ABERRANT

作品数：201被引量：605H指数：12
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相关领域：医药卫生更多>>
相关作者：杨音杨楠孙鸾张欣孙玉洁更多>>
相关机构：第二军医大学第三军医大学西南医院南京医科大学湖州市第三人民医院更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>
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  • 期刊=Neural Regeneration Researchx
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Glutamatergic CYLD deletion leads to aberrant excitatory activity in the basolateral amygdala:association with enhanced cued fear expression
《Neural Regeneration Research》2025年第11期3259-3272,共14页Huidong Li Faqin Li Zhaoyi Chen Erwen Wu Xiaoxi Dai Danni Li Haojie An Shiyi Zeng Chunyan Wang Li Yang Cheng Long 
supported by the National Natural Science Foundation of China,Nos.32371065(to CL)and 32170950(to LY);the Natural Science Foundation of the Guangdong Province,No.2023A1515010899(to CL);the Science and Technology Projects in Guangzhou,Nos.2023A4J0578 and 2024A03J0180(to CW)。
Neuronal activity,synaptic transmission,and molecular changes in the basolateral amygdala play critical roles in fear memory.Cylindromatosis(CYLD)is a deubiquitinase that negatively regulates the nuclear factor kappa-...
关键词：basolateral amygdala cued fear expression cylindromatosis deubiquitinase glutamate receptor 1 glutamatergic neuron microglial activation N-methyl-D-aspartate receptor 1 neuronal activation synaptic transmission 
3'-Deoxyadenosin alleviates methamphetamine-induced aberrant synaptic plasticity and seeking behavior by inhibiting the NLRP3 inflammasome被引量：1
《Neural Regeneration Research》2024年第10期2270-2280,共11页Yize Qi Yao Zhou Jiyang Li Fangyuan Zhu Gengni Guo Can Wang Man Yu Yijie Wang Tengfei Ma Shanwu Feng Li Zhou 
supported by the National Natural Science Foundation of China,No.81971246 (to TM);Opening Foundation of Jiangsu Key Laboratory of Neurodegeneration,Nanjing Medical University,No.KF202204 (to LZ and SF)。
Methamphetamine addiction is a brain disorder characterized by persistent drug-seeking behavior, which has been linked with aberrant synaptic plasticity. An increasing body of evidence suggests that aberrant synaptic ...
关键词：3′-deoxyadenosin hippocampus long-term potentiation METHAMPHETAMINE NOD-like receptor family pyrin domain containing-3(NLRP3)inflammasome synaptic plasticity 
Aberrant adult neurogenesis in intractable epilepsy:can GABAergic progenitor transplantation normalize this process?
《Neural Regeneration Research》2024年第7期1419-1420,共2页Muhammad N.Arshad Janice R.Naegele 
Temporal lobe epilepsy(TLE) is a common type of focal epilepsy characterized by seizure foci within the temporal lobes.While surgical resection of the foci is an established and effective approach for controlling seiz...
关键词：EPILEPSY PROGENITOR seizures 
Cdk5 and aberrant cell cycle activation at the core of neurodegeneration被引量：5
《Neural Regeneration Research》2023年第6期1186-1190,共5页Raquel Requejo-Aguilar 
supported by the Spanish Ministry of Industry and Competitiveness[Grant BFU2016-80006-P];The Andalusian Regional Government[Group BIO-216];the FEDER-Andalusian programme 2014-2020[1262530-R].
Neurodegenerative diseases are caused by the progressive loss of specific neurons.The exact mechanisms of action of these diseases are unknown,and many studies have focused on pathways related to abnormal accumulation...
关键词：Alzheimer´s disease amyotrophic lateral sclerosis apoptosis CDK5 cell cycle Huntington´s disease NEURODEGENERATION neuron oxidative stress Parkinson´s disease signaling Tau phosphorylation 
Psychosis symptoms following aberrant immunity in the brain
《Neural Regeneration Research》2021年第3期512-513,共2页Akitoshi Ozaki Yuki Yamawaki Gen Ohtsuki 
supported by grants from the Kowa Life Science Foundation;the Japanese Society for Promotion of Science(KAKENHI,Grant-in-Aid for Young Scientists(A)26710002);the Brain Science Foundation;the Tokyo Biochemical Research Foundation;the Naito Foundation;the Hakubiproject grant(Kyoto University)(all to GO)。
Neuroinflammation in the brain is thought related to the emergence of various psychoses,although the identifying regional significance,the involvement of immune-cells and lymphocytic activity,and ways for the therapeu...
