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X-BOX: 作品数：25被引量：46H指数：4; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：宋方洲郭风劲郝轶群申凤俊郭俊芝更多>>; 相关机构：北京协和医学院首都医科大学附属北京妇产医院山西医科大学第一医院东南大学更多>>; 相关期刊：《肿瘤研究与临床》《World Journal of Gastroenterology》《新潮电子》《大众软件》更多>>; 相关基金：国家自然科学基金更多>>

Exosomes derived from microglia overexpressing miR-124-3p alleviate neuronal endoplasmic reticulum stress damage after repetitive mild traumatic brain injury: 《Neural Regeneration Research》2024年第9期2010-2018,共9页Yan Wang Dai Li Lan Zhang Zhenyu Yin Zhaoli Han Xintong Ge Meimei Li Jing Zhao Shishuang Zhang Yan Zuo Xiangyang Xiong Han Gao Qiang Liu Fanglian Chen Ping Lei; supported by the Haihe Laboratory of Cell Ecosystem Innovation Fund,No.22HHXBSS00047(to PL);the National Natural Science Foundation of China,Nos.82072166(to PL),82071394(to XG);Science and Technology Planning Project of Tianjin,No.20YFZCSY00030(to PL);Science and Technology Project of Tianjin Municipal Health Commission,No.TJWJ2021QN005(to XG);Tianjin Key Medical Discipline(Specialty)Construction Project,No.TJYXZDXK-006A;Tianjin Municipal Education Commission Scientific Research Program Project,No.2020KJ164(to JZ);China Postdoctoral Science Foundation,No.2022M712392(to ZY).; We previously reported that miR-124-3p is markedly upregulated in microglia-derived exosomes following repetitive mild traumatic brain injury.However,its impact on neuronal endoplasmic reticulum stress following repet...; 关键词：apoptosis C/EBP homologous protein endoplasmic reticulum stress EXOSOME inositol-requiring enzyme 1α MICROGLIA miR-124-3p neuron repetitive mild traumatic brain injury X-box binding protein 1

X-box binding protein 1 caused an imbalance in pyroptosis and mitophagy in immature rats with di-(2-ethylhexyl)phthalate-induced testis toxicity: 《Genes & Diseases》2024年第2期935-951,共17页Yifan Hong Xiazhu Zhou Qi Li Jing Chen Yuexin Wei Chunlan Long Lianju Shen Xiangqin Zheng Dinggang Li Xia Wang Chenjun Yu Shengde Wu Guanghui Wei; supported by the National Natural Science Foundation of China(No.81771566,82071632);the Postgraduate Research Innovation Project of Chongqing Medical University(China)(No.CYB22210);the Youth Basic Research Project from the Ministry of Education Key Laboratory of Child Development and Disorders(China)(No.YBRP-202114).; As a widely used plasticizer,di-(2-ethylhexyl)phthalate(DEHP)is known to induce significant testicular injury.However,the potential mechanism and effects of pubertal exposure to DEHP on testis development remain uncle...; 关键词：DEHP MITOPHAGY PYROPTOSIS Testicular development XBP1

X-box-binding protein 1 is required for pancreatic development in Xenopus laevis: 《Acta Biochimica et Biophysica Sinica》2020年第11期1215-1226,共12页Jing Yang Xingjing Liu Fang Yuan Jia Liu Deli Li Liyuan Wei Xuejun Wang Li Yuan; the grants from the National Natural Science Foundation of China(No.30971680);the Key Project of Natural Science Research in Colleges and Universities of Jiangsu Province(No.17KJA310001).; X-box-binding protein 1(XBP1)is a protein containing the basic leucine zipper structure.It belongs to the cAMP-response element binding protein(CREB)/activating transcription factor transcrip-tion factor family.As the...; 关键词：FoxA2 pancreatic development XBP1 Xenopus laevis

“X-BOX”移动助手: 《设计》2020年第16期18-18,共1页徐明亮; 该设计从地摊经济的出行、运输、展示、商业交易等系列行为特征入手,将滑板车、行李箱和商品展架进行结合设计,以满足现代地摊经济的特定需求。设计特点如下:一、电动充电设计可短途代步,可进行小商品运输;二、可变化展架设计,可水平或...; 关键词：手机充电地摊经济滑板车商业行为行李箱特定需求行为特征商品展示

