云南高校图书馆联盟文献共享服务平台- OXIDATIVE

OXIDATIVE_STRESS: 作品数：1723被引量：7239H指数：30; 导出分析报告; 相关作者：张国兴袁红张韶峰刘平白丽敏更多>>; 相关机构：华中科技大学北京大学哈尔滨医科大学中国医学科学院北京协和医学院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>

Acquired sensorineural hearing loss,oxidative stress,and microRNAs: 《Neural Regeneration Research》2025年第9期2513-2519,共7页Desmond A.Nunez Ru C.Guo; Hearing loss is the third leading cause of human disability.Age-related hearing loss,one type of acquired sensorineural hearing loss,is largely responsible for this escalating global health burden.Noise-induced,ototox...; 关键词：hearing loss HYPOXIA MICRORNAS oxidative stress SENSORINEURAL

Hydrogen sulfide reduces oxidative stress in Huntington's disease via Nrf2: 《Neural Regeneration Research》2025年第6期1776-1788,共13页Zige Jiang Dexiang Liu Tingting Li Chengcheng Gai Danqing Xin Yijing Zhao Yan Song Yahong Cheng Tong Li Zhen Wang; supported by the National Natural Science Foundation of China,Nos.82271327 (to ZW),82072535 (to ZW),81873768 (to ZW),and 82001253 (to TL)。; The pathophysiology of Huntington's disease involves high levels of the neurotoxin quinolinic acid. Quinolinic acid accumulation results in oxidative stress, which leads to neurotoxicity. However, the molecular and ce...; 关键词：apoptosis CYSTATHIONINE-Β-SYNTHASE nuclear factor erythroid 2-related factor 2 Huntington's disease hydrogen sulfide MITOCHONDRION NEUROPLASTICITY oxidative stress quinolinic acid reactive oxygen species

Tranylcypromine upregulates Sestrin 2 expression to ameliorate NLRP3-related noise-induced hearing loss: 《Neural Regeneration Research》2025年第5期1483-1494,共12页Xihang Chen Zhifeng Chen Menghua Li Weiwei Guo Shuolong Yuan Liangwei Xu Chang Lin Xi Shi Wei Chen Shiming Yang; supported by the National Key Research and Development Program of China,No.2022YFC2402701(to WC);Key International(Regional)Joint Research Program of the National Natural Science Foundation of China,No.81820108009(to SY);the National Natural Science Foundation of China,Nos.81970890(to WC)and 82371148(to WG);Fujian Provincial Healthcare Young and Middle-aged Backbone Talent Training Project,No.2023GGA035(to XC);Spring City Plan;the High-level Talent Promotion and Training Project of Kunming,No.2022SCP001(to SY);the Natural Science Foundation of Hainan Province of China,No.824MS052(to XS);the Sixth Medical Center of Chinese PLA General Hospital Innovation Cultivation,No.CXPY202116(to LX)。; Noise-induced hearing loss is the primary non-genetic factor contributing to auditory dysfunction.However,there are currently no effective pharmacological interventions for patients with noise-induced hearing loss.Her...; 关键词：4-HYDROXYNONENAL apoptosis AUTOPHAGY cleaved caspase-3 inflammation NOD-like receptor family pyrin domain-containing 3(NLRP3) noise-induced hearing loss oxidative stress Sestrin2 TRANYLCYPROMINE

Potential role and therapeutic implications of glutathione peroxidase 4 in the treatment of Alzheimer's disease: 《Neural Regeneration Research》2025年第3期613-631,共19页Yanxin Shen Guimei Zhang Chunxiao Wei Panpan Zhao Yongchun Wang Mingxi Li Li Sun; supported by the National Natural Science Foundation of China,No.82071442 (to LS);a grant from the Jilin Provincial Department of Finance,No.JLSWSRCZX2021-004 (to LS)。; Alzheimer's disease is an age-related neurodegenerative disorder with a complex and incompletely understood pathogenesis. Despite extensive research, a cure for Alzheimer's disease has not yet been found. Oxidative st...; 关键词：apoptosis ferroptosis inflammation lipid peroxidation natural plant products neurodegenerative disorder NEUROPROTECTION oxidative stress small-molecule drugs

Lipid droplets in the nervous system:involvement in cell metabolic homeostasis: 《Neural Regeneration Research》2025年第3期740-750,共11页Yuchen Zhang Yiqing Chen Cheng Zhuang Jingxuan Qi Robert Chunhua Zhao Jiao Wang; funded by Basic Research Program of Shanghai,No.20JC1412200(to JW);the National Key Research and Development Program of China,No.2020YFA0113000(to RCZ)。; Lipid droplets serve as primary storage organelles for neutral lipids in neurons,glial cells,and other cells in the nervous system.Lipid droplet formation begins with the synthesis of neutral lipids in the endoplasmic...; 关键词：Alzheimer's disease lipid droplet biogenesis lipid droplets lipid metabolism nervous system neurodegenerative disorders oxidative stress Parkinson's disease

