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作品数：30被引量：57H指数：4
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相关领域：医药卫生更多>>
相关作者：陈艳梅何静陈亚南赵明明肇丽梅更多>>
相关机构：中国科学院研究生院中国医科大学更多>>
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The potency of N,N′-diphenyl-1,4-phenylenediamine and adiposederived stem cell co-administration in alleviating hepatorenal dysfunction complications associated with type 1 diabetes mellitus in rats
《BIOCELL》2023年第8期1885-1895,共11页HANY M.ABD EL-LATEEF SAFA H.QAHL EMAN FAYAD SARAH A.ALTALHI IBRAHIM JAFRI EL SHAIMAA SHABANA MARWA K.DARWISH REHAB MAHER SAAD SHAABAN SHADY G.EL-SAWAH 
the Deanship of Scientific Research,Vice Presidency for Graduate Studies and Scientific Research at King Faisal University,Saudi Arabia,for financial support under the annual funding track(Grant 3730).
Background:The increasing occurrence of diabetes mellitus(DM)noted worldwide has considerably elicited concern in the recent past.DM is associated with elevated vascular complications,morbidity,mortality,and poor qual...
关键词：Antioxidants Diabetic nephropathy DPPD Oxidative stress Stem cells 
The Acute and Chronic Effects of Co-Administration of Turmeric and Black Pepper Extracts in Genetic Hypertension
《Journal of Biosciences and Medicines》2023年第8期114-128,共15页Ma. Guadalupe Calderón-Gallardo Lilia Castillo-Martínez Samuel Estrada-Soto Itzell A. Gallardo-Ortíz Rafael Villalobos-Molina 
High blood pressure is the main risk factor for cardiovascular diseases, it affects many people worldwide and is a public health problem. This study explored the acute and chronic actions of a mixture of turmeric (95%...
关键词：Curcuma longa L. Peper nigrum L. HYPERTENSION POLYPHENOL SHR 
The use of melittin to enhance transgene expression mediated by recombinant adeno-associated virus serotype 2 vectors both in vitro and in vivo被引量：2
《Journal of Integrative Medicine》2023年第1期106-116,共11页Yi-lin Xie Ji-yao Wang Yun He Xiao-min Yu Qing-yun Zheng Chen Ling Xi-lin Feng Li-qing Zhu 
This work was sponsored by grants from the National Natural Science Foundation of China,(No.81972713 to CL);the Natural Science Foundation of Zhejiang Province(No.LY22H200004 to LZ);the Traditional Chinese Medicine Science and Technology Program Project of Zhejiang Province(No.2021ZB181 to LZ);CL is supported by the Oriental Scholars of Shanghai Universities(No.GZ2020001)。
Objective: Melittin, a cell-penetrating peptide, improves the efficiency of many non-viral gene delivery vectors, yet its application in viral vectors has not been well studied. The non-pathogenic recombinant adeno-as...
关键词：TAAV MELITTIN Capsid engineering CO-ADMINISTRATION Transduction efficiency 
Quercetin and lycopene co-administration prevents oxidative damage induced by d-galactose in mice
《Food Bioscience》2022年第6期577-586,共10页Xuan Chen Jinwen Yu Liufeng Zheng Zeyuan Deng Hongyan Li 
supported by the National Natural Science Foundations of China(Grant No.:21964012);Research Project of State Key Laboratory of Food Science and Technology(Grant No.:SKLF-ZZB-202119);Central Government Guide Local Special Fund Project for Scientific and Technological Development of Jiangxi Province(Grant No.:20221ZDD02001)。
Quercetin and lycopene are strong dietary antioxidants that often co-exist in foods.Here,the cardiac and neuroprotective effects of quercetin and lycopene combination were analyzed in d-galactose-induced oxidative str...
关键词：D-GALACTOSE LYCOPENE QUERCETIN Oxidative stress INFLAMMATION 
Co-administration of Antarctic krill peptide EEEFDATR and calcium shows superior osteogenetic activity
《Food Bioscience》2022年第4期74-80,共7页Yao Liu Songyi Lin Shengjie Hu Di Wang Hui Yao Na Sun 
supported by the LiaoNing Revitalization Talents Program of China(XLYC2007078);the Program for Innovative Talents in Higher Education of Liaoning Province of China(LR2019008).
A specific peptide(EEEFDATR)that is released during the hydrolysis of Antarctic krill contains three glutamic acids that cover calcium-binding ligands,and might act as a potential role in enhancing the osteogenetic ac...
