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LIPIDS: 作品数：396被引量：1047H指数：14; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：曹文斌黄正明陈鸿艳杨新波王晓峰更多>>; 相关机构：北京大学中国人民解放军北京军医学院江苏省人民医院华北科技学院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划北京市自然科学基金国家高技术研究发展计划更多>>

Imaging mass spectrometry:a molecular microscope for studying the role of lipids in Parkinson's disease: 《Neural Regeneration Research》2024年第6期1179-1180,共2页Vinata Vedam-Mai Jacob M.Samuel Boone M.Prentice; Parkinson's disease–A lipidopathy?The histopathological hallmark of Parkinson's disease(PD)and dementia with Lewy bodies are inclusions enriched inα-synuclein(α-syn),known as Lewy bodies,which are not only composed...; 关键词：LIPIDS SPECIES FOLDING

Multifunctional glycolipids as multi-targeting therapeutics for neural regeneration: 《Neural Regeneration Research》2024年第4期707-708,共2页Yutaka Itokazu; supported by a National Institute of Neurological Disorders and Stroke grant(R01 NS100839);a Sheffield Memorial Grant of the CSRA Parkinson’s Disease Support Group,and the excellent infrastructural support of the Department of Neuroscience and Regenerative Medicine,Medical College of Georgia at Augusta University(all to YI).; Many patients with neurodegenerative diseases,such as Alzheimer’s(AD)and Parkinson’s(PD)diseases suffer from disease progression without any satisfying clinical intervention,likely due to our lack of knowledge on ho...; 关键词：LIPIDS INVOLVEMENT diseases

Role of lipids in the control of autophagy and primary cilium signaling in neurons被引量：1: 《Neural Regeneration Research》2024年第2期264-271,共8页María Paz Hernández-Cáceres Daniela Pinto-Nuñez Patricia Rivera Paulina Burgos Francisco Díaz-Castro Alfredo Criollo Maria Jose Yañez Eugenia Morselli; funded by grants from Fondo Nacional de Desarrollo Científico y Tecnológico,FONDECYT 1200499 to EM,11200592 to MJY,1211329 to AC;by the ANID PIA ACT172066 to EM and AC;by the ANID postdoctoral fellowship 3210630 to MPHC;by the ANID doctoral fellowship 21230122 to DPN;by the ANID doctoral fellowship 21211189 to PR;by the ANID doctoral fellowship by the ANID doctoral fellowship 21210611 to FDC。; The brain is,after the adipose tissue,the organ with the greatest amount of lipids and diversity in their composition in the human body.In neurons,lipids are involved in signaling pathways controlling autophagy,a lyso...; 关键词：autophagic flux CHOLESTEROL fatty acids GPCR lysosomal storage diseases NEURONS NPC1 PHOSPHOINOSITIDES primary cilium

Impact of apolipoprotein E isoforms on sporadic Alzheimer's disease:beyond the role of amyloid beta被引量：4: 《Neural Regeneration Research》2024年第1期80-83,共4页Madia Lozupone Francesco Panza; The impact of apolipoprotein E(ApoE)isoforms on sporadic Alzheimer's disease has long been studied;however,the influences of apolipoprotein E gene(APOE)on healthy and pathological human brains are not fully understood...; 关键词：Alzheimer's disease AMYLOID-BETA apolipoprotein E DEMENTIA glymphatic transport LIPIDS neuropsychiatric symptoms neurovascular unit tau protein

Focus on LPA signaling:a promising therapeutic target to foster regeneration in immune-mediated neuropathies: 《Neural Regeneration Research》2023年第12期2651-2652,共2页Fabian Szepanowski Mark Stettner; Lysophospholipids are metabolites of glycerophospholipids and sphingolipids that are commonly found as lipid constituents of cell membranes.In addition to their function as structural membrane components,certain membe...; 关键词：LIPIDS THERAPEUTIC FOCUS

Apolipoprotein A1,the neglected relative of Apolipoprotein E and its potential role in Alzheimer’s disease被引量：3: 《Neural Regeneration Research》2021年第11期2141-2148,共8页Kristina Endres; supported by grants from the MWWK,Germany(research consortium NeuroDegX)to KE.; Lipoproteins are multi-molecule assemblies with the primary function of transportation and processing of lipophilic substances within aqueous bodily fluids(blood,cerebrospinal fluid).Nevertheless,they also exert other...; 关键词：Aβ APOA1 CHOLESTEROL high-density lipoproteins LIPIDS LIPOPROTEIN NEURODEGENERATION senile plaque

Microglia-oligodendrocyte intercellular communication: role of extracellular vesicle lipids in functional signalling被引量：4: 《Neural Regeneration Research》2021年第6期1194-1195,共2页Alice Gualerzi Marta Lombardi Claudia Verderio; supported by Italian Multiple Sclerosis Foundation(FISM)/2018/R/22(to CV).; The term microglia refers to the group of resident brain immune-cells that are responsible,mainly,for the immune response and the homeostasis of the brain.Unlike monocyte-derived macrophages that infiltrate the brain,...; 关键词：al. HOMEOSTASIS diseases

A role for lipids as agents to alleviate stroke damage： the neuroprotective effect of 2-hydroxy arachidonic acid: 《Neural Regeneration Research》2017年第8期1273-1275,共3页Irene F.Ugidos Diego Pérez-Rodríguez Arsenio Fernández-López; Cerebrovascular accident（CVA）or stroke is one of the world＇s leading causes of death and permanent disability.The high social and medical costs associated with this pathology mean there is an urgent need to find ef...; 关键词：the neuroprotective effect of 2-hydroxy arachidonic acid FFA OAA A role for lipids as agents to alleviate stroke damage MCAO

Neuroprotective properties of extracellular vesicles derived from mesenchymal stem cells被引量：1: 《Neural Regeneration Research》2016年第6期904-905,共2页akvile jarmalaviciūte augustas pivoriūnas; supported by National Research Programme,“Healthy ageing”(Grant No.SEN-15090)from Research Council of Lithuania; Extracellular vesicles（EVs）provide a novel mechanism of intercellular communication via the transfer of proteins,lipids,and miR NAs between cells.It is now widely accepted that cargo content of EVs depends on cell t...; 关键词：vesicles cargo intercellular physiological lipids comparable themselves notion neuronal displayed

Neuroprotective effects of monosialotetrahexosylganglioside被引量：2: 《Neural Regeneration Research》2015年第8期1343-1344,共2页Ai-ping Xi Zhong-xin Xu Feng-li Liu Yan-li Xu; supported by the National Natural Science Foundation of China(General Program),No.81373095; Monosialotetrahexosylganglioside（GM1）is a type of glycosphingolipid containing sialic acid that is closely related to cell-cell recognition,adhesion and signal conduction.GM1is mainly composed of ceramide and oligos...; 关键词：conduction chains injured neuronal backbone exogenous intercellular lipids registered peroxidation

LIPIDS