National Natural Science Foundation of China(No.81925018 and 82130049 to J.Zhou;No.82001660 to X.Zheng);China Postdoctoral Science Foundation(No.2021M692406 to X.Zheng).
Neonates are susceptible to inflammatory disorders such as necrotizing enterocolitis(NEC)due to their immature immune system.The timely appearance of regulatory immune cells in early life contributes to the control of...
supported by the Ministry of Science and Innovation of Spain(MCIN/AEI/10.13039/501100011033)[project PID2020-119164RB-I00];CIBERehd is funded by Instituto de Salud CarlosⅢ(ISCⅢ),Spain.PFP is supported by the Ministry of Education of Spain(MCIN/AEI/10.13039/501100011033)[grant FPU17/01995]and TPS by the Asociacion Espanola Contra el Cancer(AECC)-Junta Provincial de Leon,Spain.
Despite pharmacological advances such as lenvatinib approval,therapeutic failure of hepatocellular carcinoma(HCC)remains a big challenge due to the complexity of its underlying molecular mechanisms.Neuropilin-1(NRP1)i...
The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)pandemic has a tremendous impact on the health of millions of people worldwide.Unfortunately,those suffering from previous pathological conditions are mor...
Objective To explore the relationship between the expression of neuropilin-1 (NRP-1) on Treg cells and its ligands semaphorins-3 A (Sema3A),transforming growth factor-β_(1) (TGF-β_(1)) as well as the balance of type...
Neuropilins(NRP1 and NRP2)are multifunctional receptor proteins that are involved in nerve,blood vessel,and tumor development.NRP1 was first found to be expressed in neurons,but subsequent studies have demonstrated it...