关键词：Antarctic krill peptide CALCIUM CO-ADMINISTRATION Osteogenetic activity 
Co-administration of ursodeoxycholic acid with rosuvastatin/ezetimibe in a non-alcoholic fatty liver disease model
《Gastroenterology Report》2022年第1期440-450,共11页Sang Hyun Seo Da Hyun Lee Yu Seol Lee Kyung Joo Cho Hye Jung Park Hye Won Lee Beom Kyung Kim Jun Yong Park Do Young Kim Sang Hoon Ahn Soo Han Bae Seung Up Kim 
supported by Daewoong Pharmaceutical company,and was supported by a Faculty Research Grant from the Yonsei University College of Medicine(6-2019-0068 to S.H.Bae);by a grant from the Korea Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI);funded by the Ministry of Health&Welfare,Republic of Korea(HI17C0913 and HI16C0257 to S.H.Bae);supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT)(NRF-2022R1A2C2003438 to S.H.Bae,NRF-2021R1C1C2095694 to D.H.Lee);by Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Science,ICT&Future Planning(2019R1A2C4070136 to S.U.Kim).
Background Ursodeoxycholic acid(UDCA),statins,and ezetimibe(EZE)have demonstrated beneficial effects against nonalcoholic fatty liver disease(NAFLD).We investigated the efficacy of the combination of UDCA and the mix ...
关键词：non-alcoholic fatty liver disease non-alcoholic steatohepatitis ursodeoxycholic acid ROSUVASTATIN EZETIMIBE 
Co-administration of platelet-rich plasma and small intestinal submucosa is more beneficial than their individual use in promoting acute skin wound healing被引量：4
《Burns & Trauma》2021年第1期72-82,共11页Xiaoxuan Lei Liuhanghang Cheng Yu Yang Mengru Pang Yunqing Dong Xuanru Zhu Caihong Chen Zexin Yao Gang Wu Biao Cheng Tymour Forouzanfar 
funded by National Natural Science Foundation of China,grant number 81671924,81272105;National Key Research and Development Plan of China,grant number 2017YFC1103301;Health and Medical Treatment Collaborative Innovation Major Special Projects of Guangzhou,grant number 201508020253;Science and Technology Key Project of Guangdong Province,grant number 2014B020212010;Science and Technology Planning Project of Guangdong Province of China,grant number 2015B020233012;Military Medical Innovation Special Projects,grant number 18CXZ029;Zhejiang Provincial Basic Public Welfare Research Project,grant number GJ19H140001;and China’s National Key R&D Programs(NKPs);grant number 2018YFB0407204.
Background:Acute skin wounds may compromise the skin barrier,posing a risk of infection.Small intestinal submucosa(SIS)is widely used to treat acute and chronic wounds.However,the efficacy of SIS to accelerate wound h...
关键词：Small intestinal submucosa Platelet-rich plasma Full-thickness skin defect M1macrophages M2macrophages Animal model wound healing SKIN 
Effects of co-administration of Ganoderma terpenoid extract with chloroquine on inflammatory markers and antioxidant status in Plasmodium berghei-infected mice被引量：1
《Journal of Integrative Medicine》2020年第6期522-529,共8页Olarewaju M.Oluba Oghenerobor B.Akpor Feyikemi D.Adebiyi Sunday J.Josiah Olayinka O.Alabi Ayoola O.Shoyombo Augustine O.Olusola 
Objective:To understand the protective effects of Ganoderma terpenoid extract(GTE)against Plasmodium berghei-malarial infection in mice,the present study was carried out to evaluate the effects of GTE in combination w...
关键词：GANODERMA TERPENES MALARIA Oxidative stress Antioxidants Anti-inflammatory agents 
GSH-responsive SN38 dimer-loaded shape-transformable nanoparticles with iRGD for enhancing chemo-photodynamic therapy被引量：6
《Acta Pharmaceutica Sinica B》2020年第12期2348-2361,共14页Congcong Lin Fan Tong Rui Liu Rou Xie Ting Lei Yuxiu Chen Zhihang Yang Huile Gao Xiangrong Yu 
the financial support from National Natural Science Foundation of China(Nos.81961138009;82071915);Research Funds of Sichuan Science and Technology Department(No.19YYJC2250,China);111 Project(No.B18035,China);Fundamental Research Funds for the Central Universities;Natural Science Foundation of Heilongjiang Province of China(No.YQ2019H004)
Accurate tumor targeting,deep penetration and superb retention are still the main pursuit of developing excellent nanomedicine.To achieve these requirements,a stepwise stimuli-responsive strategy was developed through...
关键词：Shape-transformable SN38 dimer GSH-responsive Chemo-photodynamic therapy iRGD CO-ADMINISTRATION Ce6 Breast cancer 
Pharmacokinetic interaction of Forsythia suspensa extract and azithromycin injection after single and co-intravenous administration in rats被引量：3
《Chinese Journal of Natural Medicines》2020年第3期234-240,共7页LI Xin-Gang NI Jian SHEN Su WANG Xiao-Ping TIAN Jing-Chen 
Azithromycin and Chinese medicine forsythia are often used together to treat pediatric mycoplasma infections in China. We aimed to investigate the pharmacokinetic interaction of Forsythia suspensa extract and azithrom...
关键词：FORSYTHIA suspensa AZITHROMYCIN FORSYTHIASIDE CO-ADMINISTRATION Non-compartmental analysis Population pharmacokinetics PHARMACOKINETIC interaction 
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