关键词：INFLAMMATION IMMUNITY INVOLVEMENT 
Aberrant cell cycle induction is pivotal for mitochondrial biogenesis after traumatic brain injury被引量：3
《Neural Regeneration Research》2019年第7期1215-1216,共2页Nilkantha Sen 
Cell cycle regulation and brain injury:Traumatic brain injury(TBI)is one of the primary causes of morbidity and mortality in patients,and it affects more than 1.7 million Americans each year.Other than direct damage r...
关键词：Cell CYCLE brain INJURY direct damage 
Toll-like receptor-4 antagonism mediates benefits during neuroinflammation被引量：2
《Neural Regeneration Research》2016年第4期552-553,共2页Sagar Gaikwad Challagundla Naveen Reena Agrawal-Rajput 
funded by Department of Science and Technology,Government of India (Grant No.SR/CSI/59/2011(G);Gujarat State Biotechnology Mission (Grant No.GSBTM/MD/PROJECTS/.SSA/3385/2012/2013)
Neuroinflammation following immune activation in the central nervous system（CNS）leads to neuronal loss in specific areas of the CNS resulting in neurodegenerative disorders.Thus,fine tuning the immune responses with...
关键词：neuronal tuning inflammation benefits aberrant microglia inappropriate cytokines bidirectional sepsis 
Lipid rafts participate in aberrant degradative autophagic-lysosomal pathway of amyloid-beta peptide in Alzheimer's disease被引量：4
《Neural Regeneration Research》2014年第1期92-100,共9页Xin Zhou Chun Yang Yufeng Liu Peng Li Huiying Yang Jingxing Dai Rongmei Qu Lin Yuan 
supported by a grant from Projects of High-tech Industrialization of Guangdong Province of China,No.2011B010500004;a grant from National Financial Major Project of China
Amyloid-beta peptide is the main component of amyloid plaques, which are found in Alzhei- mer＇s disease. The generation and deposition of amyloid-beta is one of the crucial factors for the onset and progression of Al...
关键词：nerve regeneration lipid rafts amyloid precursor protein autophagy LYSOSOME Alzhei-mer＇s disease Two-system Theory amyloid beta peptide AUTOPHAGOSOME National Financial MajorProject of China neural regeneration 
Motor recovery via aberrant pyramidal tract in a patient with traumatic brain injury A diffusion tensor tractography study被引量：1
《Neural Regeneration Research》2013年第1期90-94,共5页Sang Seok Yeo Sung Ho Jang 
supported by Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Education,Science and Technology,No.2012R1A1A4A01001873
The aberrant pyramidal tract is the collateral pathway of the pyramidal tract through the medial lemniscus in the brainstem. A 21-year-old man presented with right hemiparesis due to a traumatic intracerebral hemorrha...
关键词：neural regeneration neuroimaging diffusion tensor imaging diffusion tensor tractography transcranial magnetic stimulation pyramidal tract aberrant pyramidal tract motor paralysis motorrecovery traumatic brain injury head trauma intracerebral hemorrhage grant-supported paper photographs-containing paper NEUROREGENERATION 
Motor recovery via aberrant pyramidal tract in a patient with a cerebral peduncle infarct被引量：1
《Neural Regeneration Research》2011年第13期1023-1026,共4页Sang Seok Yeo Sung Ho Jang 
a grant from Daegu Metropolitan City R&D Project
The presence of the aberrant pyramidal tract has been demonstrated by several studies; however, little is known about its role in motor recovery in stroke patients. In the present study, we reported a 69-year-old righ...
关键词：diffusion tensor imaging aberrant pyramidal tract HEMIPARESIS motor recovery cerebral infarct  cerebral peduncle 
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