Vanillylacetone attenuates cadmium chloride-induced hippocampal damage and memory loss through upregulation of nuclear factor erythroid 2-related factor 2 gene and protein expression: 《Neural Regeneration Research》2024年第12期2750-2759,共10页Fahaid H.A.L-Hashem Salah O.Bashir Amal F.Dawood Moutasem S.Aboonq Ismaeel Bin-Jaliah Abdulaiziz M.Al-Garni Mohamed D.Morsy; funded by the Research Deanship of King Khalid University,No.GRP-215-43 (to FHA);Princess Nourah bint Abdulrohman University Researchers Supporting Project,No.PNURSP2023R110 (to AFD)。; Memory loss and dementia are major public health concerns with a substantial economic burden.Oxidative stress has been shown to play a crucial role in the pathophysiology of hippocampal damage-induced memory impairmen...; 关键词：HIPPOCAMPUS NEUROPROTECTIVE Nrf2 gene oxidative stress vanillylacetone

OSMR is a potential driver of inflammation in amyotrophic lateral sclerosis: 《Neural Regeneration Research》2024年第11期2513-2521,共9页Wenzhi Chen Shishi Jiang Shu Li Cheng Li Renshi Xu; supported by the National Natural Science Foundation of China,Nos.30560042,81160161,81360198,82160255;a grant from Department of Education of Jiangxi Province,Nos.GJJ13198,GJJ170021;Jiangxi Provincial Department of Science and Technology,Nos.[2014]-47,20142BBG70062,20171BAB215022,20192BAB205043;Science and Technology Plan of Jiangxi Commission of Health,Nos.202210002,202310119(all to RX).; Amyotrophic lateral sclerosis is a neurodegenerative disease,and the molecular mechanism underlying its pathology remains poorly understood.However,inflammation is known to play an important role in the development of...; 关键词：amyotrophic lateral sclerosis DRIVER NEUROINFLAMMATION OSMR C9ORF72 neurodegenerative disease PATHOGENESIS oxidative stress protein misfolding mitochondrial dysfunction

Biochanin A attenuates spinal cord injury in rats during early stages by inhibiting oxidative stress and inflammasome activation被引量：3: 《Neural Regeneration Research》2024年第9期2050-2056,共7页Xigong Li Jing Fu Ming Guan Haifei Shi Wenming Pan Xianfeng Lou; supported by the National Natural Science Foundation of China,Nos.LY20H090018(to XL)and LY20H060008(to HS).; Previous studies have shown that Biochanin A,a flavonoid compound with estrogenic effects,can serve as a neuroprotective agent in the context of cerebral ischemia/reperfusion injury;howeve r,its effect on spinal cord ...; 关键词：apoptosis AUTOPHAGY Biochanin A heme oxygenase 1 INFLAMMATION Nrf2 protein nuclear factor kappa-B oxidative stress spinal cord injury Toll-like receptor 4

Activation of the wnt/β-catenin/CYP1B1 pathway alleviates oxidative stress and protects the blood-brain barrier under cerebral ischemia/reperfusion conditions被引量：11: 《Neural Regeneration Research》2024年第7期1541-1547,共7页Xingyong Chen Nannan Yao Yanguang Mao Dongyun Xiao Yiyi Huang Xu Zhang Yinzhou Wang; supported by the National Natural Science Foundation of China,No.81771250(to XC);the Natural Science Foundation of Fujian Province,Nos.2020J011059(to XC),2020R1011004(to YW),2021J01374(to XZ);Medical Innovation Project of Fujian Province,No.2021 CXB002(to XC);Fujian Research and Training Grants for Young and Middle-aged Leaders in Healthcare(to XC)。; Accumulating evidence suggests that oxidative stress and the Wnt/β-catenin pathway participate in stroke-induced disruption of the blood-brain barrier.However,the potential links between them following ischemic strok...; 关键词：blood-brain barrier CYP1B1 oxidative stress oxygen glucose deprivation/reoxygenation tight junction vascular endothelial cells Wnt/β-catenin pathway β-catenin

Blood-brain barrier pathology in cerebral small vessel disease被引量：6: 《Neural Regeneration Research》2024年第6期1233-1240,共8页Ruxue Jia Gemma Solé-Guardia Amanda J.Kiliaan; supported by China Scholarship Council(202208210093,to RJ)。; Cerebral small vessel disease is a neurological disease that affects the brain microvasculature and which is commonly observed among the elderly.Although at first it was considered innocuous,small vessel disease is no...; 关键词：blood-brain barrier dysfunction cerebral blood flow cerebral hypoperfusion endothelial dysfunction HYPERTENSION inflammation magnetic resonance imaging neurovascular unit oxidative stress small vessel disease tight junctions TRANSCYTOSIS

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