OXIDATIVE_STRESS

作品数：1745被引量：7294H指数：30
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Contribution of ferroptosis and SLC7A11 to light-induced photoreceptor degeneration
《Neural Regeneration Research》2026年第1期406-416,共11页Xiaoxu Huang Yumeng Zhang Yuxin Jiang Tong Li Shiqi Yang Yimin Wang Bo Yu Minwen Zhou Guanran Zhang Xiaohuan Zhao Junran Sun Xiaodong Sun 
supported by the National Natural Science Foundation of China,Nos. 82171076 (to XS) and U22A20311 (to XS), 82101168 (to TL);Shanghai Science and technology Innovation Action Plan,No. 23Y11901300 (to JS);Science and Technology Commission of Shanghai Municipality,No. 21ZR1451500 (to TL);Shanghai Pujiang Program,No. 22PJ1412200 (to BY)。
Progressive photoreceptor cell death is one of the main pathological features of age-related macular degeneration and eventually leads to vision loss. Ferroptosis has been demonstrated to be associated with retinal de...
关键词：age-related macular degeneration ferroptosis light exposure damage oxidative stress pathway PHOTORECEPTOR programmed cell death solute carrier family 7 member 11(SLC7A11) 
Acquired sensorineural hearing loss,oxidative stress,and microRNAs
《Neural Regeneration Research》2025年第9期2513-2519,共7页Desmond A.Nunez Ru C.Guo 
Hearing loss is the third leading cause of human disability.Age-related hearing loss,one type of acquired sensorineural hearing loss,is largely responsible for this escalating global health burden.Noise-induced,ototox...
关键词：hearing loss HYPOXIA MICRORNAS oxidative stress SENSORINEURAL 
Hydrogen sulfide reduces oxidative stress in Huntington's disease via Nrf2
《Neural Regeneration Research》2025年第6期1776-1788,共13页Zige Jiang Dexiang Liu Tingting Li Chengcheng Gai Danqing Xin Yijing Zhao Yan Song Yahong Cheng Tong Li Zhen Wang 
supported by the National Natural Science Foundation of China,Nos.82271327 (to ZW),82072535 (to ZW),81873768 (to ZW),and 82001253 (to TL)。
The pathophysiology of Huntington's disease involves high levels of the neurotoxin quinolinic acid. Quinolinic acid accumulation results in oxidative stress, which leads to neurotoxicity. However, the molecular and ce...
关键词：apoptosis CYSTATHIONINE-Β-SYNTHASE nuclear factor erythroid 2-related factor 2 Huntington's disease hydrogen sulfide MITOCHONDRION NEUROPLASTICITY oxidative stress quinolinic acid reactive oxygen species 
Comparison of effects of calcium and chlorogenic acid intervention on bone and intestinal injury in cadmium-exposed growing rats
《Food and Health》2025年第2期24-34,共11页Yu-Na Kan Xiao-Wei Wang Hui-Fang Chen Xiao-Jiao Gao Xiao Huang Jia-Ming Xie 
supported by Guizhou Provincial Basic Research Program(Natural Science)(Qiankeheji-ZK[2021]General 497);Guizhou Health and Wellness Commission Science and Technology Fund Project(2024-247);Guizhou University of Traditional Chinese Medicine Academic Seedling Program(Guizhou Kehe Academic Seedling[2023]-35),The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine Institutional Research Grants(GZEYK[2020-34]).
Background:Cadmium(Cd)exposure disrupts bone microstructure and elevates osteoporosis risk,warranting innovative functional food development to alleviate its toxic effects.This study evaluated the protective effects o...
关键词：CADMIUM CALCIUM chlorogenic acid bone microstructure gut microbiota oxidative stress 
The crosstalk between non-coding RNAs and oxidative stress in cancer progression
《Genes & Diseases》2025年第3期146-167,共22页Qiqi Sun Xiaoyong Lei Xiaoyan Yang 
funded by the Hengyang City Science and Technology Planning Project(Hunan,China)(No.202150063473);the Scientific Research Project of Hunan Provincial Health Commission(China)(No.202202044140);the Scientific Research Project of Hunan Provincial Education Department(China)(No.21B0438).
As living standards elevate,cancers are appearing in growing numbers among younger individuals globally and these risks escalate with advancing years.One of the reasons is that instability in the cancer genome reduces...
