ADENYLATE

作品数:21被引量:31H指数:4
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相关领域:医药卫生生物学更多>>
相关作者:陈颖梅岩艾更多>>
相关机构:复旦大学中国药科大学更多>>
相关期刊:《Asian pacific Journal of Reproduction》《Chinese Medicine》《Neural Regeneration Research》《Acta Biochimica et Biophysica Sinica》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划广东省自然科学基金更多>>
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Endoplasmic reticulum adenylate transporter activity affects amino acid metabolism under photorespiratory conditions
《The Crop Journal》2024年第6期1633-1644,共12页Jieni Li Yuxin Song Xin Luan Yajun Gou Tao Xie Yu Hong Na Liu Yao Su Xueli Fu Tianxiu Zhong Shu Chen Yuexiong Zhang Gang Qin Xiang-Qian Zhang 
supported by the National Natural Science Foundation of China (31671594);Guangdong Basic and Applied Basic Research Foundation (2024A1515011098,2021A1515012482).
The involvement of the endoplasmic reticulum(ER)-localized adenylate transporter1(ER-ANT1)in photorespiratory metabolism has been established,yet its precise physiological function remains uncertain.Rice er-ant1 mutan...
关键词:Endoplasmic reticulum PHOTORESPIRATION Amino acid Glutamate/alanine aminotransferase ER-ANT1 
New N-acylated aminoalkanoic acids from tea roots derived biocontrol agent Clonostachys rosea 15020
《Synthetic and Systems Biotechnology》2024年第4期684-693,共10页Jiaming Yu Yue Zhang Li Zhang Jie Shi Kun Wang Weize Yuan Zexu Lin Shangqian Ning Bohao Wang Xinye Wang Yuyang Qiu Tom Hsiang Lixin Zhang Xueting Liu Guoliang Zhu 
support from the National Key Research and Development Program of China(2019YFA0906200);the National Natural Science Foundation of China(21977029,81903529,21877038,31720103901,and 81573341);the Open Project Funding of the State Key Laboratory of Bioreactor Engineering,the 111 Project(B18022).
Four new N-acylated aminoalkanoic acids,namely clonoroseins E−H(1−4),together with three previously identified analogs,clonoroseins A,B,and D(5−7),were identified from the endophytic fungus Clonostachys rosea strain 1...
关键词:Endophytic fungi N-acylated aminoalkanoic acid FBMN Adenylate-forming enzyme 
A Preliminary Study in the Effect of <i>Astragali radix</i>, a Qi-Invigorating Herb, on Mitochondria: Insights at Cellular Level and Mouse Tissues Level
《Chinese Medicine》2020年第3期113-125,共13页Yu Chen Mengmei Li Zhongzhen Cai Yuming Chen Lin Wang Jie Teng Qian Feng Caixia Li Glen Rein Bruce Qing Tang Xuemei Bai 
Objectives: To explore the effects of Qi-invigorating herbs on mitochondrial function using cultured cells and animal organs. ...
关键词:QI Astragali radix MITOCHONDRIA Total Adenylate Antioxidant Capacity 
Stress granules in colorectal cancer:Current knowledge and potential therapeutic applications被引量:5
《World Journal of Gastroenterology》2020年第35期5223-5247,共25页Noémie Legrand Dan A Dixon Cyril Sobolewski 
Supported by Geneva Cancer League,No.1711;National Institutes of Health,No.R01 CA243445;and National Cancer Institute Cancer Center Support Grant,No.P30 CA168524.
Stress granules(SGs)represent important non-membrane cytoplasmic compartments,involved in cellular adaptation to various stressful conditions(e.g.,hypoxia,nutrient deprivation,oxidative stress).These granules contain ...
关键词:Stress-Granules Colorectal cancer Adenylate-Uridylate-rich element-binding proteins Post-transcriptional regulation ONCOGENES Tumor suppressors 
Adenylate cyclase activator forskolin alleviates intracerebroventricular propionic acid-induced mitochondrial dysfunction of autistic rats被引量:1
《Neural Regeneration Research》2020年第6期1140-1149,共10页Sidharth Mehan Saloni Rahi Aarti Tiwari Tarun Kapoor Kajal Rajdev Ramit Sharma Himanshi Khera Sourabh Kosey Umesh Kukkar Rajesh Dudi 
Neuronal mitochondrial dysfunction increases inflammatory mediators and leads to free radical generation and anti-oxidant enzymatic alterations,which are major neuropathological hallmarks responsible for autism.Mitoch...
