop, is known as one of the “Big Eight” allergenic groups. Howev...; 关键词：Triticum aestivum ALLERGEN GLYCOPROTEIN N-GLYCANS N-GLYCOSYLATION C_(18)-RPLC-MS/MS

系统性红斑狼疮患者的血清IgG糖链特征: 《Engineering》2023年第7期89-98,I0004,共11页潘胡丹王静蓉梁勇王灿坚田瑞敏叶华张晓吴沅皞邵苗张瑞军肖瑶李智张光峰周华王艺霖王晓双栗占国刘维刘良; financially supported by grants from the Macao Science and Technology Development Fund(0003/2019/AKP,0094/2018/A3,and 0010/2020/A1);Guangdong Basic and Applied Basic Research Foundation(2020B1515130005);Guangdong-Hong Kong-Macao Joint Lab on Chinese Medicine and Immune Disease Research,Guangzhou University of Chinese Medicine(2020B1212030006).; 系统性红斑狼疮(systemic lupus erythematosus,SLE)是一种发病机制不明、临床表型异质性大的自身免疫性疾病。目前已有的SLE血清生物标志物灵敏度或特异性有限,使得SLE的早期精准诊断存在困难。在本研究中,通过对389例SLE患者及304例...; 关键词：SYSTEMIC lupuserythematosus N-GLYCANS Diagnostic INDICATORS

可去除染料--N-聚糖多方法深入分析中的缺失环节被引量：2: 《Engineering》2023年第7期132-150,I0006,共20页Samanta Cajic RenéHennig Valerian Grote Udo Reichl Erdmann Rapp; support from the German Federal Ministry of Education and Research(BMBF)under the project“Die Golgi Glykan Fabrik 2.0”(031A557C for Samanta Cajic and Erdmann Rapp);the European Commission(EC)under the project“HighGlycan”(278535 for RenéHennig and Erdmann Rapp);the Deutsche Forschungsgemeinschaft(DFG,German Research Foundation)under the project“The concert of dolicholbased glycosylation:from molecules to disease models”(FOR2509 for Valerian Grote and Erdmann Rapp).; As the roles of glycans in health and disease continue to be unraveled,it is becoming apparent that glycans’immense complexity cannot be ignored.To fully delineate glycan structures,we developed an integrative approa...; 关键词：GLYCOPROTEINS N-GLYCANS Reversible labeling Hydrophilic interaction liquid CHROMATOGRAPHY Capillary gel electrophoresis Mass spectrometry

An innovative method used for the identification of N-glycans on soybean allergenβ-conglycinins被引量：1: 《Food Science and Human Wellness》2023年第3期842-850,共9页Cheng Li Yang Tian Jianli Han Yu Lu Meiyi Zou Yue Jia Chengjian Wang Linjuan Huang Zhongfu Wang; funded by National Natural Science Foundation of China(31870798,31972024);Shaanxi Province Innovation Capability Support Plan-Science and Technology Innovation Team(2020TD-044);Key Laboratory of Glycobiology and Glycoengineering of Xi’an(2019219514SYS010CG032);Natural Science Project of Shaanxi Provincial Department of Education(21JK0929);Science and Technology Resources Sharing Platform Project of Science and Technology Department in Shaanxi Province(2022PT-46)。; β-Conglycinin is one of the major allergens existed in soybean.N-Glycans attached to theβ-conglycinin influenced the immunoreactivity and antigen presenting efficiency ofβ-conglycinin.In this study,we described a n...; 关键词：Soybean allergenβ-conglycinin GLYCOPEPTIDE Mass spectrometry N-GLYCAN Glycosylation site

