METFORMIN

作品数：365被引量：985H指数：15
导出分析报告
相关作者：甘玲陈代文韩伟潘卫三聂淑芳更多>>
相关机构：四川农业大学南京大学南方医科大学广东医科大学更多>>
相关期刊：更多>>
相关基金：国家自然科学基金中国博士后科学基金国家重点基础研究发展计划广东省自然科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
选择条件：
  • 期刊=Neural Regeneration Researchx
共 条 记 录，以下是1-9
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Autophagy-targeting modulation to promote peripheral nerve regeneration
《Neural Regeneration Research》2025年第7期1864-1882,共19页Yan Chen Hongxia Deng Nannan Zhang 
supported by the National Natural Science Foundation of China,Nos.82271411(to RG),51803072(to WLiu);grants from the Department of Finance of Jilin Province,Nos.2022SCZ25(to RG),2022SCZ10(to WLiu),2021SCZ07(to RG);Jilin Provincial Science and Technology Program,No.YDZJ202201ZYTS038(to WLiu);The Youth Support Programmed Project of China-Japan Union Hospital of Jilin University,No.2022qnpy11(to WLuo);The Project of China-Japan Union Hospital of Jilin University,No.XHQMX20233(to RG)。
Nerve regeneration following traumatic peripheral nerve injuries and neuropathies is a complex process modulated by diverse factors and intricate molecular mechanisms.Past studies have focused on factors that stimulat...
关键词：AUTOPHAGY autophagy related genes Charcot–Marie–Tooth diseases diabetic peripheral neuropathy METFORMIN MYELINATION peripheral nerve injury Schwann cells sciatic nerve Wallerian degeneration 
Metformin alleviates spinal cord injury by inhibiting nerve cell ferroptosis through upregulation of heme oxygenase-1 expression被引量：2
《Neural Regeneration Research》2024年第9期2041-2049,共9页Zhihua Wang Wu Zhou Zhixiong Zhang Lulu Zhang Meihua Li 
Previous studies have reported upregulation of heme oxygenase-1 in different central nervous system injury models.Heme oxygenase-1 plays a critical anti-inflammatory role and is essential for regulating cellular redox...
关键词：acyl-CoA synthetase long-chain family member 4 ferroptosis glutathione peroxidase 4 heme oxygenase-1 inflammation iron lipid peroxidation METFORMIN NEUROPROTECTION spinal cord injury 
Promising use of metformin in treating neurological disorders:biomarker-guided therapies被引量：2
《Neural Regeneration Research》2024年第5期1045-1055,共11页Allison Loan Charvi Syal Margarita Lui Ling He Jing Wang 
Neurological disorders are a diverse group of conditions that affect the nervous system and include neurodegenerative diseases(Alzheimer’s disease,multiple sclerosis,Parkinson’s disease,Huntington’s disease),cerebr...
关键词：Alzheimer’s disease Huntington’s disease METFORMIN mitochondrial perturbation multiple sclerosis neural degenerative diseases Parkinson’s disease stroke targeted therapy 
Metformin promotes angiogenesis and functional recovery in aged mice after spinal cord injury by adenosine monophosphate-activated protein kinase/endothelial nitric oxide synthase pathway被引量：4
《Neural Regeneration Research》2023年第7期1553-1562,共10页Jin-Yun Zhao Xiao-Long Sheng Cheng-Jun Li Tian Qin Run-Dong He Guo-Yu Dai Yong Cao Hong-Bin Lu Chun-Yue Duan Jian-Zhong Hu 
supported by the Natural Nature Science Foundation of China,Nos.82030071,81874004;the Science and Technology Major Project of Changsha,No.kh2103008(all to JZH).
Treatment with metformin can lead to the recovery of pleiotropic biological activities after spinal cord injury.However,its effect on spinal cord injury in aged mice remains unclear.Considering the essential role of a...
关键词：adenosine monophosphate-activated protein kinase/endothelial nitric oxide synthase pathway ANGIOGENESIS aged mice compound C METFORMIN spinal cord injury 
Promise of metformin for preventing age-related cognitive dysfunction被引量：1
《Neural Regeneration Research》2022年第3期503-507,共5页Leelavathi N.Madhu Maheedhar Kodali Ashok K.Shetty 
supported by grants from the National Institutes of Health (No.1R01NS106907,to AKS);the Department of Defense (Nos.W81XWH-17-1-0447 and W81XWH-19-1-0548,to AKS)。
The expanded lifespan of people,while a positive advance,has also amplified the prevalence of age-related disorders,which include mild cognitive impairment,dementia,and Alzheimer's disease.Therefore,competent therapie...