关键词:ADENYLATE CYCLASE ATP AUTISM FORSKOLIN mitochondrial dysfunction neuroinflammation oxidative stress propionic acid 
The allosteric modulation effects of doxycycline, minocycline, and their derivatives on the neuropeptide receptor PAC1-R被引量:2
《Acta Biochimica et Biophysica Sinica》2019年第6期627-637,共11页Suqin Song Like Wang Junfeng Li Xiaoling Huang Rongjie Yu 
This work was supported by the grants from the National Natural Science Foundation of China (Nos.31100545 and 31670848);the Natural Science Foundation of Guangdong Province (No.2016A030313087).
Class B G-protein coupled receptors (GPCR) PAC1-R is a neuropeptide pituitary adenylate cyclase activating polypeptide(PACAP)-preferring receptor that mediates the effective neuroprotective activity.Based on our previ...
关键词:pituitary ADENYLATE cyclase-activating polypeptide G-PROTEIN coupled RECEPTOR PAC1-R allosteric modulator DOXYCYCLINE MINOCYCLINE N-terminal extra cellular domain 
AU-rich element-binding proteins in colorectal cancer被引量:9
《World Journal of Gastrointestinal Oncology》2019年第2期71-90,共20页Noémie Legrand Dan A Dixon Cyril Sobolewski 
Supported by the National Institutes of Health/National Cancer Institute Cancer Center Support grant P30 CA168524(DD);supported by a grant of the Geneva Cancer League(Grant no.1711)
Trans-acting factors controlling mRNA fate are critical for the post-transcriptional regulation of inflammation-related genes, as well as for oncogene and tumor suppressor expression in human cancers. Among them, a gr...
关键词:COLORECTAL cancer Adenylate-Uridylate-rich element-binding proteins ONCOGENES Tumor SUPPRESSORS POST-TRANSCRIPTIONAL regulation 
Genetic polymorphism and natural fertility in women
《Asian pacific Journal of Reproduction》2018年第1期19-21,共3页Fulvia Gloria-Bottini Neri A Pietropolli A Magrini A Bottini E 
Objective: To investigate the cooperative interaction among five genetic systems (phosphoglucomutase locus 1, adenosine deaminase locus 1, acid phosphatase locus 1, adenylate kinase locus 1, and haptoglobin) concernin...
关键词:WOMEN FERTILITY Genetic polymorphism Phosphoglucomutase LOCUS 1 Adenosine DEAMINASE LOCUS 1 Acid phosphatase LOCUS 1 ADENYLATE kinase LOCUS 1 HAPTOGLOBIN 
Potential PET Ligands for Imaging of Cerebral VPAC and PAC Receptors: Are Non-Peptide Small Molecules Superior to Peptide Compounds?被引量:1
《World Journal of Neuroscience》2015年第5期364-384,共21页Margit Pissarek 
Pituitary adenylate cyclase activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP) have been known for decades to mediate neuroendocrine and vasodilative actions via G-protein-coupled receptors of Clas...
关键词:Class B RECEPTORS Vasoactive Intestinal PEPTIDE Pituitary ADENYLATE Cyclase Activating Polypeptide NON-PEPTIDE LIGANDS PET SPECT 
Determining relaxin-3/RXFP3 activation by inhibition of forskolin induced cAMP assay
《中国药理学与毒理学杂志》2015年第S1期22-23,共2页JayakodyJPT HerrDR DaweGS 
The project supported by the Biomedical Research Council of Singapore(BMRC 10/1/21/19/645);National Medical Research Council of Singapore(NMRC/1287/2011);the Ministry of Education,Singapore,Academic Research Fund Tier 1Seed Fund for Basic Science Research(T1-BSRG 2014-03)
OBJECTIVE Relaxin-3 is a novel neuropeptide of the relaxin insulin family of peptides.So far,many studies have reported the role of relaxin-3/RXFP3 system in regulating feeding,stress response and cognition.In previou...
关键词:NEUROPEPTIDE relaxin-3 ADENYLATE cyclise FORSKOLIN