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ΚB: 作品数：1153被引量：4774H指数：22; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：尹文黄跃生李志清徐永健王勇更多>>; 相关机构：华中科技大学武汉大学中南大学中国医科大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金国家教育部博士点基金更多>>

Baicalin Antagonizes Prostate Cancer Stemness via Inhibiting Notch1/NF-κB Signaling Pathway被引量：4: 《Chinese Journal of Integrative Medicine》2023年第10期914-923,共10页WU Ming-hui WU Kun ZHU Yuan-bing LI Da-chuan YANG Huan ZENG Hong; the Science and Health Joint Chinese Medical Research Project of Chongqing Municipal Health Committee(No.2019ZY023447)。; Objective To investigate the molecular mechanisms underlying the effect of baicalin on prostate cancer(PCa)progression both in vivo and in vitro.Methods The in situ PCa stem cells(PCSCs)-injected xenograft tumor model...; 关键词：BAICALIN prostate cancer cancer stemness Notch1/nuclear factorκB signaling

Andrographolide Inhibits Proliferation and Promotes Apoptosis in Bladder Cancer Cells by Interfering with NF-κB and PI3K/AKT Signaling In Vitro and In Vivo被引量：6: 《Chinese Journal of Integrative Medicine》2022年第4期349-356,共8页XUAN Lei HU Jing-hai BI Ran LIU Si-qi WANG Chun-xi; Supported by Science and Technology Department of Jilin Province(No.20190905001SF)。; Objective:To explore the influences of andrographolide(Andro)on bladder cancer cell lines and a tumor xenograft mouse model bearing 5637 cells.Methods:For in vitro experiments,T24 cells were stimulated with Andro(0-40...; 关键词：ANDROGRAPHOLIDE Chinese medicine bladder cancer nuclear factorκB PI3K-AKT

Initiation of Acupoint Molecular Mechanisms for Manual Acupuncture Analgesia—Nuclear FactorκB Signaling Pathway被引量：5: 《Chinese Journal of Integrative Medicine》2021年第12期933-939,共7页ZHANG Kuo ZHAO Xue YANG Tao ZHANG Yan-fang YAN Ya-wen XU Zhi-fang GONG Yi-nan LIU Yang-yang GUO Yong-ming GUO Yi; the China Postdoctoral Science Foundation(No.2019M651044);the National Natural Science Foundation of China(No.81330088)。; Objective To identify the prominent molecular signaling in acupoints and explore their roles in initiating the analgesia effect of manual acupuncture(MA).Method A three-step study was conducted,the experiment 1 was a ...; 关键词：manual acupuncture ACUPOINT ANALGESIA nuclear factor kappa B

Opposite Modulatory Effects of Crataegus aronia Aqueous Extract on Platelet Aggregation in Rats被引量：1: 《Chinese Journal of Integrative Medicine》2021年第9期696-704,共9页Abdullah S.Shatoor Ali Shati S.Al Humayed Sultan AL-Qahtani Mahmoud Alkhateeb; Supported by the Deanship of Scientific Research at King Khalid University,Saudi Arabia (No. R.G.P.1/41/39)。; Objectives:To reveal the mechanisms behind the dual effects of Crataegus aronia(C.aronia)aqueous extract on platelet aggregation by focusing on function,regulation,expression,and signaling of platelets P_(2)Y_(12)rece...; 关键词：Crataegus aronia PLATELETS AGGREGATION P_(2)Y_(12) Intracellular cyclic adenosine monophosphate reactive oxygen species nuclear factorκB

Protective Effect of Hydroxysafflor Yellow A on Inflammatory Injury in Chronic Obstructive Pulmonary Disease Rats被引量：14: 《Chinese Journal of Integrative Medicine》2019年第10期750-756,共7页JIN Ming XUE Chang-jiang WANG Yu DONG Fang PENG Yuan-yuan ZHANG Ya-dan ZANG Bao-xia TAN Li; Supported by the National Natural Science Foundation of China(No.81270103);the Natural Science Foundation of Beijing(No.7132047);the Project of Integrated Traditional Chinese Medicine-Western Medicine Institute of Heart Lung and Blood Vessel Diseases; Objective: To investigate the attenuating effect of Hydroxysafflor yellow A(HSYA) on inflammatory injury in chronic obstructive pulmonary disease(COPD). Methods: Rats were randomly assigned to 7 groups according to bo...; 关键词：Hydroxysafflor YELLOW A chronic OBSTRUCTIVE pulmonary disease inflammation p38 mitogenactivated protein KINASE nuclear factor-κB