关键词：activated microglia aging AUTOPHAGY cognitive dysfunction memory METFORMIN mTOR signaling NEUROINFLAMMATION 
Research advances on how metformin improves memory impairment in “chemobrain”被引量：2
《Neural Regeneration Research》2022年第1期15-19,共5页Ahmad Alhowail Sridevi Chigurupati 
This work was supported by the Deanship of Scientific Research,Qassim University。
Cognitive impairment caused by chemotherapy,referred to as“chemobrain,”is observed in approximately 70% of cancer survivors.However,it is not completely understood how chemotherapy induces cognitive dysfunction,and ...
关键词：behavioral task chemobrain CHEMOTHERAPY cognitive impairments INFLAMMATION memory impairment METFORMIN neuroprotective agent review 
Low-dose metformin treatment in the subacute phase improves the locomotor function of a mouse model of spinal cord injury被引量：13
《Neural Regeneration Research》2021年第11期2234-2242,共9页Wen-Ye Song Han Ding Tiffany Dunn Jun-Ling Gao Javier Allende Labastida Caitlin Schlagal Guang-Zhi Ning Shi-Qing Feng Ping Wu 
supported by a grant from The Institute for Rehabilitation and Research Foundation,No.MC018-112(to PW);John S.Dunn Foundation,No.18168(to PW);the National Natural Science foundation of China,Nos.81620108018(to SQF),81930070(to SQF),82072439(to GZN);Tianjin Key Research and Development Plan,Key Projects For Science and Technology Support of China,No.19YFZCSY00660(to SQF);the National Key R&D Program of China,No.2019YFA0112100(to SQF).
Metformin,a first-line drug for type-2 diabetes,has been shown to improve locomotor recovery after spinal cord injury.However,there are studies reporting no beneficial effect.Recently,we found that high dose of metfor...
关键词：inflammation locomotor function METFORMIN MICROGLIA mortality NEUROPROTECTION spinal cord injury subacute administration 
Involvement of insulin receptor substrates in cognitive impairment and Alzheimer’s disease被引量：8
《Neural Regeneration Research》2019年第8期1330-1334,共5页Daisuke Tanokashira Wataru Fukuokaya Akiko Taguchi 
supported by a MEXTGrant-in-Aid for Scientific Research on Innovative Areas(brain environment)(JP24111536; to AT);JSPS KAKENHI(JP24650201,JP26282026,JP17K19951,JP17H02188; to AT);grants from the Mitsubishi Foundation(to AT);NOVARTIS Foundation Japan for the Promotion of Science(to AT)
Type 2 diabetes一associated with impaired insulin/insulin-like growth factor-1 (IGF1) signaling (IIS)一is a risk factor for cognitive impairment and dementia including Alzheimer's disease (AD). The insulin receptor su...
关键词：type 2 diabetes insulin/insulin^like growth factor-1 INSULIN receptor substrate Alzheimer's disease aging SERINE phosphorylation METFORMIN NEUROPROTECTIVE effects high-fat-diet 
Metformin inhibits food intake and neuropeptide Y gene expression in the hypothalamus被引量：2
《Neural Regeneration Research》2013年第25期2379-2388,共10页Yale Duan Rui Zhang Min Zhang Lijuan Sun Suzhen Dong Gang Wang Jun Zhang Zheng Zhao 
supported by grants from the National Natural Science Foundation of China,No.31171019 and No.31200820;the Opening Project of Shanghai Key Laboratory of Brain Functional Genomics and Key Laboratory of Brain Functional Genomics(East China Normal University)of the Ministry of Education
Metformin may reduce food intake and body weight, but the anorexigenic effects of metformin are still poorly understood. In this study, Sprague-Dawley rats were administered a single intracere- broventricular dose of ...
关键词：neural regeneration METFORMIN food intake body weight gain HYPOTHALAMUS AMP-activated pro-tein kinase neuropeptide Y grants-supported paper NEUROREGENERATION 
全选清除导出
共1页<1>
检索报告 对象比较 聚类工具 使用帮助 返回顶部