OSTEOPOROTIC

作品数：76被引量：346H指数：11
导出分析报告
相关领域：医药卫生更多>>
相关作者：吴子祥张波李建磊韩维奇蒋伟宇更多>>
相关机构：南方医科大学第三附属医院温州医科大学泗洪县人民医院成都军区总医院更多>>
相关期刊：更多>>
相关基金：国家自然科学基金中国博士后科学基金国家重点基础研究发展计划重庆市自然科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
选择条件：
  • 期刊=Bioactive Materialsx
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Augmenting osteoporotic bone regeneration through a hydrogel-based rejuvenating microenvironment
《Bioactive Materials》2024年第11期440-454,共15页Xiaoting Zhang Boguang Yang Lu Feng Xiayi Xu Chenmin Wang Yuk-wai Lee Ming Wang Xuan Lu Ling Qin Sien Lin Liming Bian Gang Li 
National Natural Science Foundation of China(82172430 and 82272505);University Grants Committee,Research Grants Council of the Hong Kong Special Administrative Region,China(14113723,14108720,14121721,14202920,N_CUHK472/22,C7030-18G,T13-402/17-N and AoE/M-402/20);Heath and Medical Research Fund(HMRF)Hong Kong(17180831,08190416 and 09203436);Hong Kong Innovation Technology Commission Funds(PRP/050/19FX),CUHK direct grant(2022.042).
Osteoporotic bone defects pose a significant challenge for bone regeneration as they exhibit impaired healing capacity and delayed healing period.To address this issue,this study introduces a hydrogel that creates a r...
关键词：Osteoporotic bone defects Bone regeneration Rejuvenating microenvironment SECRETOME Focal adhesion pathway 
Biodegradable Zn-2Cu-0.5Zr alloy promotes the bone repair of senile osteoporotic fractures via the immune-modulation of macrophages
《Bioactive Materials》2024年第8期422-437,共16页Huanzhong Ji Gang Shen Hanghang Liu Yao Liu Junyu Qian GuoJiang Wan En Luo 
supported by Grants from the National Natural Science Foundation of China(82370932);Research and Develop Program,West China Hospital of Stomatology Sichuan University(RD-03-202102);Program of Science and Technology Department of Sichuan Province(2023ZYD0107).The authors declare no potential conflicts of interest with respect to the authorship and/or publication of this article.
Delayed bone-healing of senile osteoporotic fractures remains a clinical challenge due to the alterations caused by aging in bone and immune systems.The novel biomaterials that address the deficiencies in both skeleta...
关键词：Zinc-based biodegradable metals Macrophage Bone regeneration Immune-osteo microenvironment Senile osteoporotic bone fracture healing 
A biomimetic and bioactive scaffold with intelligently pulsatile teriparatide delivery for local and systemic osteoporosis regeneration被引量：8
《Bioactive Materials》2023年第1期75-87,共13页Lingbin Che Ying Wang Dongyong Sha Guangyi Li Ziheng Wei Changsheng Liu Yuan Yuan Dianwen Song 
supported by National Natural Science Foundation of China for Innovative Research Groups(No.51621002);Frontiers Science Center for Materiobiology and Dynamic Chemistry(No.JKVD1211002);National Natural Science Foundation of China(Nos.81571828,31771040,31971264).
Osteoporosis is one of the most disabling consequences of aging,osteoporotic fractures and higher risk of the subsequent fractures leading to substantial disability and deaths,indicating both local fractures healing a...
关键词：Precise pulsatile release TERIPARATIDE Smart delivery Osteoporotic bone regeneration 
Reversing the imbalance in bone homeostasis via sustained release of SIRT-1 agonist to promote bone healing under osteoporotic condition被引量：5
《Bioactive Materials》2023年第1期429-443,共15页Wei Zhang Xingzhi Zhou Weiduo Hou Erman Chen Chenyi Ye Mo Chen Qian Lu Xiaohua Yu Weixu Li 
supported by a grant from the National Natural Science Foundation of China(No.81802221,31870959,82102597);Zhejiang Provincial Natural Science Foundation of China(LY21H070001,LQ21H060007,LY22H060006);Zhejiang Undergraduate Talent Project(No.2021R401214).
The imbalance of bone homeostasis is the root cause of osteoporosis.However current therapeutic approaches mainly focus on either anabolic or catabolic pathways,which often fail to turn the imbalanced bone metabolism ...
关键词：Osteoporosis OSTEOBLAST OSTEOCLAST Mineral coating SIRT1 
Osteoporotic bone recovery by a bamboo-structured bioceramic with controlled release of hydroxyapatite nanoparticles被引量：6
《Bioactive Materials》2022年第11期379-393,共15页Rui Zhao Tieliang Shang Bo Yuan Xiangdong Zhu Xingdong Zhang Xiao Yang 
This project was funded by National Natural Science Foundation of China(grant no.81971755);Sichuan Science and Technology Program(2020YFS0038);Fundamental Research Funds for the Central Uni-versities.We thank Dr.Li Chen from the Analytical&Testing Center of Sichuan University for assistance with micro-CT images.
While most bone defects can be repaired spontaneously,the healing process can be complicated due to insuf-ficient bone regeneration when osteoporosis occurs.Synthetic materials that intrinsically stimulate bone for-ma...