Electroacupuncture Delays Cartilage Degeneration by Modulating Nuclear Factor-κB Signaling Pathway被引量：13: 《Chinese Journal of Integrative Medicine》2019年第9期677-683,共7页WU Guang-wen CHEN Jun HUANG Yun-mei PAN Cai-bin CHEN Wen-lie ZHANG Shi-mao LIN Wei LIU Xian-xiang WU Ming-xia; Supported by National Natural Science Foundation of China(No.81373719);Project of Fujian Provincial Development and Reform Commission(No.2014-514);Major Project of Fujian Provincial Department of Science and Technology Agency(No.2013Y4003); Objective: To illustrate the molecular mechanisms underlying the therapeutic effects of electroacupuncture(EA) on knee osteoarthritis(OA). Methods: Twenty-seven six-month-old New Zealand white rabbits were allocated i...; 关键词：OSTEOARTHRITIS ELECTROACUPUNCTURE SYNOVIAL fluid CARTILAGE CYTOKINES nuclear factor-κB signaling pathway

Extract of Fructus Schisandrae chinensis Inhibits Neuroinflammation Mediator Production from Microglia via NF-κB and MAPK Pathways被引量：3: 《Chinese Journal of Integrative Medicine》2019年第2期131-138,共8页SONG Fang-jiao ZENG Ke-wu CHEN Jin-feng LI Yuan SONG Xiao-min TU Peng-fei WANG Xue-mei; Supported by the National Natural Science Foundation of China(No.81173369,81303253 and 81530099);the Natural Science Foundation of Beijing(No.7132210);the Doctoral Scientific Fund Project of the Ministry of Education of China(No.20120001110105); Objective: To investigate the anti-neuroinflammation effect of extract of Fructus Schisandrae chinensis(EFSC) on lipopolysaccharide(LPS)-induced BV-2 cells and the possible involved mechanisms. Methods: Primary cortic...; 关键词：NEUROINFLAMMATION MICROGLIA Fructus Schisandrae CHINENSIS nuclear factor-κB mitogen- activated protein kinase

In Vivo and In Vitro Anti-inflammatory Effects of Ethanol Fraction from Periploca forrestii Schltr.被引量：3: 《Chinese Journal of Integrative Medicine》2017年第7期528-534,共7页DONG Li ZHANG Yun WANG Xia DONG Yong-xi ZHENG Lin LI Yong-jun NI Jing-man; Supported by the National Natural Science Foundation of China(No.81460641,No.81660691); Objective：To determine the anti-inflammatory effects of an ethanol fraction of Periploca forrestii Schltr.（EFPF） and to investigate the potential mechanisms underlying in vivo and in vitro models. Methods：The anti...; 关键词：Periploca forresti Schltr anti-inflammatory effect mitogen-activated protein kinase nuclear factor κB

Panax notoginseng Saponins Protect Kidney from Diabetes by Up-regulating Silent Information Regulator 1 and Activating Antioxidant Proteins in Rats被引量：11: 《Chinese Journal of Integrative Medicine》2016年第12期910-917,共8页杜月光汪丽佩钱俊文章科娜柴可夫; Supported by National Natural Science Foundation of China(No.81273615);Zhejiang Provincial Natural Science Fund(No.Y2110849); Objective： To explore the mechanism of the protective effects of Panax notoginseng saponins（PNS） on kidney in diabetic rats. Methods： Diabetic rat model was obtained by intravenous injection of alloxan, and the ra...; 关键词：Panax notoginseng saponins diabetic nephropathy inflammation nuclear factor κB silent information regulator 1 Chinese medicine

Induction of Adhesion Molecule Expression in Co-culture of Human Bronchial Epithelial Cells and Neutrophils Suppressed by Puerarin via Down-regulating p38 Mitogen-Activated Protein Kinase and Nuclear Factor κB Pathways被引量：3: 《Chinese Journal of Integrative Medicine》2014年第5期360-368,共9页刘野邵玲俐庞伟兰晓梅吕建新丛玉隆王成彬; Supported by the National Natural Sciences Foundation of China(No.30873419); Objective： In this study, we aimed to investigate the expressions of adhesion molecules on human bronchial epithelial cells and neutrophils in co-culture system, assess the effects of puerarin on suppressing these ad...; 关键词：bronchial epithelial cells NEUTROPHILS PUERARIN adhesion molecules p38 mitogen-activatedprotein kinase nuclear factor kappa B

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