A Nested Case-Control Study to Explore the Association between Immunoglobulin G N-glycans and Ischemic Stroke被引量：1: 《Biomedical and Environmental Sciences》2023年第5期389-396,共8页WANG Bi Yan SONG Man Shu ZHANG Jie MENG Xiao Ni XING Wei Jia WANG You Xin; supported by grants from the National Natural Science Foundation of China [No.81673247, 81872682;81903401]。; Objective This study prospectively investigates the association between immunoglobulin G(IgG)N-glycan traits and ischemic stroke(IS) risk.Methods A nested case-control study was conducted in the China suboptimal healt...; 关键词：Ischemic stroke Immunoglobulin G N-GLYCANS Nested case-control study

Comparing different domains of analysis for the characterisation of N-glycans on monoclonal antibodies被引量：4: 《Journal of Pharmaceutical Analysis》2020年第1期23-34,共12页Sara Carillo Raquel Peerez-Robles Craig Jakes Meire Ribeiro da Silva Silvia Millan Martín Amy Farrell Natalia Navas Jonathan Bones; With the size of the biopharmaceutical market exponentially increasing,there is an aligned growth in the importance of data-rich analyses,not only to assess drug product safety but also to assist drug development driv...; 关键词：N-GLYCANS BIOPHARMACEUTICALS Monoclonal antibodies Intact mass analysis Mass spectrometry Native mass spectrometry Glycan analysis Peptide mapping Glycopeptide analysis

Two-step derivatization and mass spectral distinction of α2,3 and α2,6sialic acid linkages on N-glycans by MALDI-TOF被引量：1: 《Chinese Chemical Letters》2019年第3期676-680,共5页Xiaoman Zhou Shang Yang Ganglong Yang Zengqi Tan Feng Guan; supported by the National Natural Science Foundation of China (Nos. 81672537 and 81470294);the National Science and Technology Major Project of China (No. 2018ZX10302205);Hundred-Talent Program of Shaanxi Province; Sialylation is one of important glycosylation in human beings and plays an important role in cancer development. α2,3-Linked and α2,6-linked sialic acids are normally observed on the end of N-glycans and have differ...; 关键词：Sialic acid N-GLYCANS DERIVATIZATION MALDI-TOF HYPOXIA

Association between IgG N-glycans and Nonalcoholic Fatty Liver Disease in Han Chinese被引量：2: 《Biomedical and Environmental Sciences》2018年第6期454-458,共5页ZHAO Zhong Yao LIU Di CAO Wei Jie SUN Ming SONG Man Shu WANG Wei WANG You Xin; supported by grants from the National Natural Science Foundation of China[81673247];the National Natural Sciences Foundation of China(NSFC)-Australian National Health and Medical Research Council(NHMRC) Joint Research Project[NSFC 81561128020-NHMRC APP1112767]; Nonalcoholic fatty liver disease（NAFLD） is a major public health issue worldwide. Immunoglobulin G（IgG） N-glycans are associated with risk factors for NAFLD, such as obesity and diabetes. A cross-sectional study i...; 关键词：NAFLD IGG Association between IgG N-glycans and Nonalcoholic Fatty Liver Disease in Han Chinese FBG

Trimming of N-Glycans by the Golgi-Localized α-1,2-Mannosidases, MNS1 and MNS2, Is Crucial for Maintaining RSW2 Protein Abundance during Salt Stress in Arabidopsis被引量：3: 《Molecular Plant》2018年第5期678-690,共13页Chuanfa Liu Guanting Niu Huchen Zhang Yafei Sun Shubin Sun Fugen Yu Shan Lu Yonghua Yang Jianming Li Zhi Hong; This work was partly supported by grants from the National Natural Science Foundation--Outstanding Youth Foundation of China （grant no. 31322008） and the National Basic Research Program of China （grant no. 2014CB542300） to Z.H.; Asparagine （Asn/N）-Iinked glycans are important for protein folding, trafficking, and endoplasmic reticulum-associated degradation in eukaryotes. The maturation of glycoproteins involves the trimming of mannosyl res...; 关键词：N-GLYCAN Golgi α-mannosidase I salt tolerance ARABIDOPSIS

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