The unfolded protein response signaling and retinal Müller cell metabolism被引量：2: 《Neural Regeneration Research》2018年第11期1861-1870,共10页Kristen Kelly Joshua J.Wang Sarah X.Zhang; supported,in part,by NIH/NEI grants EY019949 and EY025061;an Unrestricted Grant to the Department of Ophthalmology,SUNY-Buffalo,from Research to Prevent Blindness; The retina is one of the most energy demanding tissues in the body. Like most neurons in the central nervous system, retinal neurons consume high amounts of adenosine-5′-triphosphate（ATP） to generate visual signal ...; 关键词：unfolded protein response RETINA Müller glia metabolism NEURODEGENERATION X-box binding protein 1 glycolysis glucose transporter

Role of X-Box Binding Protein-1 in Fructose-Induced De Novo Lipogenesis in HepG2 Cells被引量：7: 《Chinese Medical Journal》2018年第19期2310-2319,共10页Xian Yu Lu-Ping Ren Chao Wang Ya-Jun Zhu Han-Ying Xing Jing Zhao Guang-Yao Song; Background：A high consumption of fructose leads to hepatic steatosis.About 20-30% of triglycerides are synthesized via de novo lipogenesis.Some studies showed that endoplasmic reticulum stress （ERS） is involved in ...; 关键词：Endoplasmic Reticulum Stress Fatty Liver LIPOGENESIS X-Box Binding Protein-I

miR-30c-2-3p调控X-box结合蛋白-1对大鼠心肌细胞缺氧/复氧损伤的影响被引量：7: 《中华实用诊断与治疗杂志》2018年第3期211-214,共4页李瑞萍薛富善杨桂珍刘亚洋李慧娴廖旭; 国家自然科学基金(81170128);国家自然科学基金(81470019); 目的探讨miR-30c-2-3p调控X-box结合蛋白-1(X box-binding protein-1,XBP1)对大鼠心肌细胞缺氧/复氧损伤的保护作用。方法制备新生大鼠心肌细胞,随机分为对照组、缺氧/复氧组和miR-30c-2-3p处理组。对照组心肌细胞正常培养,缺氧/复氧组...; 关键词：微小RNA 内质网应激缺氧心肌细胞 X-box结合蛋白-1 大鼠

RIDE 2多平台发布: 《摩托车》2016年第11期8-8,共1页; 备受期待的摩托车主题游戏RIDE2近日在PS4、X-box和WindowsPc平台发售。RIDE2延续RIDE的精髓进行完善，拥有超过200款摩托车供玩家选择，改进模型和声音，支持分屏多人游戏和在线多人游戏。同时RIDE2也将对初学者更加友好，更容易上手。; 关键词：多平台 Windows 多人游戏 X-BOX PC平台摩托车初学者声音

未折叠蛋白反应相关因子葡萄糖调节蛋白78、X-盒结合蛋白1在食管癌中的表达及其意义被引量：1: 《肿瘤研究与临床》2016年第10期683-686,共4页赵和平郝轶群张娜申凤俊许翠萍郭俊芝; 目的：探讨未折叠蛋白反应相关因子葡萄糖调节蛋白78（GRP78）及X-盒结合蛋白1（XBP1）在食管鳞状细胞癌中的表达、其对内质网应激（ERS）的激活作用及其在食管癌浸润生长中的作用机制。方法通过免疫组织化学方法检测30例食管鳞状细胞癌...; 关键词：食管肿瘤癌鳞状细胞未折叠蛋白反应葡萄糖调节蛋白78 X-盒结合蛋白1 GLUCOSE regulated PROTEIN 78 X-BOX binding PROTEIN 1

Effects of endoplasmic reticulum stress on the expressionof inflammatory cytokines in patients with ulcerative colitis被引量：4: 《World Journal of Gastroenterology》2016年第7期2357-2365,共9页nan li xue-ming wang li-jun jiang meng zhang na li zhen-zhen wei nan zheng ya-jiao zhao; Beijing Municipal Natural Scientific Research Foundation,No.7132175; AIM: To explore the changes of X-box binding protein 1splicing(XBP1s) and inflammatory cytokine expression in patients with ulcerative colitis(UC) in response to endoplasmic reticulum stress(ERS).METHODS: Reverse tran...; 关键词：ULCERATIVE COLITIS Endoplasmic reticulumstress X-BOX BINDING protein 1 SPLICING

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