关键词：Nano hydroxyapatite BIOCERAMICS OSTEOGENESIS Bone regeneration OSTEOPOROSIS 
A programmed surface on polyetheretherketone for sequentially dictating osteoimmunomodulation and bone regeneration to achieve ameliorative osseointegration under osteoporotic conditions被引量：4
《Bioactive Materials》2022年第8期364-376,共13页Yanyan Zheng Ang Gao Jiaxiang Bai Qing Liao Yuzheng Wu Wei Zhang Min Guan Liping Tong Dechun Geng Xin Zhao Paul K.Chu Huaiyu Wang 
financial support from the National Natural Science Foundation of China(Nos.31922040 and 82001965);Shenzhen Science and Technology Research Funding(Nos.SGLH20180625144002074,JCYJ20180507182637685,and JCYJ20190806165616542);Youth Innovation Promotion Association of Chinese Academy of Sciences(Nos.2017416 and 2020353);Guangdong Basic and Applied Basic Research Foundation(No.2020B1515120078);China Postdoctoral Science Foundation(2019M663190);SIAT Innovation Program for Excellent Young Researchers(E1G034);Nanchong Science and Technology Project(No.20SXQT0302);City University of Hong Kong Strategic Research Grant(SRG)(No.7005505).
Polyetheretherketone(PEEK)is a desirable alternative to conventional biomedical metals for orthopedic implants due to the excellent mechanical properties.However,the inherent bioinertness of PEEK contributes to inferi...
关键词：POLYETHERETHERKETONE Surface modification Osteoimmunomodulation Sequential release OSTEOPOROSIS OSSEOINTEGRATION 
Mn-containing bioceramics inhibit osteoclastogenesis and promote osteoporotic bone regeneration via scavenging ROS被引量：15
《Bioactive Materials》2021年第11期3839-3850,共12页Jianmei Li Cuijun Deng Wanyuan Liang Fei Kang Yun Bai Bing Ma Chengtie Wu Shiwu Dong 
the Key Program of National Natural Science Foundation of China(81930067);the Youth Program of National Natural Science Foundation of China(grant number 82002316);the Youth Cultivation Project of Army Medical University(2020XQN08);General Program of Natural Science Foundation of Chongqing(cstc2019jcyj-msxmX0176).
Osteoporosis is caused by an osteoclast activation mechanism.People suffering from osteoporosis are prone to bone defects.Increasing evidence indicates that scavenging reactive oxygen species(ROS)can inhibit receptor ...
关键词：Mn-containing bioceramics Antioxidant biomaterials OSTEOCLASTOGENESIS ROS Osteoporotic bone regeneration 
Lithium chloride promotes osteogenesis and suppresses apoptosis during orthodontic tooth movement in osteoporotic model via regulating autophagy被引量：10
《Bioactive Materials》2021年第10期3074-3084,共11页Li Huang Xing Yin Jun Chen Ruojing Liu Xiaoyue Xiao Zhiai Hu Yan He Shujuan Zou 
This work was supported by National Natural Science Foundation of China(Grants No.81801019,81701032,82071150);National Key Research and Development Program of China(Grant No.2018YFC1105703).
Osteoporosis is a widely distributed disease that may cause complications such as accelerated tooth movement,bone resorption,and tooth loss during orthodontic treatment.Promoting bone formation and reducing bone resor...
关键词：Lithium chloride AUTOPHAGY OSTEOGENESIS Orthodontic tooth movement APOPTOSIS 
Synergistic anti-inflammatory and osteogenic n-HA/resveratrol/chitosan composite microspheres for osteoporotic bone regeneration被引量：13
《Bioactive Materials》2021年第5期1255-1266,共12页Limei Li Mali Yu Yao Li Qing Li Hongcai Yang Meng Zheng Yi Han Di Lu Sheng Lu Li Gui 
supported by the National Natural Science Foundation of China(81460173/81860326/81960268);the Department of Science and Technology of Yunnan Province of China(2017FF117(-062)/2018FE001(-137)/2018FE001(-125)/2019ZF011-2).
The development of functional materials for osteoporosis is ultimately required for bone remodeling.However,grafts were accompanied by increasing pro-inflammatory cytokines that impaired bone formation.In this work,na...
关键词：n-HA/Res/CS microsphere ANTI-INFLAMMATION Osteo-differentiation Osteoporotic bone regeneration 
Nano-needle strontium-substituted apatite coating enhances osteoporotic osseointegration through promoting osteogenesis and inhibiting osteoclastogenesis被引量：8
《Bioactive Materials》2021年第4期905-915,共11页Zhen Geng Luli Ji Zhaoyang Li Jing Wang Hongyan He Zhenduo Cui Xianjin Yang Changsheng Liu 
the National Natural Science Foundation of China for Innovative Research Groups(Grant No.51621002);China Postdoctoral Science Foundation(Grant No.2018M640350);National Natural Science Foundation of China(Grant No.51871163);Shanghai International S&T Cooperation Project(Grant No.18520710100).
Implant loosening remains a major clinical challenge for osteoporotic patients.This is because osteoclastic bone resorption rate is higher than osteoblastic bone formation rate in the case of osteoporosis,which result...
关键词：Calcium STRONTIUM Mineralization Osteoclast activity OSSEOINTEGRATION 
全选清除导出
共2页<12>
检索报告 对象比较 聚类工具 使用帮助 返回顶部