supported by the National Natural Science Foundation of China (31671594);Guangdong Basic and Applied Basic Research Foundation (2024A1515011098,2021A1515012482).
The involvement of the endoplasmic reticulum(ER)-localized adenylate transporter1(ER-ANT1)in photorespiratory metabolism has been established,yet its precise physiological function remains uncertain.Rice er-ant1 mutan...
support from the National Key Research and Development Program of China(2019YFA0906200);the National Natural Science Foundation of China(21977029,81903529,21877038,31720103901,and 81573341);the Open Project Funding of the State Key Laboratory of Bioreactor Engineering,the 111 Project(B18022).
Four new N-acylated aminoalkanoic acids,namely clonoroseins E−H(1−4),together with three previously identified analogs,clonoroseins A,B,and D(5−7),were identified from the endophytic fungus Clonostachys rosea strain 1...
Supported by Geneva Cancer League,No.1711;National Institutes of Health,No.R01 CA243445;and National Cancer Institute Cancer Center Support Grant,No.P30 CA168524.
Stress granules(SGs)represent important non-membrane cytoplasmic compartments,involved in cellular adaptation to various stressful conditions(e.g.,hypoxia,nutrient deprivation,oxidative stress).These granules contain ...
Neuronal mitochondrial dysfunction increases inflammatory mediators and leads to free radical generation and anti-oxidant enzymatic alterations,which are major neuropathological hallmarks responsible for autism.Mitoch...
This work was supported by the grants from the National Natural Science Foundation of China (Nos.31100545 and 31670848);the Natural Science Foundation of Guangdong Province (No.2016A030313087).
Class B G-protein coupled receptors (GPCR) PAC1-R is a neuropeptide pituitary adenylate cyclase activating polypeptide(PACAP)-preferring receptor that mediates the effective neuroprotective activity.Based on our previ...
Supported by the National Institutes of Health/National Cancer Institute Cancer Center Support grant P30 CA168524(DD);supported by a grant of the Geneva Cancer League(Grant no.1711)
Trans-acting factors controlling mRNA fate are critical for the post-transcriptional regulation of inflammation-related genes, as well as for oncogene and tumor suppressor expression in human cancers. Among them, a gr...
Objective: To investigate the cooperative interaction among five genetic systems (phosphoglucomutase locus 1, adenosine deaminase locus 1, acid phosphatase locus 1, adenylate kinase locus 1, and haptoglobin) concernin...
Pituitary adenylate cyclase activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP) have been known for decades to mediate neuroendocrine and vasodilative actions via G-protein-coupled receptors of Clas...
The project supported by the Biomedical Research Council of Singapore(BMRC 10/1/21/19/645);National Medical Research Council of Singapore(NMRC/1287/2011);the Ministry of Education,Singapore,Academic Research Fund Tier 1Seed Fund for Basic Science Research(T1-BSRG 2014-03)
OBJECTIVE Relaxin-3 is a novel neuropeptide of the relaxin insulin family of peptides.So far,many studies have reported the role of relaxin-3/RXFP3 system in regulating feeding,stress response and cognition.In previou...