supported by the National Natural Science Foundation of China(Grant Number:82274194);Jiangsu Natural Science Funds(Grant Number:BK20211224,China);the Project of State Key Laboratory of Natural Medicines(Grant Number:SKLNMZZ202001,China)。
Nonalcoholic steatohepatitis(NASH)is a spectrum of chronic liver disease characterized by hepatic lipid metabolism disorder.Recent reports emphasized the contribution of triglyceride and diglyceride accumulation to NA...
Guangdong Provincial Basic and Applied Basic Research Fund(No.2022A1515012195);Guangdong Provincial Bureau of Traditional Chinese Medicine Research Project(No.20211221,No.20222099);Guangdong Medical University Research Fund(No.4SG20158G)。
Objective:To investigate the effects of Schisandra B on proliferation,migration,invasion of bladder cancer and to further investigate its molecular mechanism.Methods:Bladder cancer cells were subjected to different co...
supported by the National Key Research and Development Program of China(2017YFC1701200),Leading Talents of Science and Technology Innovation in Liaoning Province(XLYC1902101).
The plants of the genus Schisandra belong to the Schisandraceae family.As one of the main active components of genus Schisandra,lignans have rich biological activities,including anti-inflammatory,anti-tumor,anti-HIV a...
This work was supported by the National Key Research and Development Program of China(2017YFC1701200);Leading Talents of Science and Technology Innovation in Liaoning Province(XLYC1902101);Liaoning Provincial Doctoral Research Start-up Fund(2019-BS-224).
The plants of the genus Schisandra of the Schisandraceae family include the genus Schisandra and the genus Kadsura.In recent years,many kinds of triterpenoids have been isolated from the plants of genus Schisandra.Tri...
supported financially by the National Natural Science Foundation of China (No.81903520).
A pair of new tetrahydrofuran lignan enantiomers,(±)-schibiculatin A[(±)-1],a new enedione lignan,schibiculatin B(2),two new cadinane-type sesquiterpenoids,schibiculatins C(3)and D(4),along with two known seco-cadin...
financially supported by the National Natural Science Foundation of China(U1508220);Liaoning DistinguishedProfessor Project for Qing Li(2017,China);Shenyang Pharmaceutical University Innovative Research Team.
Schisandra chinensis,a widely used Chinese herbal medicine,was considered as central nervous system(CNS)drug for years.Both ethanol extracts(EES)and water extracts(WES)of it were applied clinically.Unfortunately,the d...
supported by the Natural Science Foundation of China(Nos.81973392,81573489);the National Key Research and Development Program(No.2017YFE 0109900);the Natural Science Foundation of Guangdong(No.2017A030311018);the 111 project(No.B16047);the Key Laboratory Foundation of Guangdong Province(No.2017B030314030);the Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program(No.2017BT01Y093);the National Engineering and Technology Research Center for New drug Druggability Evaluation(Seed Program of Guangdong Province,No.2017B090903004)。
Cholestasis is caused by the obstacle of bile formation or secretion and can develop into severe liver diseases. We previously reported the ethanol extract of Schisandra sphenanthera(Wuzhi tablet, WZ) can significantl...
Supported by the 2019 Post-Doc.Development Program of Pusan National University
OBJECTIVE:To investigate the effects and molecular targets of Schisandrae Fructus(SF)methanol extract(SFme)in mice with hyperlipidemia induced by high fat diet.METHODS:We observed changes in body weight,blood serum co...
supported by the National Natural Science Foundation of China(No.81903520);the Second Tibetan Plateau Scientific Expedition and Research(STEP)program(No.2019QZKK0502)
Nineteen preschisanartane-type schinortriterpenoids(SNTs),among which eleven ones were previously undescribed,were isolated from two Schisandra species,S.sphaerandra and S.rubriflora.Their structures were determined u...
Objective:To study the immunomodulatory effect of schisandra oil (SCO) in mouse model of autoimmune hepatitis induced by concanavalin A (ConA). Methods: C57BL/6 mice were divided into control group, model group and SC...