ACETYLTRANSFERASES

作品数:8被引量:48H指数:3
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相关领域:医药卫生更多>>
相关期刊:《Neural Regeneration Research》《Journal of Traditional Chinese Medicine》《Chinese Journal of Integrative Medicine》《Acta Pharmacologica Sinica》更多>>
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Exploring the role of N-acetyltransferases in diseases:a focus on N-acetyltransferase 9 in neurodegeneration
《Neural Regeneration Research》2025年第10期2862-2871,共10页Prajakta Deshpande Anuradha Venkatakrishnan Chimata Amit Singh 
supported by 1RO1EY032959-01 and RO1 supplement from NIH,Schuellein Chair Endowment Fund and STEM Catalyst Grant from the University of Dayton(to AS).
Acetyltransferases,required to transfer an acetyl group on protein are highly conserved proteins that play a crucial role in development and disease.Protein acetylation is a common post-translational modification pivo...
关键词:acetyl-coenzyme A Alzheimer’s disease animal models cell death DROSOPHILA eye human disease c-Jun N-terminal kinase signaling N-Acetyltransferases N-acetyltransferase 9 NEURODEGENERATION 
FgHAT2 is involved in regulating vegetative growth, conidiation, DNA damage repair, DON production and virulence in Fusarium graminearum被引量:3
《Journal of Integrative Agriculture》2020年第7期1813-1824,共12页LU Wu-yun YANG Nan XU Zhe DAI Han TANG Shuai WANG Zheng-yi 
This work was supported by the National Key Basic Research and Development Program of China(2013 CB127802).
Histone lysine acetylation is catalyzed by acetyltransferases(HATs), which is important in regulating gene expression and physiological function in eukaryotic cells. HATs can be classified into two main types: A-and B...
关键词:Fusarium graminearum ACETYLTRANSFERASES FgHA T2 PATHOGENICITY 
Effect of Modified Wuzi Yanzong Pill(五子衍宗丸) on Tip60-Mediated Apoptosis in Testis of Male Rats after Microwave Radiation被引量:9
《Chinese Journal of Integrative Medicine》2019年第5期342-347,共6页HU Hai-xiang SUN Jing GAO Ya-jing FANG Hong XU Shao-qiang DONG Jing WEI Li-zhao LUO Shao-bo SHEN Chuan-yun ZHANG Qi-long XIE Ya-lan 
Supported by the National Natural Science Foundation of China(No.30972991);Research Projects of the PLA General Logistics Department,China(No.BWS12J077 and No.BKJ16J010)
Objective: To investigate the effect of a modi?ed Wuzi Yanzong Pill(五子衍宗丸, WZYZP) on the male rats' testis after microwave radiation, as well as its potential mechanism. Methods: Forty-?ve male rats were randomly...
关键词:microwave electromagnetic radiation SPERMATOGENESIS apoptosis HISTONE ACETYLTRANSFERASES 
天然来源的赖氨酸乙酰基转移酶小分子调节剂在治疗学中的意义(英文)
《中国药理学与毒理学杂志》2015年第S1期4-4,共1页TapasKKUNDU 
The altered function of any epigenetic modification also causally affects the physiological homeostasis in different pathophysiological conditions such as cancer,neurodegenerative disorders,diabetes,asthma,COPD etc.Am...
关键词:LYSINE ACETYLTRANSFERASES ARGININE methyltransfera 
Effect of berberine on activity and mRNA expression of N-acetyl transferase in human lung cancer cell line A549被引量:6
《Journal of Traditional Chinese Medicine》2014年第3期302-308,共7页Shengyan Xi Kunhan Chuang Kwangming Fang Yimin Lee Jinggung Chung Yaochen Chuang 
Supported by Xiamen Science and Technology Key Program Plan Grant(No.3502Z20100006);Scientific Research Starting Foundation for New Teacher of Xiamen University(No.ZK1014)
OBJECTIVE: To study the effects of berberine on ac- tivity and mRNA expression of N-acetyltransferase in human lung cancer cell line A549. METHODS: N-acetyltransferase antibodies wereprepared. The human lung cancer ...
关键词:BERBERINE ACETYLTRANSFERASES Cell line tumor NEOPLASMS 
Alcohol-induced protein hyperacetylation: Mechanisms and consequences被引量:3
《World Journal of Gastroenterology》2009年第10期1219-1230,共12页Blythe D Shepard Pamela L Tuma 
Supported by The National Institute of Alcohol Abuse and Alcoholism (R21 AA015683) awarded to P.L.T.
Although the clinical manifestations of alcoholic liver disease are well-described, little is known about the molecular basis of liver injury. Recent studies have indicated that ethanol exposure induces global protein...
关键词:ETHANOL HEPATOTOXICITY ACETYLATION DEACETYLASES ACETYLTRANSFERASES 
N-Acetyltransferase 2 gene polymorphism in a group of senile dementia patients in Shanghai suburb被引量:2
《Acta Pharmacologica Sinica》2004年第9期1112-1117,共6页Wei-chaoGUO Guo-fangLIN Yong-linZHA Ke-jianLOU Qing-wenMA Jian-huaSHEN 
ProjectsupportedbytheStateKeyBasicResearchandDevel-opmentProgrammeofChina(973,No,2002CB512900)Ger-manFederalMinistryofEducationandResearch(BMBF,ProjectNoCHN-112-99)
AIM: To investigate the possible association of hereditary polymorphism of N-acetyltransferase 2 (NAT2) gene with the susceptibility towards senile dementia in farmer population of Shanghai suburb. METHODS: NAT2 gene ...
关键词:N-acetyltransferases 2 GENOTYPE Alzheimer disease polymorphism (genetics) 
Effects of histone acetylation and DNA methylation on p21^(WAF1)regulation被引量:25
《World Journal of Gastroenterology》2002年第3期400-405,共6页FangJY LuYY 
Cell cycle progression is regulated by interactions between cyclins and cyclin-dependent kinases (CDKs). p21(WAF1) is one of the CIP/KIP family which inhibits CDKs activity. Increased expression of p21(WAF1) may play ...
关键词:DNA Methylation DNA-Binding Proteins Acetylation ACETYLTRANSFERASES Base Sequence Basic Helix-Loop-Helix Transcription Factors Cell Cycle Proteins Cell Transformation  Neoplastic CpG Islands Cyclin-Dependent Kinase Inhibitor p21 CYCLINS DNA Histone Acetyltransferases HISTONES Humans Molecular Sequence Data Nuclear Proteins Signal Transduction Sp1 Transcription Factor TRANS-ACTIVATORS Transcription Factors 
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