PROTOONCOGENE

作品数：11被引量：36H指数：3
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相关领域：医药卫生生物学更多>>
相关作者：郝秀娟更多>>
相关机构：北京基础医学研究所更多>>
相关期刊：《中国现代普通外科进展》《Developmental and Reproductive Biology》《World Journal of Gastroenterology》《Chinese Medical Journal》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划更多>>
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Current concepts in ameloblastoma-targeted therapies in B-raf proto-oncogene serine/threonine kinase V600E mutation: Systematic review被引量：7
《World Journal of Clinical Oncology》2020年第1期31-42,共12页Rogelio González-González Sandra López-Verdín Jesús Lavalle-Carrasco Nelly Molina-Frechero Mario Isiordia-Espinoza Ramón G Carreón-Burciaga Ronell Bologna-Molina 
BACKGROUND Ameloblastomas are common benign epithelial odontogenic neoplasms that present an aggressive and unpredictable behavior that may modify treatment strategies.Different signaling pathways that participate in ...
关键词：AMELOBLASTOMA B-raf proto-oncogene serine/threonine kinase B-raf protooncogene serine/threonine kinase V600E Additional mutations Targeted therapies 
Astilbin Inhibits Proliferation of Rat Aortic Smooth Muscle Cells Induced by Angiotensin Ⅱ and Down-regulates Expression of Protooncogene被引量：1
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2012年第2期181-185,共5页李平 高思海 揭伟 敖启林 黄亚非 
supported by agrant from the National Natural Science Foundation of China(No.30500656)
This study examined the effect of astilbin on the proliferation of rat aortic smooth muscle cells (RASMCs) induced by angiotensin Ⅱ (AngⅡ) and explored the possible mechanisms. Cell proliferation model of RASMCs was...
关键词：ASTILBIN vascular smooth muscle cells PROLIFERATION angiotensin Ⅱ PROTOONCOGENE NF-κB 
Fra-1 protooncogene regulates IL-6 expression in macrophages and promotes the generation of M2d macrophages被引量：19
《Cell Research》2010年第6期701-712,共12页Qingshan Wang Hong Ni Lan Lan Xiaoli Wei Rong Xiang Yue Wang 
The tumor microenvironment （TME） plays a prominent role in the growth of tumor cells. As the major inflammatory component of the TME, M2d macrophages are educated by the TME such that they adopt an immunosnppressive...
关键词：Fra-1 M2d IL-6 generation PHENOTYPE CO-CULTURE 
A novel gain of function mutant in C-kit gene and its tumorigenesis in nude mice被引量：6
《World Journal of Gastroenterology》2005年第45期7104-7108,共5页Chen-Guang Bai Xiao-Hong Liu Qiang xie Fei Feng Da-Lie Ma 
Supported by the National Natural Science Foundation of China No. 30070743 and No. 30471702
AIM： To transfect mutant C-kit cDNA at codon 579 into human embryonic kidney cell line to observe its role in the pathogenesis of gastrointestinal stromal tumor （GIST）. METHODS： Eukaryotic expression vectors of pc...
关键词：Gastrointestinal stromal tumors ProtooncogeneC-kit Gene mutation Malignant transformation 
The effect of thyrotropin receptor antibodies on the proliferation of FRTL-5 cells and the expression of protooncogene c-fos mRNA
《Chinese Medical Journal》1998年第5期29-32,共4页方佩华 吕枚 周卫东 李建民 徐秉锐 汤特 谭郁彬 
Abstract Objective Hyperthyroidism and a diffuse goiter are the main symptoms of Graves' disease (GD) associated with autoantibodies to thyroid stimulating hormone (TSH) receptor (TRAb). The present study was...
Protooncogene c-fos overexpression in NADPH-d positive neurons of the amygdala in soman induced seizures in the rat
《Journal of Medical Colleges of PLA(China)》1998年第1期43-48,共6页景德强 陈尔瑜 余争平 程天民 
Fos immunohistochemistry and NADPH-d histochemistry and double labeling of the 2 methods were used to study therelationship between c-Fos expressed neurons and NADPH-d positive neurons of the amygdala in soman-induced...
关键词：C-FOS NITRIC oxide AMYGDALA SOMAN seilzure 
Somatic mutations in the RET protooncogene in Japanese and Chinese sporadic medullary thyroid carcinomas
《中国现代普通外科进展》1998年第1期54-57,共4页ShanLiang MisaNakamura YashiNakamura JingXuefeng ToyoharuYokoi KennichiKakudo ShouNanhai JiangXihongJian 
Objective Despite advances in the understanding of the genotype - phenotype correlation in multiple endocrine neoplasia type 2A and 2B (MEN 2A, MEN 2B), and familial medullary thyroid carcinoma (FMTC), the frequency a...
关键词：甲状腺髓样癌 分子生物学 基因突变 RET PROTOONCOGENE 
Developmental expression of c-kit protooncogene in the rat testis
《生殖医学杂志》1997年第S1期21-26,共6页贾孟春 周丽瀛 
In this study very pure type A spermatogonia, pachytene spermatocytes, round sper-matids and Sertoli cells from rat testis were successfully isolated. The expression of the c-kit receptor,a specific receptor for kit l...
关键词：C-KIT SPERMATOGONIA TESTIS RAT 
AgNOR and rasp21 expression in gastric mucosal lesions with Helicobacter pylori infection被引量：3
《World Journal of Gastroenterology》1997年第4期54-54,共1页GAO HengJun, LU XiuZhen, ZHANG XiaoYong and ZHAO ZhiQuanDepartment of Gastroenterology, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, Jiangsu Province, China  
IM To study the number of AgNOR and rasp21 expression in different gastric mucosal lesions with Helicobacter pylori (Hp) infection to evaluate their biological behaviour and possible mechanism of Hp. METHODS Hp (usi...
关键词：Helicobacter pylori/pathogenicity gastric mucosal/pathology STOMACH diseases/microbiology STOMACH neoplasms/microbiology nucleoproteins/metabolism PROTOONCOGENE protein P21/(RAS) 
INHIBITION OF C-MYC PROTEIN EXPRESSION AND CELL PROLIFERATION IN HL-60 CELLS BY ANTISENSE TRANSCRIPTS TO c-myc
《中国实验血液学杂志》1995年第4期370-375,共6页郝秀娟 
The human promyelocytic cell line HL-60 overexpresses the c-myc protooncogene. Plasmid pDACx carrying antisense human c-myc DNA and neo gene was introduced into HL-60 cells with lipofectin reagent. Upon DNA entering t...
关键词：C-MYC PROTOONCOGENE ANTISENSE TRANSCRIPT gene transfer 
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