关键词：ANGIOGENESIS Autophagy CANCER Cancer energy metabolism Epithelial mesenchymal transformation Non-coding RNAs Oxidative stress 
Fenofibrate mitigates the dysfunction of high glucosedriven human retinal microvascular endothelial cells by suppressing NLRP3 inflammasome
《International Journal of Ophthalmology(English edition)》2025年第5期792-801,共10页Yi Shi Hao-Min Chen Ai-Hua Liu Xiao-Rong Li 
Supported by grants from the Tianjin Key Medical Discipline(Specialty)Construction Project(No.TJYXZDXK-037A).
AIM:To determine the therapeutic benefits of fenofibrate(Feno)on the dysfunction of high glucose(HG)-induced human retinal microvascular endothelial cells(HRMECs)and to elucidate the underlying molecular mechanism.MET...
关键词：FENOFIBRATE human retinal microvascular endothelial cells high glucose NOD-like receptor thermal protein domain associated protein 3 inflammasomes oxidative stress 
Ferulic acid alleviates long-term avermectin-induced damage to the spleen of carp and restores its inflammatory response and oxidative balance
《Journal of Environmental Sciences》2025年第5期616-626,共11页Hanyu Wang Shenye Feng Enzhuang Pan Xiaomeng Ji Mengyuan Zhou Shuai Zhang Baoshi Xu Huimiao Feng Jilei Yin Zibo Dong 
supported by the National Natural Science Foundation of China(No.81773968);the Priority Academic Program Development of Jiangsu Higher Education Institutions of China.
Extensive use of avermectin(AVM)in agriculture can seriously contaminate fish in aquaculture.Ferulic acid(FA)is a strong antioxidant sourced from plants and is widely applied in food and medicine,but its protective fu...
关键词：AVERMECTIN Ferulic acid Oxidative stress Inflammation response 
Tranylcypromine upregulates Sestrin 2 expression to ameliorate NLRP3-related noise-induced hearing loss
《Neural Regeneration Research》2025年第5期1483-1494,共12页Xihang Chen Zhifeng Chen Menghua Li Weiwei Guo Shuolong Yuan Liangwei Xu Chang Lin Xi Shi Wei Chen Shiming Yang 
supported by the National Key Research and Development Program of China,No.2022YFC2402701(to WC);Key International(Regional)Joint Research Program of the National Natural Science Foundation of China,No.81820108009(to SY);the National Natural Science Foundation of China,Nos.81970890(to WC)and 82371148(to WG);Fujian Provincial Healthcare Young and Middle-aged Backbone Talent Training Project,No.2023GGA035(to XC);Spring City Plan;the High-level Talent Promotion and Training Project of Kunming,No.2022SCP001(to SY);the Natural Science Foundation of Hainan Province of China,No.824MS052(to XS);the Sixth Medical Center of Chinese PLA General Hospital Innovation Cultivation,No.CXPY202116(to LX)。
Noise-induced hearing loss is the primary non-genetic factor contributing to auditory dysfunction.However,there are currently no effective pharmacological interventions for patients with noise-induced hearing loss.Her...
关键词：4-HYDROXYNONENAL apoptosis AUTOPHAGY cleaved caspase-3 inflammation NOD-like receptor family pyrin domain-containing 3(NLRP3) noise-induced hearing loss oxidative stress Sestrin2 TRANYLCYPROMINE 
Double-edged sword of L-arginine in diabetes:Exploring antiinflammatory and antioxidant strategies
《World Journal of Diabetes》2025年第4期314-317,共4页Shuai Liu Ning Li Jia-Jia Jin Yong-Wei Yu 
The article by Mansouri et al provides a comprehensive investigation into the effects of L-arginine(L-Arg)on diabetic cardiomyopathy.The authors conclude that while a low dose(0.5 g/kg)of L-Arg improves lipid profiles...
关键词：L-ARGININE Diabetic cardiomyopathy Oxidative stress Nuclear factor erythroid 2-related factor 2 Nitric oxide synthase 
Brassinolide ameliorates the detrimental effects of arsenic in tomato: Insights into iron and arsenic absorption, antioxidant capacity, nitrogen, and sulfur assimilation
《Horticultural Plant Journal》2025年第2期737-757,共21页Abolghassem Emamverdian Abazar Ghorbani Necla Pehlivan James Barker Meisam Zargar Moxian Chen Guohua Liu 
financial support from the National Key Research and Development Program of China(Grant No.2023YFD220120302);supported by RUDN University Strategic Academic Leadership Program。
The role of brassinosteroids(BRs)in enabling plants to respond effectively to adverse conditions is well known,though the precise mechanism of action that helps plants cope with arsenic(As)toxicity is still difficult ...
关键词：Arsenic toxicity BRASSINOSTEROID Fe transporters Nitrogen metabolism Sulfur assimilation Oxidative stress 
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